Anxiety
MONDO:0011918Also known as: anxiety, anxiety-related personality traits, harm avoidance
1001 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsBroader categories
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Could a glass of Alcohol-Free wine boost your brain?
Disease control TerminatedThis study tests whether polyphenols from muscadine wine, served as a non-alcoholic beverage, can improve cognitive performance, memory, mood, and anxiety in healthy adults over 50. Participants will drink either the polyphenol-rich beverage or a placebo and complete a series of …
Phase: NA • Sponsor: University of Florida • Aim: Disease control
Last updated Aug 12, 2026 00:00 UTC
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A helping hand after burns: could support workers save lives?
Disease control OngoingThis trial tests whether a culturally adapted program of case manager support can improve survival, reduce hospital readmissions, and boost quality of life for adults recovering from accidental burn injuries in Pakistan. Participants receive up to eight sessions with a case manag…
Phase: NA • Sponsor: Pakistan Institute of Living and Learning • Aim: Disease control
Last updated Aug 05, 2026 00:00 UTC
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Online course aims to boost mental health for teens leaving foster care
Disease control OngoingThis study tests an online program called SYNC designed to help youth aged 16-20 in foster care manage stress, build coping skills, and feel more comfortable seeking mental health help. Participants take part in an 8-module online curriculum with support from service providers an…
Phase: NA • Sponsor: Portland State University • Aim: Disease control
Last updated Jul 12, 2026 00:00 UTC
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Can a Nurse-Led program transform Women's health in hong kong?
Disease control OngoingThis trial tests a nurse-led health program for women aged 45 to 64 in Hong Kong. The program uses a 5-step approach (ask, advice, assess, assist, arrange) to help women manage conditions like high blood pressure, anxiety, and menopause symptoms. Researchers will compare the prog…
Phase: NA • Sponsor: The University of Hong Kong • Aim: Disease control
Last updated Jun 27, 2026 12:25 UTC
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Phone support aims to improve mental health care in primary clinics
Disease control OngoingThis study tests a phone-based care management program for adults with depression, anxiety, or risky drinking. Participants get regular check-ins and support from a mental health technician, while their primary care doctor receives treatment recommendations. The goal is to see if…
Phase: NA • Sponsor: Centre for Addiction and Mental Health • Aim: Disease control
Last updated Jun 27, 2026 12:07 UTC
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Cool roofs may cool minds: trial targets Heat-Driven anxiety
Disease control OngoingThis study tests whether painting roofs with a special reflective coating can lower indoor temperatures and improve mental health. About 800 people in Ahmedabad, India, who live in homes with poor insulation will be randomly assigned to get a cool roof or not. Researchers will me…
Phase: NA • Sponsor: Aditi Bunker • Aim: Disease control
Last updated Jun 27, 2026 09:08 UTC
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Exercise as medicine: new trial tests group workouts for mental health
Disease control OngoingThis study compares a structured group exercise program called Braining with standard advice to exercise on your own. Over 12 weeks, 208 psychiatric patients will attend up to three clinician-led exercise sessions per week. Researchers will measure physical activity, depressive s…
Phase: NA • Sponsor: Region Stockholm • Aim: Disease control
Last updated Jun 27, 2026 08:06 UTC
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Happy older latinos are active: a walk a day may keep the blues away
Prevention OngoingThis study tests whether a health promotion program can prevent anxiety and depression in older Latino adults who are at risk. 240 participants will either join a program with group walks and social sessions led by a community health worker, or attend a healthy lifestyles educati…
Phase: NA • Sponsor: University of Miami • Aim: Prevention
Last updated Jun 27, 2026 12:33 UTC
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Firefighter trainees get mental health training to prevent PTSD and depression
Prevention ENROLLING_BY_INVITATIONThis study tests whether a workshop led by fellow firefighters can help prevent PTSD, depression, anxiety, and alcohol problems in new firefighter recruits. About 480 trainees will take part in either an emotion regulation workshop or a standard education session during their aca…
Phase: NA • Sponsor: Baylor Research Institute • Aim: Prevention
Last updated Jun 27, 2026 09:05 UTC
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New app aims to prevent stress in rural first responders
Prevention ENROLLING_BY_INVITATIONThis study tests a mobile app called FirstFocus that uses attention training to help first responders in rural areas prevent stress and mental health issues like anxiety and depression. About 80 active first responders aged 18+ with an iPhone will use the app before and after shi…
Phase: NA • Sponsor: Palo Alto University • Aim: Prevention
Last updated Jun 27, 2026 08:02 UTC
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Ear seeds may boost IVF success by calming anxiety
Symptom relief ENROLLING_BY_INVITATIONThis study tests whether a simple ear acupressure technique, called auricular point sticking therapy, can reduce anxiety and improve sleep in women undergoing IVF. 178 women aged 20-45 with anxiety or insomnia will either receive standard IVF care or standard care plus ear acupre…
Phase: NA • Sponsor: Hangzhou TCM Hospital Affiliated to Zhejiang Chinese Medical University • Aim: Symptom relief
Last updated Aug 16, 2026 00:00 UTC
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Nature as therapy? a new trial tests outdoor outings for anxious kids
Symptom relief TerminatedThis trial tests whether spending time in nature can reduce anxiety in children aged 9-12 who have experienced adverse childhood events. Participants are assigned to either group nature outings, family outings, or a waitlist. The goal is to see if these nature-based activities im…
Phase: NA • Sponsor: University of California, San Francisco • Aim: Symptom relief
Last updated Aug 16, 2026 00:00 UTC
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Rubber band trick may take the sting out of IV needles
Symptom relief ENROLLING_BY_INVITATIONThis study tests whether using a hand extension rubber during IV insertion can reduce pain, anxiety, and improve satisfaction. Researchers will enroll 114 adults who need an IV and randomly assign them to use the rubber or not. The goal is to see if this simple, low-cost distract…
Phase: NA • Sponsor: Necmettin Erbakan University • Aim: Symptom relief
Last updated Aug 15, 2026 00:00 UTC
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Faith-Based therapy aims to heal trauma in young women
Symptom relief OngoingThis trial tests a counseling program called Mpata Yathu ('Our Space') for adolescent girls and young women in Zambia who have experienced gender-based violence and may be living with or at risk for HIV. The program uses problem-solving therapy delivered by trained lay counselors…
Phase: NA • Sponsor: University of California, San Francisco • Aim: Symptom relief
Last updated Aug 14, 2026 00:00 UTC
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School Stress-Busting program for LGBTQ teens shows promise, but study cut short
Symptom relief OngoingThis study tested a school-based program called Proud & Empowered, designed to help LGBTQ students cope with minority stress and improve mental health. About 228 high school students took part. The program was led by school counselors and social workers. The study was terminated …
Phase: NA • Sponsor: Washington University School of Medicine • Aim: Symptom relief
Last updated Aug 12, 2026 00:00 UTC
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Could a simple playlist be the new painkiller? Music's power over surgery anxiety put to the test
Symptom relief OngoingThis trial tests whether listening to music for 30 minutes before and after surgery can reduce pain, anxiety, and the need for painkillers in women undergoing gynecologic surgery. Participants will choose from several music genres and report their pain, anxiety, and satisfaction …
Phase: NA • Sponsor: KK Women's and Children's Hospital • Aim: Symptom relief
Last updated Aug 09, 2026 00:00 UTC
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A simple breath: could guided breathing calm heart failure symptoms?
