MULTIPLE SCLEROSIS
Clinical trials for MULTIPLE SCLEROSIS explained in plain language.
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Plasma swap shows promise for tough MS Flare-Ups
Disease control CompletedThis study tested whether plasma exchange (a procedure that cleans the blood) helps people with multiple sclerosis (MS) who have a relapse that doesn't get better with steroids. 38 adults with MS took part. The goal was to see if this treatment improves disability after one month…
Matched conditions: MULTIPLE SCLEROSIS
Phase: PHASE3 • Sponsor: University Hospital, Bordeaux • Aim: Disease control
Last updated May 26, 2026 01:24 UTC
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MS drug ocrelizumab shows promise in Long-Term extension trial
Disease control CompletedThis study looked at how well and how safely the drug ocrelizumab works over a longer period for people with multiple sclerosis (MS). It included over 1,000 participants who had already been in earlier Roche studies of ocrelizumab. The goal was to track disability changes, relaps…
Matched conditions: MULTIPLE SCLEROSIS
Phase: PHASE3 • Sponsor: Hoffmann-La Roche • Aim: Disease control
Last updated May 26, 2026 01:23 UTC
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Brain scans reveal Ocrelizumab's impact on MS inflammation
Disease control CompletedThis study looked at how the drug ocrelizumab changes brain inflammation in people with multiple sclerosis (MS). Researchers used special brain scans to measure inflammation before and after one year of treatment. The study included 22 adults with relapsing-remitting or progressi…
Matched conditions: MULTIPLE SCLEROSIS
Phase: PHASE4 • Sponsor: Massachusetts General Hospital • Aim: Disease control
Last updated May 26, 2026 01:16 UTC
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Could a diabetes drug and an antihistamine help repair MS nerve damage?
Disease control CompletedThis study tested whether combining two common drugs—metformin (for diabetes) and clemastine (an antihistamine)—can help repair the protective lining around nerve cells in people with relapsing-remitting multiple sclerosis (MS). The 70 participants continued their usual MS treatm…
Matched conditions: MULTIPLE SCLEROSIS
Phase: PHASE2 • Sponsor: Cambridge University Hospitals NHS Foundation Trust • Aim: Disease control
Last updated May 26, 2026 01:16 UTC
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New monthly MS shot challenges standard pills in Head-to-Head trial
Disease control CompletedThis study tested a monthly injection called ofatumumab against standard daily or weekly pills for people newly diagnosed with relapsing multiple sclerosis (MS). The goal was to see which treatment better controls the disease by preventing relapses, new brain lesions, and worseni…
Matched conditions: MULTIPLE SCLEROSIS
Phase: PHASE3 • Sponsor: Novartis Pharmaceuticals • Aim: Disease control
Last updated May 22, 2026 14:04 UTC
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Gold nanoparticles aim to rev up brain cells in MS patients
Disease control CompletedThis study tested a new drug called CNM-Au8, made of tiny gold particles, in 33 adults with relapsing multiple sclerosis (MS). The goal was to see if it could improve energy use in brain cells, measured by a special MRI scan. Participants took the drug for 12 weeks while continui…
Matched conditions: MULTIPLE SCLEROSIS
Phase: PHASE2 • Sponsor: Clene Nanomedicine • Aim: Disease control
Last updated May 22, 2026 13:53 UTC
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New hope for MS patients: cladribine tablets studied after other treatments fail
Disease control CompletedThis study tested cladribine tablets in 291 adults with relapsing forms of multiple sclerosis (MS) who had not done well on other oral or infusion medications. The goal was to see if switching to cladribine could reduce relapses and improve patient satisfaction. Results showed ho…
Matched conditions: MULTIPLE SCLEROSIS
Sponsor: EMD Serono Research & Development Institute, Inc. • Aim: Disease control
Last updated May 22, 2026 13:51 UTC
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Real-World study confirms Ocrelizumab's benefits for MS patients
Disease control CompletedThis study followed over 1,700 people with relapsing or progressive multiple sclerosis who were prescribed ocrelizumab as part of their normal care. Researchers tracked changes in symptoms like mobility, fatigue, and cognition, as well as side effects and quality of life. The goa…
Matched conditions: MULTIPLE SCLEROSIS
Sponsor: Hoffmann-La Roche • Aim: Disease control
Last updated May 22, 2026 13:50 UTC
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Could a common gut acid help control multiple sclerosis?
Disease control CompletedThis study tested whether propionic acid, a natural substance, is safe and helpful for people with multiple sclerosis (MS) when added to their usual treatment. 22 adults with stable MS took propionic acid for a year. Researchers measured nerve damage markers and thinking speed to…
Matched conditions: MULTIPLE SCLEROSIS
Phase: PHASE2, PHASE3 • Sponsor: Salzburger Landeskliniken • Aim: Disease control
Last updated May 20, 2026 11:58 UTC
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Kesimpta shows promise in controlling MS in swiss study
Disease control CompletedThis study observed 107 Swiss adults with relapsing multiple sclerosis who were already taking Kesimpta (ofatumumab) for at least 3 months. Researchers tracked how well the drug controlled their disease, looking for signs like relapses, new brain lesions, or worsening disability.…
Matched conditions: MULTIPLE SCLEROSIS
Sponsor: Novartis Pharmaceuticals • Aim: Disease control
Last updated May 20, 2026 11:57 UTC
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Blood filtering therapy shows promise for MS in small trial
Disease control CompletedThis early-phase study tested a treatment called extracorporeal photopheresis (ECP) in 15 people with multiple sclerosis (MS). ECP involves filtering a person's blood, treating it with light, and returning it to the body. The goal was to see if it is safe and might help improve w…
Matched conditions: MULTIPLE SCLEROSIS
Phase: PHASE1, PHASE2 • Sponsor: Abu Dhabi Stem Cells Center • Aim: Disease control
Last updated May 20, 2026 11:53 UTC
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Own stem cells tested against MS in new trial
Disease control CompletedThis study tested whether a person's own stem cells (called HB-adMSCs) could improve quality of life for people with multiple sclerosis. 24 adults with relapsing-remitting MS received either the stem cells or a placebo through 6 infusions over a year. The main goal was to see if …
Matched conditions: MULTIPLE SCLEROSIS
Phase: PHASE2 • Sponsor: Hope Biosciences Research Foundation • Aim: Disease control
Last updated Apr 26, 2026 20:02 UTC
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New Gadolinium-Free MRI dye shows promise for brain lesion detection
Diagnosis CompletedThis study tested a new MRI contrast agent called RVP-001 in 18 adults with brain lesions from conditions like tumors or multiple sclerosis. The goal was to see if it is safe and effective at highlighting these lesions without using gadolinium, a metal that can build up in the bo…
Matched conditions: MULTIPLE SCLEROSIS
Phase: PHASE2 • Sponsor: Reveal Pharmaceuticals Inc. • Aim: Diagnosis
Last updated May 26, 2026 01:17 UTC
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Eye-Tracking gadget could help gauge MS severity
Diagnosis CompletedThis study tested a device called ETNA-MS that uses eye-tracking to estimate disability levels in people with Multiple Sclerosis (MS). 60 adults with MS took part. The goal was to see how well the device's results matched the standard exam done by a neurologist. If accurate, this…
Matched conditions: MULTIPLE SCLEROSIS
Sponsor: Innodem Neurosciences • Aim: Diagnosis
Last updated May 20, 2026 11:55 UTC
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Virtual reality training shows promise for MS arm weakness
Symptom relief CompletedThis study tested whether watching 3D virtual reality videos of arm movements could help people with multiple sclerosis (MS) improve their hand and arm function. Thirty-two people with MS who had arm weakness took part. They watched and imitated the movements, and researchers mea…
Matched conditions: MULTIPLE SCLEROSIS
Phase: NA • Sponsor: Abant Izzet Baysal University • Aim: Symptom relief
Last updated May 26, 2026 01:28 UTC
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Can simple pelvic floor exercises ease bladder troubles for women with MS?
