Heart drug warfarin under scrutiny for male fertility risks

NCT ID NCT07330869

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This pilot study will follow 90 men aged 18-50 who need heart surgery, some of whom will take the blood thinner warfarin afterward. Researchers will track changes in sperm count, movement, shape, DNA health, and hormone levels over 12 months. The goal is to see if warfarin harms male fertility, which could help doctors better counsel patients about family planning.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

warfarin

What this could lead to

If this study finds a link, it could lead to better counseling and fertility preservation for young men needing warfarin after heart surgery.

What could go wrong

This is a small pilot study, not a treatment trial. It only observes possible effects and cannot prove cause. Results may not apply to all men.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

heart valve disorder Inflammation male infertility

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Città di Lecce Hospital - Department of Cardiac Surgery

    Lecce, LE, 73100, Italy

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    Contact Phone: •••-•••-•••• Email: •••••@•••••

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    Contact Phone: •••-•••-•••• Email: •••••@•••••

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