Symptom relief OngoingThis trial tests whether nurse-guided breathing exercises can reduce shortness of breath and anxiety in people with advanced heart failure who come to the emergency department. Participants are randomly assigned to receive either standard care plus guided diaphragmatic and pursed…
Phase: NA • Sponsor: Istanbul University - Cerrahpasa • Aim: Symptom relief
Last updated Aug 09, 2026 00:00 UTC
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Could a VR headset replace pills for surgery anxiety?
Symptom relief OngoingThis trial tests whether using virtual reality (VR) relaxation before and after gynecologic surgery can reduce anxiety and pain. About 220 women undergoing day or inpatient gynecologic procedures will either use a VR headset with calming scenes or receive standard care. Researche…
Phase: NA • Sponsor: KK Women's and Children's Hospital • Aim: Symptom relief
Last updated Aug 09, 2026 00:00 UTC
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Can a buzzing bee or a fingertip tap erase the sting of baby shots?
Symptom relief OngoingThis study tests whether two simple, drug-free techniques can ease the pain, fear, and crying that 9-month-old babies often experience during routine vaccinations. One method uses a small bee-shaped device called Buzzy, which vibrates and cools the skin near the injection site. T…
Phase: NA • Sponsor: Ege University • Aim: Symptom relief
Last updated Aug 08, 2026 00:03 UTC
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Can a phone app tame workplace burnout for officers working with troubled youth?
Symptom relief OngoingThis study tests whether a smartphone app called AIM+ can help juvenile justice officers and other professionals who work with youth in the legal system manage chronic stress, anxiety, and burnout. Over 30 days, participants use the app for short guided meditations and videos. Th…
Phase: NA • Sponsor: University of Illinois at Chicago • Aim: Symptom relief
Last updated Aug 07, 2026 00:00 UTC
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Can a meditation app fix sleep for blood cancer patients?
Symptom relief OngoingThis study looks at whether using the Calm meditation app for 10 minutes a day can help blood cancer patients who have trouble sleeping. Researchers will track sleep, mood, and inflammation in 276 participants over 20 weeks. The goal is to find a simple, drug-free way to improve …
Phase: NA • Sponsor: The University of Texas Health Science Center at San Antonio • Aim: Symptom relief
Last updated Aug 07, 2026 00:00 UTC
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Could a tiny zap to the head beat anxiety? military tests new device
Symptom relief OngoingThis study tests whether a device called CES (cranial electrotherapy stimulation) can reduce anxiety symptoms in 200 active-duty military members and their families. Participants receive either real CES or a sham (placebo) device to see if the gentle electrical pulses truly help.…
Phase: NA • Sponsor: David Moss • Aim: Symptom relief
Last updated Aug 06, 2026 00:00 UTC
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Magic mushroom therapy aims to ease cancer Patients' fear and sadness
Symptom relief OngoingThis study tests whether a group retreat using psilocybin (the active ingredient in magic mushrooms) can safely reduce anxiety and depression in people with incurable cancer. Participants will receive a pharmaceutical-grade psilocybin along with guided discussions to help them ga…
Phase: PHASE2 • Sponsor: University of Washington • Aim: Symptom relief
Last updated Aug 02, 2026 00:00 UTC
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Smartphone therapy could ease long COVID's mental toll
Symptom relief TerminatedThis study tests a coach-guided digital therapeutic called Toivoa-004, designed to help adults with Long COVID manage symptoms of anxiety and depression. The program delivers cognitive behavioral therapy through a smartphone app and is built to be accessible for people with disab…
Phase: NA • Sponsor: Toivoa Inc • Aim: Symptom relief
Last updated Jul 31, 2026 00:00 UTC
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New study tests At-Home programs to ease pain and anxiety after cancer surgery
Symptom relief OngoingThis study compares two different remote support programs to see which one helps women feel better after surgery for suspected gynecological cancer. About 160 women will take part, and researchers will measure pain, mood, and sleep quality. The goal is to find simple, at-home way…
Phase: PHASE3 • Sponsor: Wake Forest University Health Sciences • Aim: Symptom relief
Last updated Jul 26, 2026 00:00 UTC
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Holograms may replace needles for burn dressing pain
Symptom relief OngoingThis study tests whether showing 3D hologram videos during burn dressing changes can reduce pain, anxiety, and fear in patients. 70 adults will be randomly assigned to either watch a hologram or receive standard care. The hologram projects interactive images into the air without …
Phase: NA • Sponsor: Gamze BULUT • Aim: Symptom relief
Last updated Jul 25, 2026 00:00 UTC
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Simple vibration or breathing may take the sting out of chest tube removal
Symptom relief OngoingThis study tests two simple, drug-free methods—vibration and breathing exercises—to see if they can reduce pain and anxiety when a chest tube is removed after surgery. About 70 adults will be randomly assigned to vibration, breathing exercises, or standard care. If effective, the…
Phase: NA • Sponsor: Gamze BULUT • Aim: Symptom relief
Last updated Jul 25, 2026 00:00 UTC
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Magnetic pulses to the brain may calm anxiety in Parkinson's — a trial puts it to the test
Symptom relief ENROLLING_BY_INVITATIONThis trial tests whether a non-invasive brain stimulation technique called transcranial magnetic stimulation (TMS) can reduce anxiety in people with Parkinson's disease. Anxiety affects up to 40% of people with Parkinson's, and standard medications often fall short or cause side …
Phase: NA • Sponsor: HealthPartners Institute • Aim: Symptom relief
Last updated Jul 24, 2026 00:00 UTC
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Can sound waves calm both seizures and anxiety?
Symptom relief OngoingThis early-stage trial is testing whether a non-invasive procedure called focused ultrasound can safely reduce both seizures and anxiety in people with treatment-resistant epilepsy. The ultrasound targets a small region in the brain thought to be involved in both conditions. Rese…
Phase: PHASE1 • Sponsor: Ohio State University • Aim: Symptom relief
Last updated Jul 24, 2026 00:00 UTC
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Music mindfulness trial aims to soothe anxious kids
Symptom relief ENROLLING_BY_INVITATIONThis study tests whether a community-based music mindfulness program can reduce anxiety and depression in children aged 8-12 with ADHD or anxiety. Participants attend bi-weekly sessions for 8 weeks, wear fitness trackers, and complete surveys. The goal is to see if this approach …
Phase: NA • Sponsor: State University of New York at Buffalo • Aim: Symptom relief
Last updated Jul 16, 2026 00:00 UTC
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Could CBD be the next frontier for anxiety relief?