Symptom relief CompletedThis study tested whether pelvic floor strengthening or relaxation exercises, done at home with online guidance, could help women with multiple sclerosis who have bladder control issues. Twenty-four women took part in 8 weeks of weekly online sessions and daily exercises. The goa…
Matched conditions: MULTIPLE SCLEROSIS
Phase: NA • Sponsor: Gazi University • Aim: Symptom relief
Last updated May 26, 2026 01:28 UTC
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Can online exercise classes help MS patients feel better?
Symptom relief CompletedThis study tested two types of remote exercise programs for people with relapsing-remitting multiple sclerosis. Sixteen participants either joined live online classes or followed pre-recorded videos. The goal was to see which method better improves walking, strength, fatigue, and…
Matched conditions: MULTIPLE SCLEROSIS
Phase: NA • Sponsor: Yeditepe University • Aim: Symptom relief
Last updated May 26, 2026 01:28 UTC
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Chill out: cold therapy tested for MS fatigue
Symptom relief CompletedThis study looked at whether partial-body cryotherapy (brief exposure to extreme cold) can reduce fatigue in people with multiple sclerosis during a rehabilitation stay. 43 adults with MS in remission took part. The main goal was to measure changes in fatigue severity using a sta…
Matched conditions: MULTIPLE SCLEROSIS
Phase: NA • Sponsor: Fondation Ildys • Aim: Symptom relief
Last updated May 26, 2026 01:28 UTC
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Pilates shows promise for improving balance in MS patients
Symptom relief CompletedThis study looked at whether doing Pilates (on a mat or using a reformer machine) twice a week for eight weeks could help people with multiple sclerosis (MS) improve their balance, walking, and posture. Thirty adults with MS took part. The goal was to see if these exercises could…
Matched conditions: MULTIPLE SCLEROSIS
Phase: NA • Sponsor: Gazi University • Aim: Symptom relief
Last updated May 26, 2026 01:27 UTC
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Shock waves may boost balance in MS patients
Symptom relief CompletedThis study tested a treatment called extracorporeal shock wave therapy (ESWT) in 54 people with multiple sclerosis. The goal was to see if it could improve foot sensation, balance, and walking. Participants received ESWT three times a week for six weeks, and the researchers measu…
Matched conditions: MULTIPLE SCLEROSIS
Phase: NA • Sponsor: Furkan Bilek • Aim: Symptom relief
Last updated May 26, 2026 01:27 UTC
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Which MS shot hurts less? new study compares kesimpta and ocrevus
Symptom relief CompletedThis study looked at how people with multiple sclerosis felt about their first injection of either Kesimpta or a new under-the-skin version of Ocrevus. 134 adults who were just starting one of these drugs answered questions about pain, redness, swelling, and itching at the inject…
Matched conditions: MULTIPLE SCLEROSIS
Sponsor: Novartis Pharmaceuticals • Aim: Symptom relief
Last updated May 26, 2026 01:26 UTC
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MS fatigue: does this supplement actually work?
Symptom relief CompletedThis study tested whether L-carnitine, a natural supplement, can reduce fatigue in people with multiple sclerosis. 59 adults with MS and significant fatigue took either L-carnitine or a placebo in a crossover design. The main goal was to see if L-carnitine improved fatigue scores…
Matched conditions: MULTIPLE SCLEROSIS
Phase: PHASE3 • Sponsor: University Hospital, Bordeaux • Aim: Symptom relief
Last updated May 26, 2026 01:26 UTC
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New online program helps MS patients stay on their feet
Symptom relief CompletedThis study tested a new online program to help people with multiple sclerosis prevent falls. The program taught self-management strategies to reduce fall risks. 45 adults with MS took part. The goal was to see if the program was easy to use and helpful.
Matched conditions: MULTIPLE SCLEROSIS
Phase: NA • Sponsor: Karolinska Institutet • Aim: Symptom relief
Last updated May 26, 2026 01:26 UTC
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Can a home exercise program help Hispanics/Latinos with MS?
Symptom relief CompletedThis study tested whether a 4-month exercise program done at home could help Hispanics/Latinos with multiple sclerosis (MS) feel better and move easier. Participants worked with coaches via video calls to do flexibility, aerobic, and resistance exercises. The goal was to see if t…
Matched conditions: MULTIPLE SCLEROSIS
Phase: NA • Sponsor: University of Illinois at Chicago • Aim: Symptom relief
Last updated May 26, 2026 01:26 UTC
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New exercise combo shows promise for bladder issues in MS patients
Symptom relief CompletedThis study looked at whether adding Dynamic Neuromuscular Stabilization (DNS) exercises to standard pelvic floor muscle training can better improve bladder symptoms and pelvic muscle function in women with multiple sclerosis. Twenty-four women aged 28-54 completed an 8-week progr…
Matched conditions: MULTIPLE SCLEROSIS
Phase: NA • Sponsor: Ondokuz Mayıs University • Aim: Symptom relief
Last updated May 26, 2026 01:25 UTC
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At-Home voice therapy shows promise for MS patients
Symptom relief CompletedThis study tested whether a voice treatment called LSVT-Loud, usually done in a clinic, could work when done at home via video calls for people with multiple sclerosis (MS). Twenty adults with MS who had voice problems took part. The goal was to see if the at-home approach could …
Matched conditions: MULTIPLE SCLEROSIS
Phase: NA • Sponsor: Fondazione Don Carlo Gnocchi Onlus • Aim: Symptom relief
Last updated May 26, 2026 01:25 UTC
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Move to the beat: exercise study shows promise for disability fitness
Symptom relief CompletedThis study tested a 12-week exercise program set to music for 108 adults with physical disabilities like spinal cord injury, stroke, or Parkinson's disease. Participants were split into two groups: one did the music-based exercise, the other waited. The goal was to see if this fu…
Matched conditions: MULTIPLE SCLEROSIS
Phase: NA • Sponsor: University of Alabama at Birmingham • Aim: Symptom relief
Last updated May 26, 2026 01:25 UTC
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Acupressure shows promise for easing MS symptoms
Symptom relief CompletedThis study looked at whether acupressure, a technique where pressure is applied to specific points on the body, can help people with multiple sclerosis (MS) manage pain, fatigue, sleep problems, and improve quality of life. Researchers enrolled 90 adults with MS who had significa…
Matched conditions: MULTIPLE SCLEROSIS
Phase: NA • Sponsor: Hasan Kalyoncu University • Aim: Symptom relief
Last updated May 26, 2026 01:24 UTC
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Mind over MS: brain retraining shows promise for symptom relief
Symptom relief CompletedThis study tested whether a lifestyle program and a mind-body brain retraining program could help people with multiple sclerosis feel better. 132 participants were split into groups to try these programs or stay on a waitlist. The goal was to see if these approaches could reduce …
Matched conditions: MULTIPLE SCLEROSIS
