Pacemaker showdown: which new technology is safer for your heart?

NCT ID NCT07534917

Not yet recruiting Knowledge-focused Sponsor: Guy's and St Thomas' NHS Foundation Trust Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study will compare two newer pacemaker technologies—left bundle branch area pacing and leadless pacing—to see how they affect heart function and the tricuspid valve. Twenty adults with certain heart block conditions will receive both types temporarily during their routine pacemaker procedure. The goal is to understand which approach may be better for preventing heart and valve damage.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: temporary left bundle branch area pacing and temporary leadless right ventricular pacing
What this could lead to: If successful, this study could help doctors choose the best pacemaker type for patients, potentially reducing heart and valve damage.
What could go wrong: This is a very small, early study (20 people) looking only at immediate effects during the procedure, not long-term outcomes. Results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

atrioventricular block Mobitz type II atrioventricular block third-degree atrioventricular block tricuspid valve insufficiency Ventricular Dysfunction, Right

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PACEMAKER-INDUCED CARDIOMYOPATHY RIGHT VENTRICULAR DYSFUNCTION TRICUSPID REGURGITATION

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