Symptom relief OngoingThis study investigates whether a hemp-derived cannabidiol (CBD) extract can safely reduce anxiety and improve sleep in adults with moderate to severe anxiety. Over four weeks, participants take 50 to 150 mg of CBD daily, with doses adjusted based on tolerance. The trial tracks s…
Phase: PHASE2 • Sponsor: University of Florida • Aim: Symptom relief
Last updated Jul 11, 2026 00:00 UTC
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Sniffing essential oils during surgery may ease anxiety and mask burnt flesh smell
Symptom relief OngoingThis study tests whether smelling essential oils during skin surgery can reduce the unpleasant smell of burnt flesh from electrocautery and lower patient anxiety. About 111 adults having same-day skin procedures will be randomly assigned to receive either a real essential oil inh…
Phase: NA • Sponsor: Northwestern University • Aim: Symptom relief
Last updated Jul 03, 2026 00:00 UTC
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Online therapy could ease anxiety in autistic teens
Symptom relief OngoingThis study tests an internet-based cognitive behavioral therapy (CBT) program designed to help autistic adolescents aged 11-17 manage anxiety. The program, called LUNA-Adolescent, is parent-led and delivered online, making it easier for families who cannot access in-person therap…
Phase: NA • Sponsor: Baylor College of Medicine • Aim: Symptom relief
Last updated Jul 02, 2026 00:00 UTC
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Can virtual reality or a simple schedule change ease kids' fear during pin removal?
Symptom relief ENROLLING_BY_INVITATIONThis study looks at two ways to lower anxiety in children aged 3 to 10 who need surgical pins removed from an elbow fracture. One approach removes the pins right after the cast comes off, before an X-ray, instead of after. The other uses a virtual reality headset during the pin r…
Phase: NA • Sponsor: Boston Children's Hospital • Aim: Symptom relief
Last updated Jul 02, 2026 00:00 UTC
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Can a buddy system boost mental health during hormone therapy?
Symptom relief OngoingThis study looks at whether a peer support program is acceptable and helpful for people with mild depression or anxiety who are starting or receiving hormone care. One hundred participants are randomly assigned to either the peer support group or usual care. The program includes …
Phase: NA • Sponsor: University of Michigan • Aim: Symptom relief
Last updated Jun 28, 2026 00:00 UTC
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One therapy to tackle both anxiety and drinking in veterans?
Symptom relief OngoingThis study tests a single cognitive behavioral therapy (CBT) program designed to help veterans who struggle with both anxiety (including PTSD) and hazardous drinking. The goal is to see if treating both issues together improves their daily functioning and reduces symptoms better …
Phase: NA • Sponsor: VA Office of Research and Development • Aim: Symptom relief
Last updated Jun 27, 2026 14:00 UTC
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Ancient chinese music tunes tested as depression treatment
Symptom relief ENROLLING_BY_INVITATIONThis study tests whether a unique music therapy, based on Traditional Chinese Medicine's five-element theory, can help men with depression and anxiety when added to their usual medication. One hundred male inpatients will receive either standard drugs alone, drugs plus regular mu…
Phase: NA • Sponsor: University of Malaya • Aim: Symptom relief
Last updated Jun 27, 2026 14:00 UTC
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Cancer survivors find hope in Peer-Led Self-Management program
Symptom relief OngoingThis study tests a 7-session, peer-led self-management program for 234 cancer survivors who recently finished treatment with curative intent. The program aims to reduce anxiety and depression by teaching symptom management skills in a group setting. Participants are from central …
Phase: NA • Sponsor: University of Aarhus • Aim: Symptom relief
Last updated Jun 27, 2026 13:08 UTC
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New CalmER therapy aims to lower anxiety in hospital staff
Symptom relief OngoingThis study tests whether a new therapy called Emotional Resolution (EmRes) can help reduce anxiety in healthcare workers. About 150 hospital workers with mild to moderate anxiety will either receive EmRes or a mindfulness-based gratitude exercise. The goal is to see if EmRes lead…
Phase: NA • Sponsor: University of California, Los Angeles • Aim: Symptom relief
Last updated Jun 27, 2026 13:06 UTC
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One-Time digital tool may help kids stuck on therapy waitlists
Symptom relief OngoingThis study tests a single online session that teaches a simple coping skill to youth ages 9-17 who are on a waitlist for therapy. The goal is to see if this quick digital tool can help ease symptoms of anxiety, depression, and stress while they wait. About 226 youth and their par…
Phase: NA • Sponsor: Harvard University • Aim: Symptom relief
Last updated Jun 27, 2026 13:05 UTC
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Can rewriting your life story improve mental health? small trial tests new therapy
Symptom relief OngoingThis study tests a therapy called RETELL that helps people with severe mental illness explore and reshape their life stories. The goal is to improve personal recovery, quality of life, and identity. Twenty adults with conditions like schizophrenia, bipolar disorder, or PTSD will …
Phase: NA • Sponsor: University of Aarhus • Aim: Symptom relief
Last updated Jun 27, 2026 13:04 UTC
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New program aims to help veterans with COPD breathe easier and feel better
Symptom relief OngoingThis study tests an 8-week program called Step-CBT that combines physical activity goals with cognitive behavioral therapy for veterans with COPD who also have depression or anxiety. The program is delivered via video calls to make it accessible. Researchers want to see if it is …
Phase: NA • Sponsor: VA Office of Research and Development • Aim: Symptom relief
Last updated Jun 27, 2026 13:00 UTC
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Can a phone app and a coach help Spanish-Speaking patients beat depression?
Symptom relief ENROLLING_BY_INVITATIONThis study tests a digital cognitive behavioral therapy program (SilverCloud) for Spanish-speaking adults with depression or anxiety. 426 participants will either use the program on their own or get extra support from a peer coach via phone or messaging. The goal is to see if add…
Phase: NA • Sponsor: University of California, Irvine • Aim: Symptom relief
Last updated Jun 27, 2026 12:35 UTC
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Mindfulness may ease stress and anxiety in COPD patients, small study suggests
Symptom relief OngoingThis pilot study tests whether an 8-week mindfulness program (MBSR) can reduce anxiety, depression, and stress in people with COPD who are already in pulmonary rehab. About 44 participants will be followed for 12 months. The goal is to see if this mind-body approach improves emot…
Phase: NA • Sponsor: Université Libre de Bruxelles • Aim: Symptom relief
Last updated Jun 27, 2026 12:35 UTC
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Pregnancy stress? a Step-Count program might help
Symptom relief ENROLLING_BY_INVITATIONThis study tests whether a physical activity program can help pregnant people with symptoms of depression or anxiety feel better. 88 participants will be given a step goal and wear an activity tracker. The program includes weekly reminders and motivational coaching every two week…
Phase: NA • Sponsor: Stanford University • Aim: Symptom relief
Last updated Jun 27, 2026 12:34 UTC
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Can online therapy ease anxiety in kids with asthma? new study explores
Symptom relief OngoingThis study tests whether an online cognitive behavior therapy (CBT) program can help children aged 8 to 17 with asthma who also feel anxious or worried about their condition. The therapy is designed to improve quality of life, reduce anxiety, and help manage asthma better. The st…
Phase: NA • Sponsor: Karolinska Institutet • Aim: Symptom relief
Last updated Jun 27, 2026 12:32 UTC
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Can a mindfulness app soothe young minds scarred by early trauma?