Phase: NA • Sponsor: Chronic Conditions Research Fund • Aim: Symptom relief
Last updated May 26, 2026 01:24 UTC
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8-Week aerobic program boosts mobility in MS patients
Symptom relief CompletedThis study looked at whether 8 weeks of aerobic exercise can improve movement and walking in people with multiple sclerosis (MS). 30 adults with MS were randomly assigned to either an exercise group or a control group. The exercise group showed significant improvements in walking…
Matched conditions: MULTIPLE SCLEROSIS
Phase: NA • Sponsor: Lokman Hekim University • Aim: Symptom relief
Last updated May 26, 2026 01:24 UTC
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Light at the end of the tunnel: bright light therapy may ease MS sleep problems
Symptom relief CompletedThis small pilot study tested whether bright light therapy can reduce sleep problems in people with multiple sclerosis (MS). 27 adults with MS and sleep issues used a bright light device. The goal was to see if the light improves sleep and daily function by helping regulate the b…
Matched conditions: MULTIPLE SCLEROSIS
Phase: NA • Sponsor: Johns Hopkins University • Aim: Symptom relief
Last updated May 26, 2026 01:23 UTC
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Probiotic drink trial for MS: small study tests gut health impact
Symptom relief CompletedThis study tested whether it is practical and acceptable for people with multiple sclerosis (MS) to take a probiotic drink daily for 12 weeks. Twenty-nine adults with MS drank 70 ml of a probiotic each day and completed online questionnaires, cognitive tests, and stool samples. T…
Matched conditions: MULTIPLE SCLEROSIS
Phase: NA • Sponsor: Sheffield Hallam University • Aim: Symptom relief
Last updated May 26, 2026 01:22 UTC
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New app aims to boost MS Patients' daily life
Symptom relief CompletedThis study tested a new Arabic mobile app designed to help people with multiple sclerosis (MS) improve their self-care and quality of life. 74 adults with MS used either the app or received usual care for 3 months. Researchers measured changes in self-care habits and overall well…
Matched conditions: MULTIPLE SCLEROSIS
Phase: NA • Sponsor: Cairo University • Aim: Symptom relief
Last updated May 26, 2026 01:21 UTC
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Video workouts may loosen stiff legs in MS patients
Symptom relief CompletedThis study tested two different group exercise programs delivered by video call to help people with multiple sclerosis manage leg spasticity (muscle stiffness). 232 participants with MS who had leg spasticity interfering with daily life took part. The goal was to see which progra…
Matched conditions: MULTIPLE SCLEROSIS
Phase: NA • Sponsor: VA Office of Research and Development • Aim: Symptom relief
Last updated May 26, 2026 01:21 UTC
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New combo therapy aims to boost brain function and quality of life
Symptom relief CompletedThis study tested whether a program that combines talk therapy, brain training exercises, and healthy lifestyle coaching is practical and helpful for people with mild cognitive impairment, traumatic brain injury, multiple sclerosis, or long COVID. Fifteen participants received th…
Matched conditions: MULTIPLE SCLEROSIS
Phase: NA • Sponsor: University of Michigan • Aim: Symptom relief
Last updated May 26, 2026 01:21 UTC
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Robot suit helps MS patients walk again – small trial shows promise
Symptom relief CompletedThis study tested whether a self-balancing robotic exoskeleton called Atalante is safe and easy to use for people with multiple sclerosis (MS) who have trouble walking. Fifteen adults with MS used the device during therapy sessions. The main goal was to see if patients found it u…
Matched conditions: MULTIPLE SCLEROSIS
Phase: NA • Sponsor: Multiple Sclerosis Center of Catalonia • Aim: Symptom relief
Last updated May 26, 2026 01:19 UTC
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Smartphone app helps MS patients get stronger at home
Symptom relief CompletedThis study tested whether an artificial intelligence (AI) app could help people with multiple sclerosis (MS) do strength exercises at home better than traditional paper instructions. Fifty-eight adults with MS followed a 20-week strength training program. One group used an AI app…
Matched conditions: MULTIPLE SCLEROSIS
Phase: NA • Sponsor: University of Cadiz • Aim: Symptom relief
Last updated May 26, 2026 01:18 UTC
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Mind and body combo boosts mobility in MS patients
Symptom relief CompletedThis study looked at whether adding cognitive behavior therapy (a type of talk therapy) to supervised Pilates exercises could help people with multiple sclerosis walk better and keep their balance. Ninety adults with mild to moderate MS took part. The goal was to see if the combi…
Matched conditions: MULTIPLE SCLEROSIS
Phase: NA • Sponsor: Cairo University • Aim: Symptom relief
Last updated May 26, 2026 01:17 UTC
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Wheelchair workout study shows promise for MS symptoms
Symptom relief CompletedThis study tested a 16-week exercise program designed for wheelchair users with multiple sclerosis. Researchers wanted to see if the program was safe, doable, and could improve MS symptoms and metabolic health. Twenty-four participants were randomly assigned to either the exercis…
Matched conditions: MULTIPLE SCLEROSIS
Phase: NA • Sponsor: The University of Texas Health Science Center, Houston • Aim: Symptom relief
Last updated May 26, 2026 01:16 UTC
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Laughter yoga shows promise for MS fatigue and sleep troubles
Symptom relief CompletedThis study looked at whether laughter yoga can help people with multiple sclerosis (MS) feel less tired, sleep better, and improve their overall mood. Forty adults with MS took part, and the researchers measured their fatigue, sleep quality, and psychological well-being before an…
Matched conditions: MULTIPLE SCLEROSIS
Phase: NA • Sponsor: Tokat Gaziosmanpasa University • Aim: Symptom relief
Last updated May 26, 2026 01:16 UTC
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Walking faster to feel better: High-Intensity gait training shows promise for MS fatigue
Symptom relief CompletedThis study looked at whether high-intensity walking exercise can reduce fatigue and improve walking in people with multiple sclerosis (MS). Twelve adults with MS who had walking difficulties and significant fatigue took part. They completed a high-intensity gait training program,…
Matched conditions: MULTIPLE SCLEROSIS
Phase: NA • Sponsor: University of Illinois at Chicago • Aim: Symptom relief
Last updated May 26, 2026 01:16 UTC
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Water workouts may ease MS fatigue and balance issues
Symptom relief CompletedThis study looked at whether a water-based exercise program (hydrotherapy) could help improve balance and reduce fatigue in people with multiple sclerosis. 26 adults with relapsing-remitting MS took part in 16 hydrotherapy sessions. Researchers measured changes in balance and fat…
Matched conditions: MULTIPLE SCLEROSIS
Phase: NA • Sponsor: University of Thessaly • Aim: Symptom relief
Last updated May 26, 2026 01:15 UTC
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Zapping the brain to ease MS symptoms: a new hope?
