Heart surgery boost: could adenosine be the key to better recovery?

NCT ID NCT07426237

Not yet recruiting Disease control Sponsor: Hospital Nossa Senhora da Conceicao Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether adding adenosine to the standard heart-protecting solution used during bypass surgery helps the heart recover better. Sixty adults having elective valve or bypass surgery will receive either adenosine or a placebo. Researchers will measure heart function, heart damage markers, and the need for supportive drugs after surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Adenosine
What this could lead to: If it works, this could lead to a simple, low-cost way to better protect the heart during open-heart surgery, potentially reducing complications and speeding recovery.
What could go wrong: This is a small, early-phase trial (60 participants) testing a single dose. The benefit may be small or not seen at all, and there is a risk of side effects like arrhythmias.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

coronary artery disorder heart valve disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MYOCARDIAL PROTECTION

Contacts and locations

Locations

Hospital Nossa Senhora da Conceição

Porto Alegre, Rio Grande do Sul, 91350-200, Brazil

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