Symptom relief OngoingThis study tests a mindfulness program (called GEM) delivered through an app and weekly group video calls. It aims to see if young adults (ages 18-24) who have faced early life hardships find the program helpful and easy to use. The study also checks if the program reduces sympto…
Phase: NA • Sponsor: Brown University • Aim: Symptom relief
Last updated Jun 27, 2026 12:32 UTC
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Internet CBT shows promise for stressed students
Symptom relief OngoingThis study tests an online cognitive behavioral therapy (CBT) program for university students with mild depression or anxiety. Two hundred students who previously took a mental health survey will receive a tailored internet treatment. The goal is to see if this e-health approach …
Phase: NA • Sponsor: Uppsala University • Aim: Symptom relief
Last updated Jun 27, 2026 12:30 UTC
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Sound therapy: a 9-Minute fix for anxiety and stress?
Symptom relief ENROLLING_BY_INVITATIONThis study tests whether listening to specific sound frequencies for just 9 minutes a week can improve mental health. 110 adults with mild anxiety, stress, or depression will either sit in a special sound chamber or use headphones. The goal is to see if this simple, drug-free app…
Phase: NA • Sponsor: Federal University of Minas Gerais • Aim: Symptom relief
Last updated Jun 27, 2026 12:30 UTC
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Can a few minutes of meditation each week ease cancer Patients' distress?
Symptom relief OngoingThis study looks at whether cancer patients can use a self-guided meditation program at home to reduce anxiety and depression. About 35 patients will try techniques like deep breathing or gentle movement for two weeks. The goal is to see if this simple, low-cost approach is pract…
Phase: NA • Sponsor: M.D. Anderson Cancer Center • Aim: Symptom relief
Last updated Jun 27, 2026 12:29 UTC
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Can a website beat the blues? new study tests online CBT for stressed students
Symptom relief OngoingThis study tests whether an internet-based self-help program called VIVIM can help university students with anxiety and depression. About 108 students will be randomly assigned to use VIVIM or receive usual support from their university counseling service. They will fill out ques…
Phase: NA • Sponsor: University Rovira i Virgili • Aim: Symptom relief
Last updated Jun 27, 2026 12:29 UTC
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New program aims to heal war trauma passed down in refugee families
Symptom relief OngoingThis study tests a program that combines family group sessions with a virtual peer mentoring program for US-born teens (ages 14-17) whose parents resettled as refugees. The goal is to reduce symptoms of PTSD, depression, anxiety, and behavior problems caused by intergenerational …
Phase: NA • Sponsor: Washington University School of Medicine • Aim: Symptom relief
Last updated Jun 27, 2026 12:28 UTC
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Music festival anxiety study pulled before it began
Symptom relief TerminatedThis study planned to test whether a lidocaine nerve block (SPG block) could reduce anxiety in adults at electronic dance music festivals, compared to a saline placebo. The trial was withdrawn before enrolling any participants, so no data were collected. The approach was experime…
Phase: PHASE2 • Sponsor: University of Calgary • Aim: Symptom relief
Last updated Jun 27, 2026 12:28 UTC
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Could a 30-Minute online session help while you wait for therapy?
Symptom relief ENROLLING_BY_INVITATIONThis study tests a brief digital mental health program for people on waiting lists for psychological treatment. About 80 participants will be randomly assigned to one of four groups: a short program (30-40 minutes), a longer version, or control conditions. The main goal is to see…
Phase: NA • Sponsor: University of Oslo • Aim: Symptom relief
Last updated Jun 27, 2026 12:28 UTC
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New group therapy aims to curb suicide risk in active duty troops
Symptom relief OngoingThis study tests a 12-session group therapy program (G-BCBT) for active duty military personnel who have recent suicidal thoughts or a recent suicide attempt. The therapy teaches emotion regulation, cognitive flexibility, and relapse prevention skills. Researchers will measure ch…
Phase: NA • Sponsor: University of North Carolina, Charlotte • Aim: Symptom relief
Last updated Jun 27, 2026 12:24 UTC
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Zapping the brain while meditating in VR: a new anxiety fix?
Symptom relief ENROLLING_BY_INVITATIONThis study tests whether combining a mild electrical brain stimulation (tDCS) with virtual reality meditation can help ease anxiety. 52 adults with generalized anxiety disorder or related conditions will receive 12 sessions over two weeks. Researchers will measure anxiety levels …
Phase: NA • Sponsor: The University of Hong Kong • Aim: Symptom relief
Last updated Jun 27, 2026 12:24 UTC
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Can a phone app ease stress in older korean immigrants?
Symptom relief ENROLLING_BY_INVITATIONThis study looks at whether using a mindfulness app on a smartphone for 8 weeks can improve mental health in Korean immigrants aged 60 and older. Participants use the app for about 10-15 minutes daily and have weekly check-ins. The goal is to see if the app is easy to use and hel…
Phase: NA • Sponsor: University of South Florida • Aim: Symptom relief
Last updated Jun 27, 2026 12:23 UTC
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Study canceled: virtual parent vs. sedative for Kids' surgery anxiety
Symptom relief TerminatedThis study aimed to see if having a parent appear on a video call during anesthesia induction could reduce children's anxiety as effectively as the sedative midazolam. It was designed for children aged 4 to 8 undergoing outpatient surgery. However, the study was withdrawn before …
Phase: NA • Sponsor: Stanford University • Aim: Symptom relief
Last updated Jun 27, 2026 12:23 UTC
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New therapy shows promise for troubled youth
Symptom relief OngoingThis study tests if a therapy called FIRST, which uses five key principles to help youth manage negative emotions, works better than standard therapy. About 212 youth aged 7 to 15 with anxiety, depression, trauma, or behavior problems will take part. The goal is to see if FIRST i…
Phase: NA • Sponsor: Harvard University • Aim: Symptom relief
Last updated Jun 27, 2026 12:09 UTC
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Sound waves to soothe anxiety? new study tests brain zapping without surgery
Symptom relief OngoingThis study tests whether a gentle ultrasound beam aimed at the brain can reduce anxiety. 44 people with high or low anxiety will receive either real or fake ultrasound while their reactions to stressful tasks are measured. The goal is to see if this noninvasive technique can damp…
Phase: NA • Sponsor: Virginia Polytechnic Institute and State University • Aim: Symptom relief
Last updated Jun 27, 2026 12:08 UTC
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New outreach program targets mental health gaps in latino communities
Symptom relief OngoingThis study tests a community-based program called CRISOL Mente to help Latinos in the Philadelphia area with depression, anxiety, or PTSD. The program uses outreach workers to connect people to mental health care and support. Researchers will measure if symptoms improve after six…
Phase: NA • Sponsor: Drexel University • Aim: Symptom relief
Last updated Jun 27, 2026 12:07 UTC
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Can a brief online therapy ease anxiety and depression in kids? new study aims to find out.
Symptom relief ENROLLING_BY_INVITATIONThis study tests a brief behavioral therapy program delivered via telehealth (STEP-UP) for children and teens aged 8 to 16 with anxiety or depression. Participants are recruited from community health centers and randomly assigned to either STEP-UP or a referral to local mental he…
Phase: NA • Sponsor: San Diego State University • Aim: Symptom relief
Last updated Jun 27, 2026 12:07 UTC
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New study tackles mom's stress and food needs to boost baby bonding
Symptom relief OngoingThis study aims to help mothers of babies in intensive care cope with depression, anxiety, and stress while also addressing basic needs like food and housing. About 200 caregivers of infants up to 6 months old will receive emotional support and referrals to community resources. T…
Sponsor: Baylor College of Medicine • Aim: Symptom relief
Last updated Jun 27, 2026 12:06 UTC
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Can a quick brain zap ease depression? new study seeks the sweet spot.