Symptom relief CompletedThis study tested whether repeated electrical brain stimulation could help with mental health and thinking problems in people with multiple sclerosis (MS). 53 adults with MS took part in a double-blind trial where some received the stimulation and others did not. The goal was to …
Matched conditions: MULTIPLE SCLEROSIS
Phase: NA • Sponsor: The National Brain Mapping Laboratory (NBML) • Aim: Symptom relief
Last updated May 22, 2026 14:04 UTC
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Can talk therapy tame MS fatigue? new study says maybe
Symptom relief CompletedThis study looked at whether three types of cognitive behavioral therapy (relaxation, activity planning, and changing thoughts) delivered by video call could help with fatigue in people with multiple sclerosis. 21 adults with MS and chronic fatigue took part. The main goal was to…
Matched conditions: MULTIPLE SCLEROSIS
Phase: NA • Sponsor: University of Washington • Aim: Symptom relief
Last updated May 22, 2026 14:04 UTC
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Robot suit may help MS patients walk faster than traditional therapy
Symptom relief CompletedThis study tested whether a self-balancing robotic exoskeleton (Atalante) can improve walking speed in people with multiple sclerosis better than standard rehabilitation. Sixty participants with moderate to severe walking difficulty were randomly assigned to 24 sessions of either…
Matched conditions: MULTIPLE SCLEROSIS
Phase: NA • Sponsor: Multiple Sclerosis Center of Catalonia • Aim: Symptom relief
Last updated May 22, 2026 14:02 UTC
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Brain games and light exercise aim to sharpen MS minds
Symptom relief CompletedThis study tested two different computer-based brain training programs, combined with light physical activity, to see if they could improve thinking skills like memory and attention in people with multiple sclerosis (MS). Forty adults with MS who had some cognitive complaints too…
Matched conditions: MULTIPLE SCLEROSIS
Phase: NA • Sponsor: University of California, San Francisco • Aim: Symptom relief
Last updated May 22, 2026 13:59 UTC
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New online therapy eases anxiety and depression in MS patients
Symptom relief CompletedThis study tested an 8-week online program to help people with multiple sclerosis (MS) improve their problem-solving and coping skills. The goal was to see if the program was easy to use and if it could reduce anxiety and depression. Thirty adults with MS in Lebanon took part. Th…
Matched conditions: MULTIPLE SCLEROSIS
Phase: NA • Sponsor: American University of Beirut Medical Center • Aim: Symptom relief
Last updated May 22, 2026 13:55 UTC
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Simple exercises may ease bladder problems in women with MS
Symptom relief CompletedThis study tested whether a special pelvic floor muscle exercise program, based on the Health Belief Model, could help reduce urinary incontinence and improve quality of life in women with multiple sclerosis. 46 women completed the 3-month program. The goal was to see if these ex…
Matched conditions: MULTIPLE SCLEROSIS
Phase: NA • Sponsor: Nurgül KAPLAN • Aim: Symptom relief
Last updated May 22, 2026 13:52 UTC
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Gratitude letters boost mood in new MS patients, small study finds
Symptom relief CompletedThis study tested whether doing simple positive psychology exercises—like writing a thank-you letter or recalling a past success—could help people recently diagnosed with multiple sclerosis (MS) feel more hopeful and improve their quality of life. Thirty adults with MS diagnosed …
Matched conditions: MULTIPLE SCLEROSIS
Phase: NA • Sponsor: Brigham and Women's Hospital • Aim: Symptom relief
Last updated May 22, 2026 13:50 UTC
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Can a computer help MS patients exercise better at home?
Symptom relief CompletedThis study tested whether a home computer system could help veterans with multiple sclerosis do physical therapy exercises on their own. 51 participants used the system to track their exercises and monitor their balance and strength. The goal was to see if this approach was pract…
Matched conditions: MULTIPLE SCLEROSIS
Phase: NA • Sponsor: University of Maryland, Baltimore • Aim: Symptom relief
Last updated May 20, 2026 12:08 UTC
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Mind over MS: imagining movement boosts walking in small trial
Symptom relief CompletedThis study tested whether adding mental practice (imagining or watching movements) to standard physical therapy helps people with multiple sclerosis. 48 adults with mild disability (able to walk without aid) took part. The goal was to see if these techniques improve walking dista…
Matched conditions: MULTIPLE SCLEROSIS
Phase: NA • Sponsor: Hacettepe University • Aim: Symptom relief
Last updated May 20, 2026 11:56 UTC
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Online program cuts falls in MS patients
Symptom relief CompletedThis study tested a digital group program called 'Fewer Falls in MS' to help people with multiple sclerosis prevent falls. 240 participants who could walk or transfer independently and had fallen in the past year took part. The program included eight online sessions and home exer…
Matched conditions: MULTIPLE SCLEROSIS
Phase: NA • Sponsor: Karolinska Institutet • Aim: Symptom relief
Last updated May 20, 2026 11:56 UTC
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Brain zaps and puzzles may sharpen MS minds
Symptom relief CompletedThis study tested whether a gentle brain stimulation technique (tDCS) combined with computer-based cognitive training can improve memory, attention, and brain flexibility in people with multiple sclerosis (MS). 45 adults with MS took part. The goal was to see if these non-invasiv…
Matched conditions: MULTIPLE SCLEROSIS
Phase: NA • Sponsor: Shahid Beheshti University of Medical Sciences • Aim: Symptom relief
Last updated May 20, 2026 11:56 UTC
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Can zapping nerves boost hand strength in MS?
Symptom relief CompletedThis study tested two types of electrical nerve stimulation—one using tiny needles and one using skin pads—to see if they could improve hand function in people with multiple sclerosis. Twenty-eight adults with MS received one session of each method, and their hand dexterity, stre…
Matched conditions: MULTIPLE SCLEROSIS
Phase: NA • Sponsor: Universidad de Burgos • Aim: Symptom relief
Last updated May 20, 2026 11:56 UTC
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Virtual reality cycling may sharpen MS minds
Symptom relief CompletedThis study looked at whether one session of moderate cycling with virtual reality can help people with multiple sclerosis (MS) think faster. 23 adults with MS and mild-to-moderate walking problems took part. They did a cycling workout while using different types of virtual realit…
Matched conditions: MULTIPLE SCLEROSIS
Phase: NA • Sponsor: Kessler Foundation • Aim: Symptom relief
Last updated May 20, 2026 11:54 UTC
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Shocking swallowing study: could electrical stimulation help MS patients?
