Could a simple antibiotic combo save lives after heart valve surgery?
NCT ID NCT07442357
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study will test whether giving an extra antibiotic during a heart valve replacement procedure (TAVI) can lower the chance of bloodstream infection or death within 6 months. About 2,000 patients in Denmark will take part. Half will get the standard antibiotic, and half will get the standard plus an extra one targeting a specific bacteria.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Beta-lactam antibiotic (e.g., ampicillin) plus cephalosporin
What this could lead to
If it works, this could point toward a better way to prevent serious infections after heart valve replacement, potentially saving lives.
What could go wrong
This trial hasn't started yet, and it's testing a small change in routine care. The benefit may be small or not exist, and adding antibiotics carries risks like allergic reactions or antibiotic resistance.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Copenhagen University Hospital, Rigshospitalet
Copenhagen, Denmark