Symptom relief OngoingThis study tests an accelerated version of a brain stimulation treatment called TMS for people with depression and anxiety. Researchers want to find the best dose to reduce symptoms. About 70 adults will take part, and the study measures changes in mood using standard questionnai…
Phase: NA • Sponsor: Medical University of South Carolina • Aim: Symptom relief
Last updated Jun 27, 2026 12:03 UTC
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CBD spray calms Alzheimer's anxiety? early trial hints at relief
Symptom relief OngoingThis small, early-stage study tested a high-CBD, low-THC liquid spray for 8 weeks in 12 older adults with mild cognitive impairment or mild-to-moderate Alzheimer's who also had significant anxiety or agitation. The goal was to see if the treatment could reduce these behavioral sy…
Phase: EARLY_PHASE1 • Sponsor: Mclean Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 12:02 UTC
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Berry good news: compote may calm anxious minds
Symptom relief OngoingThis study tests whether a fruit compote made with maqui berry, prebiotics, and probiotics can reduce anxiety and inflammation in 30 university students aged 18-40. Participants eat the compote as part of their normal diet, and researchers measure changes in anxiety levels, stres…
Phase: NA • Sponsor: Samanta Thomas • Aim: Symptom relief
Last updated Jun 27, 2026 12:02 UTC
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Could a new therapy boost joy in Spanish-Speakers with depression?
Symptom relief OngoingThis pilot study tests a therapy called Positive Affect Treatment (PAT) for Spanish-speaking adults with depression, anxiety, and low positive affect (a lack of joy or interest). Twelve participants will attend 15 therapy sessions over about 4 months, focusing on pleasant activit…
Phase: NA • Sponsor: Southern Methodist University • Aim: Symptom relief
Last updated Jun 27, 2026 12:00 UTC
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Virtual reality videos calm heart surgery nerves, study finds
Symptom relief ENROLLING_BY_INVITATIONThis study looks at whether watching immersive videos before open-heart surgery can lower patients' anxiety and improve their recovery. About 200 adults scheduled for elective heart surgery will take part. Researchers will measure anxiety using questionnaires and vital signs befo…
Phase: NA • Sponsor: Baptist Health South Florida • Aim: Symptom relief
Last updated Jun 27, 2026 09:10 UTC
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Mindfulness for Moms-to-Be: could a special class ease pregnancy anxiety?
Symptom relief TerminatedThis study tests whether a mindfulness-based childbirth and parenting class can lower anxiety in pregnant women. Sixty women with elevated worry will be randomly assigned to either the mindfulness class or a standard childbirth education class. Researchers will track changes in a…
Phase: NA • Sponsor: University of Wisconsin, Madison • Aim: Symptom relief
Last updated Jun 27, 2026 09:08 UTC
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Breathe away the pressure: biofeedback trial targets student dentist anxiety
Symptom relief ENROLLING_BY_INVITATIONThis study tests whether a 5-week heart rate variability biofeedback program can lower stress and anxiety in 50 dentistry students moving from classroom to clinic. Participants in the training group practice slow breathing with real-time feedback, while a control group receives n…
Phase: NA • Sponsor: Egas Moniz - Cooperativa de Ensino Superior, CRL • Aim: Symptom relief
Last updated Jun 27, 2026 09:07 UTC
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Simple relaxation exercises may ease menopause symptoms
Symptom relief OngoingThis study tests whether progressive relaxation exercises and planned education can reduce menopause symptoms, stress, and anxiety in menopausal women. About 144 women will participate, with some receiving the relaxation and education program and others not. The goal is to see if…
Phase: NA • Sponsor: Cumhuriyet University • Aim: Symptom relief
Last updated Jun 27, 2026 09:06 UTC
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Can a brainwave device cure nurse burnout? small study hopes to find out
Symptom relief ENROLLING_BY_INVITATIONThis study tests a device called Cereset that plays tones to mirror your brainwaves, aiming to reduce stress, anxiety, insomnia, and depression. About 40 nurses from one hospital unit will use the device. The goal is to see if it improves their well-being and job performance.
Phase: NA • Sponsor: Wake Forest University Health Sciences • Aim: Symptom relief
Last updated Jun 27, 2026 09:06 UTC
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App plus therapist sessions may help WTC responders with PTSD
Symptom relief ENROLLING_BY_INVITATIONThis study tests whether a mobile app called PTSD Coach, with or without brief clinician support, can reduce PTSD, anxiety, depression, and sleep problems in World Trade Center responders living in Florida. About 120 English- or Spanish-speaking responders will be randomly assign…
Phase: NA • Sponsor: Florida International University • Aim: Symptom relief
Last updated Jun 27, 2026 09:05 UTC
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Art therapy: a new way to ease pain and anxiety for the dying?
Symptom relief ENROLLING_BY_INVITATIONThis study looks at whether one art therapy session can improve mood and reduce symptoms like pain and anxiety in adults receiving palliative care. Twenty patients in a Canadian hospital will fill out short questionnaires before and after a 30-60 minute art session. The goal is t…
Sponsor: Nova Scotia Health Authority • Aim: Symptom relief
Last updated Jun 27, 2026 09:05 UTC
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New app aims to tackle opioid crisis and mental health together
Symptom relief OngoingThis early-stage study is testing a smartphone app called NEAT-O that provides cognitive behavioral therapy (CBT) to adults with opioid use disorder who also have anxiety or depression. The goal is to see if the app is easy to use and acceptable to patients. If successful, it wil…
Phase: PHASE1 • Sponsor: University of Minnesota • Aim: Symptom relief
Last updated Jun 27, 2026 09:05 UTC
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Can a herbal drink calm cancer Survivors' anxiety? early trial halted
Symptom relief TerminatedThis pilot study tested whether kava, a herbal supplement, could safely reduce anxiety and stress in 43 cancer survivors who had completed treatment. Participants took either kava or a placebo for 14 days, then switched after a washout period. The trial is currently suspended, an…
Phase: EARLY_PHASE1 • Sponsor: Masonic Cancer Center, University of Minnesota • Aim: Symptom relief
Last updated Jun 27, 2026 09:05 UTC
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Music and mindfulness program aims to ease stress in african american communities
Symptom relief ENROLLING_BY_INVITATIONThis study tests whether a virtual, community-based program combining music and mindfulness can help reduce stress, anxiety, and depression in people of African descent. About 300 participants aged 16 and older will take part. The goal is to see if these culturally relevant activ…
Phase: NA • Sponsor: Yale University • Aim: Symptom relief
Last updated Jun 27, 2026 09:04 UTC
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Can an Anti-Inflammatory diet soothe anxiety and depression?
Symptom relief ENROLLING_BY_INVITATIONThis study looks at whether following an anti-inflammatory diet for 4 months can improve symptoms of anxiety and depression in 60 adults. Participants will either follow the special diet or their usual eating habits. The study also uses artificial intelligence to analyze speech a…
Phase: NA • Sponsor: Universidad de Zaragoza • Aim: Symptom relief
Last updated Jun 27, 2026 09:03 UTC
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Can a computer program help calm anxiety in dementia?