Symptom relief CompletedThis study tested whether adding a mild electrical stimulation to standard swallowing exercises helps people with multiple sclerosis who have trouble swallowing. 136 participants received either real or fake stimulation along with their therapy. The goal was to see if the electri…
Matched conditions: MULTIPLE SCLEROSIS
Phase: NA • Sponsor: I.R.C.C.S. Fondazione Santa Lucia • Aim: Symptom relief
Last updated May 19, 2026 11:59 UTC
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Can VR boxing help MS patients? tiny study says maybe
Symptom relief CompletedThis study tested whether a short, high-intensity virtual reality boxing program is safe and doable for people with multiple sclerosis. Five participants from a patient association in Spain used a VR headset for 10-minute sessions twice a week for 8 weeks, alongside their usual r…
Matched conditions: MULTIPLE SCLEROSIS
Phase: NA • Sponsor: University of Vigo • Aim: Symptom relief
Last updated May 19, 2026 11:48 UTC
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Shocking bladder troubles away: nerve zaps ease MS symptoms
Symptom relief CompletedThis study tested two non-invasive nerve stimulation methods—one on the ankle and one on the lower back—to help women with multiple sclerosis who have overactive bladder symptoms like frequent urination and leakage. 42 women participated, and researchers measured changes in bladd…
Matched conditions: MULTIPLE SCLEROSIS
Phase: NA • Sponsor: Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization • Aim: Symptom relief
Last updated May 19, 2026 11:47 UTC
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Can yoga or physical therapy ease MS symptoms? small study finds out
Symptom relief CompletedThis study tested whether an 8-week yoga program or standard physical therapy helps people with multiple sclerosis feel less tired, walk better, and improve their quality of life. Twenty adults with MS were split into two groups and did supervised sessions three times a week. The…
Matched conditions: MULTIPLE SCLEROSIS
Phase: NA • Sponsor: Istanbul Rumeli University • Aim: Symptom relief
Last updated May 18, 2026 12:10 UTC
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Double-Duty training shows promise for MS symptoms
Symptom relief CompletedThis study looked at whether training that combines physical and mental tasks (like walking while counting) can improve balance, walking, thinking, and fatigue in people with multiple sclerosis. Twenty-six adults with MS took part. The goal was to see if this type of training hel…
Matched conditions: MULTIPLE SCLEROSIS
Phase: NA • Sponsor: Ege University • Aim: Symptom relief
Last updated May 15, 2026 11:57 UTC
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Can a phone app help MS patients ease fatigue and pain at home?
Symptom relief CompletedThis study tested how easy and useful the MeTime MS app is for adults with multiple sclerosis who have fatigue and chronic pain. Ten participants used the app to guide them through either a relaxing or stimulating acupressure routine at home. After six weeks, researchers intervie…
Matched conditions: MULTIPLE SCLEROSIS
Phase: NA • Sponsor: University of Michigan • Aim: Symptom relief
Last updated May 15, 2026 11:53 UTC
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Can a supplement beat MS fatigue? new study tests MitoQ
Symptom relief CompletedThis study looked at whether MitoQ, a dietary supplement, can help reduce fatigue in people with multiple sclerosis (MS). 45 participants with MS and significant fatigue took either MitoQ or a placebo daily for 12 weeks. The main goal was to see if MitoQ improved fatigue scores c…
Matched conditions: MULTIPLE SCLEROSIS
Phase: PHASE1, PHASE2 • Sponsor: VA Office of Research and Development • Aim: Symptom relief
Last updated May 13, 2026 16:00 UTC
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MIND diet shows promise for easing MS fatigue and brain fog
Symptom relief CompletedThis study tested whether the MIND diet (a mix of the Mediterranean and DASH diets) can improve fatigue, brain fog, and quality of life in people with multiple sclerosis (MS). 62 adults with MS followed either the MIND diet or a standard healthy diet for 3 months. Researchers mea…
Matched conditions: MULTIPLE SCLEROSIS
Phase: NA • Sponsor: Betul Uner • Aim: Symptom relief
Last updated May 11, 2026 20:38 UTC
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Scientists uncover the secret behind arm swinging during walks
Knowledge-focused CompletedThis study investigates why humans swing their arms when walking, a common but poorly understood movement. Researchers observed 25 people, including healthy volunteers and those with conditions like multiple sclerosis or stroke, walking on a special treadmill. The goal is to lear…
Matched conditions: MULTIPLE SCLEROSIS
Sponsor: Istituto Auxologico Italiano • Aim: Knowledge-focused
Last updated May 26, 2026 01:28 UTC
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Scientists track experimental MS Drug's path through healthy men
Knowledge-focused CompletedThis study looked at how healthy men process a single dose of an experimental drug for multiple sclerosis. Six men took a radioactive-labeled version of the drug so researchers could measure how much left the body in urine and stool, and how the drug was broken down. The main goa…
Matched conditions: MULTIPLE SCLEROSIS
Phase: PHASE1 • Sponsor: Sanofi • Aim: Knowledge-focused
Last updated May 26, 2026 01:28 UTC
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New MRI methods could sharpen MS diagnosis
Knowledge-focused CompletedThis study tested two different MRI scan methods to see how well they detect the 'central vein sign,' a marker of multiple sclerosis (MS). Researchers compared a standard scan to a newer, faster version in 60 adults with early-stage MS. The goal was to find which technique works …
Matched conditions: MULTIPLE SCLEROSIS
Sponsor: Fondation Ophtalmologique Adolphe de Rothschild • Aim: Knowledge-focused
Last updated May 26, 2026 01:27 UTC
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Study reveals COVID-19 vaccine response in immunocompromised patients
Knowledge-focused CompletedThis study looked at how well the Pfizer COVID-19 vaccine triggered an immune response in 196 adults with weakened immune systems (like kidney transplant patients or those with cancer) compared to healthy adults. Researchers measured antibody levels in the blood and nose to see i…
Matched conditions: MULTIPLE SCLEROSIS
Phase: PHASE4 • Sponsor: Centre Hospitalier Régional d'Orléans • Aim: Knowledge-focused
Last updated May 26, 2026 01:26 UTC
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Lockdowns worsened health habits for chronic disease patients, study finds
Knowledge-focused CompletedThis study examined how COVID-19 lockdowns impacted over 1,300 people with chronic conditions like heart disease, multiple sclerosis, and hemophilia. Researchers looked at changes in medication use, lifestyle habits, and stress levels. The goal was to understand the health risks …
Matched conditions: MULTIPLE SCLEROSIS
Sponsor: Centre Hospitalier Universitaire Dijon • Aim: Knowledge-focused
Last updated May 26, 2026 01:26 UTC
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Healthy men test drug interactions for MS treatment
Knowledge-focused CompletedThis study looked at how two common drugs, gemfibrozil and rifampicin, change the way the body processes a potential multiple sclerosis medicine called SAR442168. Thirty healthy men aged 18 to 45 took part. The goal was to gather safety and drug-level information, not to treat an…
Matched conditions: MULTIPLE SCLEROSIS
Phase: PHASE1 • Sponsor: Sanofi • Aim: Knowledge-focused
Last updated May 26, 2026 01:25 UTC
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New tools aim to catch MS nerve damage earlier
Knowledge-focused CompletedThis study followed 134 people who had a first episode of neurological symptoms (clinically isolated syndrome) that could lead to multiple sclerosis. The goal was to develop better ways to detect and monitor nerve damage early using MRI and eye exams. By identifying those at high…
Matched conditions: MULTIPLE SCLEROSIS
Sponsor: University Hospital, Lille • Aim: Knowledge-focused
Last updated May 26, 2026 01:25 UTC
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Brain scans reveal best exercise for MS patients
Knowledge-focused CompletedThis study looked at how different types of exercise—standard, conservative aerobic, and virtual reality-based aerobic—affect the brain and body in people with multiple sclerosis. Twelve participants completed each exercise type at two-week intervals while researchers measured br…
Matched conditions: MULTIPLE SCLEROSIS
Phase: NA • Sponsor: Acibadem University • Aim: Knowledge-focused
Last updated May 26, 2026 01:25 UTC
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MS fatigue mystery: scientists hunt for immune cell link
Knowledge-focused CompletedThis study looked at whether a certain type of immune cell (cytotoxic CD4+ T cells) is connected to fatigue in people with multiple sclerosis (MS). 34 adults with MS took part. Researchers measured fatigue using questionnaires and physical tasks, then checked blood samples for th…
Matched conditions: MULTIPLE SCLEROSIS
Sponsor: University Medical Center Groningen • Aim: Knowledge-focused
Last updated May 26, 2026 01:25 UTC
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Scientists uncover clues to how MS drug calms the immune system
Knowledge-focused CompletedThis study looked at how the drug cladribine affects the immune system in people with multiple sclerosis (MS). Researchers wanted to better understand its anti-inflammatory and possible nerve-protecting effects. The study included 77 adults with different types of MS, as well as …
Matched conditions: MULTIPLE SCLEROSIS
Phase: NA • Sponsor: University Hospital, Rouen • Aim: Knowledge-focused
Last updated May 26, 2026 01:25 UTC
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MRI showdown: which scan best reveals MS activity?
