Heart drugs may boost recovery after valve surgery

NCT ID NCT07539259

First seen Apr 29, 2026

Summary

This study tests whether two heart failure medications, dapagliflozin and spironolactone, can help the heart recover better after aortic valve replacement. About 445 adults with severe aortic stenosis will take one or both drugs daily for 12 months. The goal is to see if these medicines reduce heart muscle thickness and scarring, improving long-term heart function.

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Conditions

The condition(s) this trial relates to.

aortic valve stenosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.