Symptom relief OngoingThis study tests a special therapy program delivered over the internet for people with mild cognitive impairment or dementia who also feel anxious. The program uses cognitive behavioral therapy (CBT) techniques to help manage worry and fear. Researchers will measure changes in an…
Phase: NA • Sponsor: The University of Queensland • Aim: Symptom relief
Last updated Jun 27, 2026 09:01 UTC
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Hug it out: study tests Pre-Surgery hugs for calmer patients
Symptom relief OngoingThis study looks at whether a simple hug from a family member before surgery can help lower anxiety and pain afterward. 160 adults having planned surgery will either hug for at least 20 seconds or follow standard care. Researchers will measure anxiety levels and pain scores to se…
Phase: NA • Sponsor: University of Health Sciences Balikesir Hospital Eduation and Research • Aim: Symptom relief
Last updated Jun 27, 2026 09:00 UTC
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No more tears at the dentist? new study tests fun videos and acupressure for Kids' tooth pulls
Symptom relief ENROLLING_BY_INVITATIONThis study looks at two simple ways to help children feel less anxious and in less pain when getting a tooth pulled. One method uses a fun video to distract them, and the other uses gentle pressure on a specific point on the hand. The study will include 69 healthy children aged 5…
Phase: NA • Sponsor: Mansoura University • Aim: Symptom relief
Last updated Jun 27, 2026 09:00 UTC
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Put down your phone to calm your nerves? mayo clinic tests the idea
Symptom relief OngoingThis Mayo Clinic study tests whether reducing overall smartphone use and avoiding social media apps like Facebook, Instagram, and TikTok can lower anxiety symptoms in adults. One hundred participants with mild anxiety will be asked to change their phone habits, and their anxiety …
Phase: NA • Sponsor: Mayo Clinic • Aim: Symptom relief
Last updated Jun 27, 2026 08:11 UTC
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Could a simple buzz replace needles' fear? stanford tests vibrating device on 1,100 patients
Symptom relief OngoingThis study tests a small vibrating device held near the skin during needle sticks (like IVs or blood draws) to see if it lowers pain and anxiety. About 1,100 children and adults will take part. Researchers will watch and ask about discomfort to see if the buzz helps people feel c…
Phase: NA • Sponsor: Stanford University • Aim: Symptom relief
Last updated Jun 27, 2026 08:08 UTC
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Could a fun group workout ease anxiety and depression in kids and teens?
Symptom relief ENROLLING_BY_INVITATIONThis study tests a 7-week group physical activity program called Confident, Active and Happy Youth (CAHY) for young people aged 8-17 with anxiety or depression. The program includes fun, non-competitive activities led by a therapist. Researchers want to see if it improves mood an…
Phase: NA • Sponsor: Haukeland University Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 08:08 UTC
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Virtual reality offers Drug-Free relief for surgery patients
Symptom relief OngoingThis study tests whether watching calming nature videos with virtual reality glasses can lower pain and anxiety in people recovering from colorectal surgery. Sixty adults will be split into two groups: one group uses the VR glasses before and after surgery, while the other receiv…
Phase: NA • Sponsor: Ankara Yildirim Beyazıt University • Aim: Symptom relief
Last updated Jun 27, 2026 08:05 UTC
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Sniff away the pain: aromatherapy tested for easier labor
Symptom relief ENROLLING_BY_INVITATIONThis study looks at whether breathing in aromatherapy scents can help pregnant women feel less pain, worry, and nausea during labor. About 128 women in labor will either receive the scents or standard care. Researchers will compare their symptoms before and after to see if the sc…
Phase: NA • Sponsor: Baptist Health South Florida • Aim: Symptom relief
Last updated Jun 27, 2026 08:04 UTC
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VR meditation study aims to ease pain and stress – but was pulled
Symptom relief TerminatedThis study planned to test whether virtual reality-based guided mindfulness meditation could help adults with anxiety, depression, stress, or pain feel better. Researchers wanted to see if using VR meditation was practical and if it improved mood and pain scores. However, the stu…
Phase: NA • Sponsor: University of California, Los Angeles • Aim: Symptom relief
Last updated Jun 27, 2026 08:04 UTC
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Can a gentle zap to the neck or ear calm body distress?
Symptom relief ENROLLING_BY_INVITATIONThis study compares two non-invasive devices that stimulate the vagus nerve—one placed on the neck, the other on the ear—to see which better reduces physical discomfort and health-related anxiety in people with somatic symptom disorder. Sixty participants will try both devices in…
Phase: NA • Sponsor: National Taiwan University Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 08:03 UTC
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Wearable patch promises stress relief without pills
Symptom relief OngoingThis study tests a topical patch called PEACE that uses gentle vibrations to help people feel less stressed or anxious. 150 adults aged 18 to 85 who have stress or anxiety will wear either the active patch or a sham (fake) patch for 14 days. Researchers will measure changes using…
Phase: NA • Sponsor: SuperPatch Limited LLC • Aim: Symptom relief
Last updated Jun 27, 2026 08:02 UTC
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Extra fibre, better mood? small study tests the link
Symptom relief OngoingThis study looks at whether adding 10 grams of fibre to your daily diet for two weeks can improve mental wellbeing, including anxiety, stress, sleep, and mood. Researchers will track changes in 40 healthy adults aged 18-40 using questionnaires. It's a small, early-stage trial to …
Phase: NA • Sponsor: University of Reading • Aim: Symptom relief
Last updated Jun 27, 2026 08:01 UTC
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Meditation before surgery may ease pain and anxiety for kidney stone patients
Symptom relief ENROLLING_BY_INVITATIONThis pilot study tests whether daily meditation can improve recovery for children and adults having surgery for kidney stones. Participants will be randomly assigned to either a meditation group or a control group. Those in the meditation group will practice a daily 20-minute gui…
Phase: NA • Sponsor: Children's Hospital of Philadelphia • Aim: Symptom relief
Last updated Jun 27, 2026 08:01 UTC
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Laughter yoga: a new way to beat exam stress?