Knowledge-focused CompletedThis study tested two different MRI techniques to see which one better detects active inflammation in the brains of people with multiple sclerosis (MS). 180 adults with MS or similar conditions had brain scans after a recent flare-up. The goal was to find the most sensitive metho…
Matched conditions: MULTIPLE SCLEROSIS
Phase: NA • Sponsor: Fondation Ophtalmologique Adolphe de Rothschild • Aim: Knowledge-focused
Last updated May 26, 2026 01:24 UTC
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MS Drug's immune impact revealed in small study
Knowledge-focused CompletedThis study looked at how the oral medication cladribine changes different types of immune cells in people with relapsing-remitting multiple sclerosis (RRMS). Ten participants were followed for 96 weeks, with blood and spinal fluid samples taken to measure B cells, T cells, and ot…
Matched conditions: MULTIPLE SCLEROSIS
Sponsor: Queen Mary University of London • Aim: Knowledge-focused
Last updated May 26, 2026 01:24 UTC
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MS drug safety knowledge put to the test in european survey
Knowledge-focused CompletedThis completed study surveyed 335 healthcare professionals and people with multiple sclerosis (or their caregivers) in Europe. The goal was to see if they understood the safety steps needed when using the drug Mayzent (siponimod). Participants answered questions about proper use,…
Matched conditions: MULTIPLE SCLEROSIS
Sponsor: Novartis Pharmaceuticals • Aim: Knowledge-focused
Last updated May 26, 2026 01:23 UTC
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MS study reveals how brain fog changes gait and gaze
Knowledge-focused CompletedThis study looked at how thinking and emotional difficulties impact the way people with multiple sclerosis walk and visually explore their surroundings. Researchers compared 32 MS patients with and without these neuropsychological issues. Participants completed thinking and mood …
Matched conditions: MULTIPLE SCLEROSIS
Phase: NA • Sponsor: Lille Catholic University • Aim: Knowledge-focused
Last updated May 26, 2026 01:23 UTC
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New study reveals how MS drug affects Babies' immune cells in the womb
Knowledge-focused CompletedThis study looked at 70 pregnant women with multiple sclerosis or clinically isolated syndrome who received ocrelizumab before or during early pregnancy. Researchers measured B cell levels in their infants to see how much of the drug passed through the placenta. The goal was to u…
Matched conditions: MULTIPLE SCLEROSIS
Phase: PHASE4 • Sponsor: Hoffmann-La Roche • Aim: Knowledge-focused
Last updated May 26, 2026 01:23 UTC
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MS and muscle loss: surprising link to breathing problems?
Knowledge-focused CompletedThis study looked at how muscle loss (sarcopenia) relates to breathing strength in people with multiple sclerosis. Forty participants completed breathing and grip strength tests in a single session. The goal was to understand if muscle structure affects lung function, which could…
Matched conditions: MULTIPLE SCLEROSIS
Sponsor: Uskudar University • Aim: Knowledge-focused
Last updated May 26, 2026 01:22 UTC
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Head-to-Head: which MS drug works better in the real world?
Knowledge-focused CompletedThis study looked at medical records of over 2,600 people with multiple sclerosis (MS) to compare two drugs: Kesimpta and Ocrevus. The goal was to see which one better prevents relapses and reduces healthcare costs. Researchers used existing data from insurance claims, not a new …
Matched conditions: MULTIPLE SCLEROSIS
Sponsor: Novartis Pharmaceuticals • Aim: Knowledge-focused
Last updated May 26, 2026 01:22 UTC
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New bladder symptom survey tested in turkish MS patients
Knowledge-focused CompletedThis study checked if a Turkish version of a bladder symptom questionnaire works well for people with multiple sclerosis (MS). Researchers asked 71 adults with MS to fill out the survey and compared it to another bladder questionnaire. The goal was to make sure the Turkish versio…
Matched conditions: MULTIPLE SCLEROSIS
Sponsor: Kutahya Health Sciences University • Aim: Knowledge-focused
Last updated May 26, 2026 01:22 UTC
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MS and its medications may impact ovarian health, new study suggests
Knowledge-focused CompletedThis study looked at whether multiple sclerosis (MS) and its treatments affect a woman's egg reserve, measured by a hormone called AMH. Researchers analyzed blood samples from over 800 women with MS or a related condition, aged 18 to 35. The goal was to help doctors decide when t…
Matched conditions: MULTIPLE SCLEROSIS
Sponsor: University Hospital, Clermont-Ferrand • Aim: Knowledge-focused
Last updated May 26, 2026 01:21 UTC
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Patch vs. pill: new ozanimod skin patch tested in healthy volunteers
Knowledge-focused CompletedThis study tested a new skin patch (transdermal delivery system) for the drug ozanimod, which is used to treat multiple sclerosis and ulcerative colitis. Researchers wanted to see how well the drug is absorbed through the skin compared to taking it as an oral capsule. Twenty-four…
Matched conditions: MULTIPLE SCLEROSIS
Sponsor: Corium Innovations, Inc. • Aim: Knowledge-focused
Last updated May 26, 2026 01:21 UTC
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Could a 6-Meter walk test replace the standard for MS patients?
