New sedative may cut delirium risk in elderly heart surgery patients
NCT ID NCT07265128
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study compares two sedatives, remimazolam and midazolam, to see which one causes less confusion (delirium) after heart valve surgery in people aged 65 and older. Delirium affects up to 70% of older heart surgery patients and can lead to longer hospital stays and memory problems. The trial will randomly assign 300 participants to receive one of the two drugs during surgery and monitor them for four days afterward.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Remimazolam (a fast-acting sedative) and midazolam (a standard sedative)
- What this could lead to
- If remimazolam works better, it could offer a safer sedative option for older heart surgery patients, reducing confusion and recovery time.
- What could go wrong
- This is a single-center trial with 300 patients, so results may not apply to all hospitals. The difference between the two drugs might be small or none.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Department of Anaesthesiology and Pain Medicine, Yonsei University College of Medicine
Seoul, 120-752, South Korea
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