RIGHT HEART FAILURE

This study tests whether adding empagliflozin or ranolazine to standard treatment can improve right heart function in 30 adults with pulmonary hypertension and right heart failure. Participants are randomly assigned to one of the two drugs plus usual care, or usual care alone. Th…

This study tests whether valsartan, a drug already used for high blood pressure, can help people with pulmonary arterial hypertension (PAH). About 60 adults with PAH will receive either valsartan or a placebo for 24 weeks. Researchers will measure how far they can walk in six min…

This study aims to see if a special liver function test (dual cholate clearance) can accurately measure liver health in people with Fontan circulation, a condition where blood flow to the liver is often impaired. Researchers will compare results from Fontan patients, people with …

This study will collect information from HeartMate 3 heart pumps in 150 adults to see if pump data can predict problems like bleeding, infection, or frailty. Researchers want to understand how pump readings relate to patients' quality of life and health outcomes. The goal is to h…

This study looks at how the heart and lungs affect each other in adults with acute respiratory distress syndrome (ARDS), a severe lung injury often caused by infections. Researchers will track 500 intensive care patients on ventilators using heart ultrasounds and medication recor…