Knowledge-focused CompletedThis study involved 21 adults with multiple sclerosis to check if a 6-minute walk test done in a 6-meter hallway is as good as the usual 30-meter version. Participants walked back and forth for six minutes while their performance was measured. The goal was to see if the shorter v…
Matched conditions: MULTIPLE SCLEROSIS
Sponsor: Haute Ecole de Santé Vaud • Aim: Knowledge-focused
Last updated May 26, 2026 01:19 UTC
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Serotonin receptor may be key to unlocking MS mysteries
Knowledge-focused CompletedThis study looked at whether a serotonin receptor called 5-HT7 could be used as a biomarker for multiple sclerosis (MS). Researchers measured how much of this receptor was on different blood cells from 100 people, including healthy volunteers and MS patients on stable treatment. …
Matched conditions: MULTIPLE SCLEROSIS
Sponsor: Centre Hospitalier Régional d'Orléans • Aim: Knowledge-focused
Last updated May 26, 2026 01:19 UTC
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Eye-Tracking tech could unlock MS secrets
Knowledge-focused CompletedThis study looked at whether tracking eye movements can help measure disease severity and thinking abilities in people with multiple sclerosis (MS). Researchers used special eye-tracking technology on 120 adults with MS to gather data. The goal was to train computer algorithms to…
Matched conditions: MULTIPLE SCLEROSIS
Sponsor: Innodem Neurosciences • Aim: Knowledge-focused
Last updated May 26, 2026 01:19 UTC
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Custom gait training beats one-size-fits-all for spinal patients
Knowledge-focused CompletedThis study tested whether tailoring walking exercises to each person's specific walking problems (identified by 3D motion analysis) works better than standard walking therapy. 63 adults with spinal cord injury or multiple sclerosis who had mild to moderate walking difficulties to…
Matched conditions: MULTIPLE SCLEROSIS
Phase: NA • Sponsor: University of Zurich • Aim: Knowledge-focused
Last updated May 26, 2026 01:19 UTC
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Sleep quality linked to fatigue and function in MS patients
Knowledge-focused CompletedThis study looked at 102 adults with multiple sclerosis to see how good or poor sleep relates to body awareness, tiredness, and ability to use arms and legs. Researchers compared those with good sleep to those with poor sleep using questionnaires and physical tests. The goal was …
Matched conditions: MULTIPLE SCLEROSIS
Sponsor: Gulhane School of Medicine • Aim: Knowledge-focused
Last updated May 26, 2026 01:19 UTC
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Spinal fluid clues may reveal who will develop MS
Knowledge-focused CompletedThis study looked at 100 people who have brain scan abnormalities but no MS symptoms (radiologically isolated syndrome). Researchers measured four substances in their spinal fluid and blood to see if any could predict who later develops multiple sclerosis. The goal was to find be…
Matched conditions: MULTIPLE SCLEROSIS
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 26, 2026 01:17 UTC
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Can your eyes reveal MS severity? new study says yes
Knowledge-focused CompletedThis study looked at whether tracking eye movements can help measure how severe multiple sclerosis (MS) is and how it affects thinking skills. Researchers used a special eye-tracking app on 200 people with MS to collect data. The goal was to train computer programs to spot reliab…
Matched conditions: MULTIPLE SCLEROSIS
Sponsor: Innodem Neurosciences • Aim: Knowledge-focused
Last updated May 26, 2026 01:17 UTC
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New risk score aims to predict multiple sclerosis before symptoms start
Knowledge-focused CompletedThis study looked at whether a score that combines genetic and environmental factors can help predict who might develop multiple sclerosis (MS). Researchers studied 181 people, including those with MS and their close relatives. Participants provided medical history, blood, and sa…
Matched conditions: MULTIPLE SCLEROSIS
Sponsor: National Institute of Neurological Disorders and Stroke (NINDS) • Aim: Knowledge-focused
Last updated May 26, 2026 01:16 UTC
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MS and depression: can you read emotions?
Knowledge-focused CompletedThis study looked at how depression impacts the ability to recognize emotions on people's faces in those with multiple sclerosis (MS). Researchers compared 38 participants, including people with MS and healthy controls, using tests that involved identifying angry, happy, or neutr…
Matched conditions: MULTIPLE SCLEROSIS
Sponsor: Lille Catholic University • Aim: Knowledge-focused
Last updated May 26, 2026 01:16 UTC
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Gene hunt aims to prevent liver damage in MS patients
Knowledge-focused CompletedThis study looked at 300 people with multiple sclerosis (MS) to see if certain genes are linked to liver injury caused by beta-interferon, a common MS treatment. Researchers compared patients who had liver damage to those who did not. The goal was to find genetic markers that cou…
Matched conditions: MULTIPLE SCLEROSIS
Sponsor: University of British Columbia • Aim: Knowledge-focused
Last updated May 26, 2026 01:15 UTC
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MS Patients' social struggles traced in brain scans
Knowledge-focused CompletedThis study used brain scans to understand why people with multiple sclerosis (MS) sometimes have trouble with social thinking, like understanding others' feelings. Researchers compared 35 adults with relapsing-remitting MS to healthy volunteers. No treatment was given; the goal w…
Matched conditions: MULTIPLE SCLEROSIS
Phase: NA • Sponsor: University Hospital, Bordeaux • Aim: Knowledge-focused
Last updated May 26, 2026 01:15 UTC
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Iron nanoparticle could reveal hidden brain inflammation in MS
Knowledge-focused CompletedThis study looked at whether ferumoxytol, an iron-based contrast agent, can help spot inflammation in the brains of people with multiple sclerosis (MS) using a powerful 7 Tesla MRI. Fourteen participants (some with MS, some healthy) received ferumoxytol and had multiple MRI scans…
Matched conditions: MULTIPLE SCLEROSIS
Phase: PHASE1 • Sponsor: National Institute of Neurological Disorders and Stroke (NINDS) • Aim: Knowledge-focused
Last updated May 26, 2026 01:14 UTC
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MS Patients' ability to spot joy and kindness put to the test
Knowledge-focused CompletedThis study looked at whether people with multiple sclerosis (MS) can recognize positive emotions as well as healthy people. Researchers showed 101 participants (some with MS, some without) faces and voices expressing different emotions and asked them to identify the emotion and r…
Matched conditions: MULTIPLE SCLEROSIS
Phase: NA • Sponsor: Lille Catholic University • Aim: Knowledge-focused
Last updated May 22, 2026 14:05 UTC
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Spinal fluid clues may unlock multiple sclerosis mysteries
Knowledge-focused CompletedThis study looked at whether proteins in spinal fluid can help doctors diagnose multiple sclerosis (MS) and predict how the disease will progress. Researchers analyzed fluid from 161 people with MS and other nervous system conditions. The goal is to create better tools for person…
Matched conditions: MULTIPLE SCLEROSIS
Sponsor: Washington University School of Medicine • Aim: Knowledge-focused
Last updated May 22, 2026 14:03 UTC
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Scientists investigate immune cell clues in multiple sclerosis
