RIGHT HEART FAILURE

This study tests whether giving two inhaled drugs (milrinone and epoprostenol) before heart-lung bypass can prevent difficult separation from the machine. About 141 adults having heart surgery will be randomly assigned to receive the drug combo or a placebo. The goal is to see if…

This study is testing whether valsartan, a drug already used for high blood pressure, can help people with pulmonary arterial hypertension (PAH). Researchers will give 60 adults either valsartan or a placebo for 24 weeks to see if it improves how far they can walk in six minutes …

This phase 2 trial is testing whether two existing drugs, empagliflozin (used for diabetes) and ranolazine (used for chest pain), can improve right heart function in 30 people with pulmonary hypertension and right heart failure. Participants will receive one of the drugs plus sta…

This study observes 500 adults in intensive care with acute respiratory distress syndrome (ARDS) who are on mechanical ventilation. Researchers will use heart ultrasounds and medication data to track how often right heart failure occurs and how it changes over time. The goal is t…

This study looks at data from the HeartMate 3 heart pump to see if it can help predict problems like bleeding, infection, or frailty in people with advanced heart failure. Researchers will track 150 adults getting the pump and compare pump alarms and readings to their health over…

This study is testing a new way to measure liver function in adults who have had the Fontan procedure, a surgery for certain heart defects. Researchers will use a dual cholate clearance test (a special blood test) and a heart MRI to see how well the liver is working. They will co…