Symptom relief OngoingThis study looks at whether laughter yoga can lower exam anxiety and improve spirituality in nursing students. About 36 students will do laughter yoga twice a week for 4 weeks, while another group does nothing. Researchers will compare anxiety and spirituality scores before and a…
Phase: NA • Sponsor: Kırıkkale University • Aim: Symptom relief
Last updated Jun 27, 2026 08:00 UTC
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Puppy power: study tests if therapy dogs can ease grad student stress
Symptom relief OngoingThis study looks at whether spending time with a therapy dog can reduce anxiety and stress in graduate students. Thirty first-year grad students will either interact with a therapy dog or receive general health education. Researchers will measure stress through saliva cortisol le…
Phase: NA • Sponsor: Wichita State University • Aim: Symptom relief
Last updated Jun 27, 2026 07:55 UTC
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Spiritual records sessions tested for mental health boost
Symptom relief OngoingThis study looks at whether two Akashic Records sessions can improve mental health in adults who have felt stressed, anxious, or down in the past year. Participants will attend private video sessions with a therapist and complete surveys about their mood and resilience. The goal …
Phase: NA • Sponsor: Rasa Healing Inc • Aim: Symptom relief
Last updated Jun 27, 2026 07:55 UTC
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New therapy aims to ease anxiety and depression in LGBTQ+ community hit by pandemic
Symptom relief OngoingThis study tests a short, acceptance-based therapy (ABBT) to help LGBTQ+ adults with mild anxiety or depression worsened by the COVID-19 pandemic. 240 participants will either receive the therapy or standard care. The goal is to see if ABBT can reduce symptoms and improve social …
Phase: PHASE2 • Sponsor: Brown University • Aim: Symptom relief
Last updated Jun 27, 2026 07:55 UTC
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New CBT program aims to ease anxiety in pakistani teens
Symptom relief OngoingThis study tests a 16-week cognitive behavioral therapy (CBT) program called the C.A.T Project for Pakistani teenagers aged 14 to 17 with moderate to severe anxiety. The program helps teens change unhelpful thoughts and behaviors using relaxation, problem-solving, and parent educ…
Phase: NA • Sponsor: National University of Science and Technology • Aim: Symptom relief
Last updated Jun 27, 2026 07:52 UTC
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Virtual reality hypnosis tested as Drug-Free labor pain relief
Symptom relief ENROLLING_BY_INVITATIONThis study tests whether using a virtual reality headset (HypnoVR) can help reduce pain and anxiety during labor. Seventy women in Tunis will be randomly assigned to use the headset or receive standard care. Researchers will measure pain and anxiety levels before and after the in…
Phase: NA • Sponsor: University Tunis El Manar • Aim: Symptom relief
Last updated Jun 27, 2026 07:51 UTC
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Stress balls tested as simple tool to calm nerves during prostate biopsy
Symptom relief ENROLLING_BY_INVITATIONThis study tests whether using a stress ball during a prostate biopsy can help reduce anxiety and pain. Researchers will enroll 66 men undergoing their first prostate biopsy. Participants will squeeze a stress ball during the procedure, and their pain and anxiety levels will be m…
Phase: NA • Sponsor: Hitit University • Aim: Symptom relief
Last updated Jun 27, 2026 07:51 UTC
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Laughter yoga tested as a tool to ease autism anxiety and parent stress
Symptom relief OngoingThis pilot study explores whether laughter yoga can reduce depression and anxiety in children with autism spectrum disorder (ages 8–12) and lower parenting stress for their parents. 66 families will either take part in laughter yoga sessions or be placed on a waiting list. The st…
Phase: NA • Sponsor: LAM Chung Yan Hemio • Aim: Symptom relief
Last updated Jun 26, 2026 19:11 UTC
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Earbuds that zap nerves could ease healthcare worker burnout
Symptom relief OngoingThis study tests whether a device called transcutaneous auricular vagus nerve stimulation (TaVNS) can reduce anxiety and distress in healthcare workers. Participants wear special earbuds that send gentle vibrations to stimulate the vagus nerve. Researchers will also use brain sca…
Phase: NA • Sponsor: Thomas Jefferson University • Aim: Symptom relief
Last updated Jun 26, 2026 18:20 UTC
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New online therapy aims to ease cancer Survivors' fear of recurrence
Symptom relief OngoingThis study tests an online cognitive therapy program, guided by a therapist, to help colorectal cancer survivors who have finished treatment reduce their fear of the cancer returning. The program includes educational text, exercises, and videos. Researchers will compare it to sta…
Phase: NA • Sponsor: Vejle Hospital • Aim: Symptom relief
Last updated Jun 26, 2026 16:50 UTC
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Nose spray pain relief for kids: which works best?
Symptom relief TerminatedThis study planned to compare three different medications given as nose sprays to children aged 2 to 6 years who needed stitches for a cut. The goal was to see which one worked best for pain and anxiety during the procedure. However, the trial was withdrawn before any children we…
Phase: PHASE2 • Sponsor: Nationwide Children's Hospital • Aim: Symptom relief
Last updated Jun 26, 2026 15:58 UTC
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Loved Ones' photos may help tame social anxiety fears
Knowledge-focused OngoingThis study tests whether seeing a picture of a supportive friend or family member helps people with social anxiety unlearn fear more effectively. Researchers will compare fear responses in 100 participants (50 with social anxiety, 50 healthy) after pairing threatening cues with e…
Phase: NA • Sponsor: University of California, Los Angeles • Aim: Knowledge-focused
Last updated Aug 13, 2026 00:00 UTC
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Can a smartphone app break the stigma around depression in black communities?
Knowledge-focused OngoingThis study tests a video-based mobile app designed to reduce mental health stigma and medical mistrust among Black adults with moderate to severe depression or anxiety. Participants watch personal stories from others with similar experiences. The goal is to see if this approach i…
Phase: NA • Sponsor: Massachusetts General Hospital • Aim: Knowledge-focused
Last updated Aug 13, 2026 00:00 UTC
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Could a photo of a loved one quiet fear in social anxiety?
Knowledge-focused OngoingThis study looks at whether seeing a picture of a supportive person can help people with social anxiety feel less afraid. Researchers will compare 50 healthy adults and 50 adults with social anxiety disorder. Participants will learn to associate a neutral image with a mild electr…
Phase: NA • Sponsor: University of California, Los Angeles • Aim: Knowledge-focused
Last updated Aug 13, 2026 00:00 UTC
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Study tests if pot ads lure anxious users into buying more THC
Knowledge-focused OngoingThis study looks at how cannabis ads that claim to help with anxiety or depression affect what people buy. About 2,000 light-to-moderate cannabis users with mild to severe anxiety or depression will shop in a realistic online store. Some see ads with mental health claims, others …
Phase: NA • Sponsor: Trustees of Dartmouth College • Aim: Knowledge-focused
Last updated Aug 06, 2026 00:00 UTC
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Your phone could help design your therapy: new study tests personalized CBT for anxiety and drinking
Knowledge-focused ENROLLING_BY_INVITATIONThis study uses smartphone data to understand what triggers anxiety and alcohol use in each person, then tailors therapy to those specific triggers. 81 adults with anxiety and alcohol problems will receive 11 sessions of cognitive behavioral therapy (CBT) either personalized to t…
Phase: NA • Sponsor: Rutgers, The State University of New Jersey • Aim: Knowledge-focused
Last updated Aug 01, 2026 00:00 UTC
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Can anal cancer treatment spare sexual well-being? a study tracks the toll over two years.
Knowledge-focused OngoingThis study follows people treated for anal cancer with radiotherapy to see how their sexual quality of life changes over time. Participants complete questionnaires during treatment, three months later, and two years after diagnosis. The goal is to understand the long-term impact …
Sponsor: Institut du Cancer de Montpellier - Val d'Aurelle • Aim: Knowledge-focused
Last updated Jul 30, 2026 00:00 UTC
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Could a common virus trigger mental illness? massive study investigates
Knowledge-focused OngoingThis study uses health records from about 100,000 people in Israel to see if past viral infections (like Epstein-Barr, COVID-19, or herpes) increase the risk of developing mental illnesses such as depression, anxiety, bipolar disorder, or schizophrenia. It also looks at whether i…
Sponsor: Shalvata Mental Health Center • Aim: Knowledge-focused
Last updated Jul 25, 2026 00:00 UTC
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Jaw pain and mental health: study probes the hidden link
Knowledge-focused ENROLLING_BY_INVITATIONThis study looks at adults with temporomandibular disorders (TMD) — problems with the jaw joint and muscles — to measure how chronic pain, anxiety, depression, and perceived stress relate to each other. Researchers will use standard questionnaires to assess pain severity, depress…
Sponsor: Wroclaw Medical University • Aim: Knowledge-focused
Last updated Jul 12, 2026 00:00 UTC
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Why do people grind their teeth at night? new study seeks answers
Knowledge-focused ENROLLING_BY_INVITATIONThis study looks at 50 adults with sleep bruxism (teeth grinding during sleep) to understand how it affects sleep, pain, anxiety, and overall health. Researchers will use sleep tests, blood samples, and questionnaires to find links between bruxism and other conditions. The goal i…
Sponsor: Wroclaw Medical University • Aim: Knowledge-focused
Last updated Jul 11, 2026 00:00 UTC
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Could probing the causes of pregnancy loss protect women's mental health?
Knowledge-focused OngoingThis study looks at whether women who took part in a thorough medical investigation after a pregnancy loss (the COPL cohort) had better mental health outcomes one year later compared to those who received standard care. Researchers will analyze data from Danish national registrie…
Phase: NA • Sponsor: Amager Hospital • Aim: Knowledge-focused
Last updated Jul 08, 2026 00:00 UTC
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Scientists watch the Brain's emotion network in real time
Knowledge-focused ENROLLING_BY_INVITATIONThis study investigates how the brain's emotion network works by recording brain activity directly from the surface of the brain in people with epilepsy who are already undergoing surgery for seizure monitoring. Participants watch short video clips designed to trigger emotions li…
Phase: NA • Sponsor: University of California, San Francisco • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:02 UTC
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Short walks beat one big workout for Kids' health?
Knowledge-focused OngoingThis study looks at whether taking short walks throughout the day is better for kids at risk for type 2 diabetes than one longer exercise session. Researchers will measure blood sugar, insulin, and thinking skills in 188 children aged 8-11 with overweight or obesity. The goal is …
Phase: NA • Sponsor: University of Southern California • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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Daily struggles of hispanic dementia caregivers under the microscope
Knowledge-focused OngoingThis study follows 300 Hispanic and Latino caregivers of relatives with memory problems or dementia. Participants complete daily surveys for three weeks at a time, plus follow-ups at six and twelve months, to track how their mood and stress change day-to-day. The goal is to ident…
Sponsor: University of Alabama at Birmingham • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:00 UTC
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Can tracking rigid thoughts improve addiction treatment?
Knowledge-focused ENROLLING_BY_INVITATIONThis study observes 35 people in residential treatment for substance use disorders to measure behavioral rigidity—the tendency to get stuck in inflexible thinking patterns. Participants complete weekly questionnaires and have their therapy sessions analyzed for language patterns.…
Sponsor: Lauro Gutiérrez Castro • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:35 UTC
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Counselors to the rescue: new study aims to beat doctor burnout
Knowledge-focused OngoingThis study looks at whether having a licensed counselor available can improve the mental well-being of medical residents (doctors in training). The researchers will measure changes in well-being, depression, and anxiety. 21 internal medicine residents from the University of Nevad…
Phase: NA • Sponsor: University of Nevada, Reno • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC
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Study on video calls for Alzheimer's caregivers pulled before starting
Knowledge-focused TerminatedThis study was designed to test whether scheduled video calls with a nurse could help family members who make medical decisions for hospitalized older adults with Alzheimer's or similar cognitive issues. The goal was to improve communication and reduce anxiety and depression. How…
Phase: NA • Sponsor: Indiana University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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Withdrawn study aimed to boost mental health in young south asian women
Knowledge-focused TerminatedThis study aimed to develop and test a 12-week mental health program designed specifically for young South Asian women aged 16-24 with mood or anxiety disorders. The program was meant to address cultural and gender needs. However, the study was withdrawn before any participants w…
Phase: NA • Sponsor: Centre for Addiction and Mental Health • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:07 UTC
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New mHealth program aims to lower depression and stress in black pregnant women
Knowledge-focused OngoingThis study tests whether a culturally tailored mobile health program can improve mental health and pregnancy outcomes in Black pregnant women. Half of the 150 participants will receive the program, which builds communication and self-advocacy skills and provides support. The goal…
Phase: PHASE2, PHASE3 • Sponsor: Cedars-Sinai Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:05 UTC
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Jaw surgery study reveals hidden emotional and muscle changes
Knowledge-focused ENROLLING_BY_INVITATIONThis study looks at how jaw surgery changes not just your bite and appearance, but also your emotions, jaw muscles, and joint health. Researchers will follow 100 patients before and after surgery, using scans, muscle tests, and questionnaires to track these changes. The goal is t…
Phase: NA • Sponsor: Lithuanian University of Health Sciences • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:03 UTC
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New eLearning platform aims to train therapists in exposure therapy
Knowledge-focused ENROLLING_BY_INVITATIONThis study is developing and testing an online training program to teach therapists how to deliver exposure therapy to people with anxiety disorders and OCD. About 56 practicing therapists will try the program and give feedback to improve it. The goal is to see if the training re…
Phase: NA • Sponsor: Bradley Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:01 UTC
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Holistic education study for stress withdrawn before starting
Knowledge-focused TerminatedThis study was designed to test a holistic education program for stress management in people from colonized English-speaking countries. It aimed to help with conditions like stress, PTSD, anxiety, and fatigue using pastoral counseling and self-care activities. However, the study …
Phase: NA • Sponsor: Goddess Zena I. Jones • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:01 UTC
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Which therapy works best for troubled teens? new study aims to find out
Knowledge-focused ENROLLING_BY_INVITATIONThis study follows 192 teens aged 12 to 20 who are already receiving either Cognitive Behavioral Therapy (CBT) or Brief Strategic Therapy (BST) for anxiety, depression, or OCD. Researchers will track their progress using questionnaires and interviews over 9 months. The goal is to…
Sponsor: IRCCS Centro Neurolesi Bonino Pulejo • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:01 UTC
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Could a brain chemical blocker prevent Stress-Linked depression?
Knowledge-focused TerminatedThis study aimed to see if a drug called LY-2940094 could protect healthy adults from developing depression- or anxiety-like symptoms after stress. Researchers planned to give the drug to participants and then measure their brain responses to rewards and fear. However, the trial …
Phase: PHASE2 • Sponsor: Mclean Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:51 UTC
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Physios' hidden role in mental health: new study explores screening for anxiety and depression
Knowledge-focused OngoingThis study interviews 18 physiotherapists in private practice to understand how they screen for anxiety and depression in patients with chronic neck, shoulder, and low back pain. The goal is to identify what helps or hinders these mental health checks. The study does not test any…
Sponsor: Ana Catarina Navarro Ramalho • Aim: Knowledge-focused
Last updated Jun 26, 2026 18:06 UTC