Knowledge-focused CompletedThis study explored whether a certain type of immune cell, called 4BL, is involved in multiple sclerosis (MS). Researchers compared blood samples from 125 people, including those with newly diagnosed MS, people with other neurological diseases, and healthy volunteers. The goal wa…
Matched conditions: MULTIPLE SCLEROSIS
Sponsor: University Hospital, Lille • Aim: Knowledge-focused
Last updated May 22, 2026 14:03 UTC
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Lockdown's hidden toll: MS relapses went under the radar during pandemic
Knowledge-focused CompletedThis study looked at how the first wave of COVID-19 (April–June 2020) changed the way people with multiple sclerosis reported relapses and how doctors managed them, compared to the same months in 2019. Researchers reviewed records from 51 patients across 5 UK hospitals to see if …
Matched conditions: MULTIPLE SCLEROSIS
Sponsor: Nottingham University Hospitals NHS Trust • Aim: Knowledge-focused
Last updated May 22, 2026 14:01 UTC
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Blood tests may reveal if unusual MS is a different disease
Knowledge-focused CompletedThis study looked at 58 people to see if those with an unusual form of multiple sclerosis (MS) have different levels of nerve damage markers in their blood compared to people with classic MS and healthy controls. The goal was to better understand if these atypical cases are a sep…
Matched conditions: MULTIPLE SCLEROSIS
Phase: NA • Sponsor: University Hospital, Montpellier • Aim: Knowledge-focused
Last updated May 22, 2026 14:01 UTC
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MS treatment study investigates disparities in access and outcomes
Knowledge-focused CompletedThis study reviewed medical records of 800 multiple sclerosis patients to see if gender, race, or socioeconomic background influenced how quickly they started Ocrelizumab or how well it worked. Researchers looked at relapse rates and MRI changes over 12-24 months. The goal is to …
Matched conditions: MULTIPLE SCLEROSIS
Sponsor: Brigham and Women's Hospital • Aim: Knowledge-focused
Last updated May 22, 2026 13:55 UTC
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Severe MS Patients' breathing troubles revealed in new study
Knowledge-focused CompletedThis study aimed to describe breathing problems in 70 people with severe multiple sclerosis (MS). Researchers measured how well the breathing muscles work and tested lung function. The goal was to better understand respiratory issues in this group, not to test a new treatment.
Matched conditions: MULTIPLE SCLEROSIS
Phase: NA • Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated May 22, 2026 13:52 UTC
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New study reveals how mindfulness and 'Flow' could boost mental health after MS diagnosis
Knowledge-focused CompletedThis study looked at 361 people who were diagnosed with multiple sclerosis (MS) within the past year. Researchers wanted to see if being mindful and having 'flow' experiences (being fully absorbed in an activity) are linked to better mental health. Participants filled out questio…
Matched conditions: MULTIPLE SCLEROSIS
Sponsor: Marta Bassi • Aim: Knowledge-focused
Last updated May 22, 2026 13:50 UTC
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New walking test could better measure daily challenges in MS
Knowledge-focused CompletedThis study tested whether a walking test called the L Test is a reliable way to measure movement and thinking at the same time in people with multiple sclerosis (MS). 50 adults with mild to moderate MS completed the test, which involves walking in an L-shape while also doing a me…
Matched conditions: MULTIPLE SCLEROSIS
Sponsor: Sanko University • Aim: Knowledge-focused
Last updated May 20, 2026 11:56 UTC
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MS and menstrual cycle: exercise study reveals new insights
Knowledge-focused CompletedThis study looked at how women with multiple sclerosis (MS) feel about and respond to exercise during different phases of their menstrual cycle. Fifteen women with MS and fifteen without did high-intensity interval training and strength training sessions. Researchers measured sat…
Matched conditions: MULTIPLE SCLEROSIS
Phase: NA • Sponsor: Universidad de Almeria • Aim: Knowledge-focused
Last updated May 20, 2026 11:55 UTC
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New study digs into MS fatigue: how do we really measure it?
Knowledge-focused CompletedThis study looked at fatigue in 60 people with relapsing-remitting multiple sclerosis (MS). Researchers compared how fatigue is measured using patient questionnaires (subjective), physical tests like walking and grip strength (objective), and cognitive tests. The goal was to see …
Matched conditions: MULTIPLE SCLEROSIS
Sponsor: Asli Demirtaş • Aim: Knowledge-focused
Last updated May 19, 2026 12:01 UTC
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Libya study reveals gaps in MS diagnosis and treatment access
Knowledge-focused CompletedThis study looked at how quickly people with multiple sclerosis (MS) in Libya get diagnosed and treated, and how that affects their disability. Researchers reviewed data from 369 adults with MS at two hospitals. The goal is to find gaps in care and improve services for patients i…
Matched conditions: MULTIPLE SCLEROSIS
Sponsor: University of Zintan • Aim: Knowledge-focused
Last updated May 19, 2026 11:59 UTC
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New models could help robots assist arm rehabilitation
Knowledge-focused CompletedThis study involved 32 people with arm weakness caused by stroke, multiple sclerosis, or spinal cord injury. Researchers measured how much force participants could voluntarily produce in their arm muscles at different angles and speeds. They used this data to build mathematical m…
Matched conditions: MULTIPLE SCLEROSIS
Phase: NA • Sponsor: Pôle Saint Hélier • Aim: Knowledge-focused
Last updated May 19, 2026 11:48 UTC
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New computer test spots early brain fog in MS patients
Knowledge-focused CompletedThis study tested a short, computer-based thinking and memory test for people with multiple sclerosis (MS). The goal was to see if it could quickly spot early cognitive problems, like slow information processing and memory issues. Over 400 French-speaking adults with MS took the …
Matched conditions: MULTIPLE SCLEROSIS
Phase: NA • Sponsor: University Hospital, Bordeaux • Aim: Knowledge-focused
Last updated May 18, 2026 12:13 UTC
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Brain scans reveal clues to MS fatigue mystery
Knowledge-focused CompletedThis study looked at 10 people with multiple sclerosis to understand why they feel tired. Researchers used special brain scans to measure inflammation and chemical activity. They did not test any new treatments. The goal was to learn more about what causes MS-related fatigue.
Matched conditions: MULTIPLE SCLEROSIS
Phase: PHASE1, PHASE2 • Sponsor: Brigham and Women's Hospital • Aim: Knowledge-focused
Last updated May 18, 2026 12:09 UTC
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Tiny sensors could reveal hidden walking troubles in early MS
Knowledge-focused CompletedThis study tested whether small wearable motion sensors can detect early walking and balance issues in people with multiple sclerosis (MS). Researchers compared 70 participants (MS patients and healthy volunteers) as they walked and performed balance tasks. The goal was to see if…
Matched conditions: MULTIPLE SCLEROSIS
Sponsor: Lille Catholic University • Aim: Knowledge-focused
Last updated May 18, 2026 12:07 UTC
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Gene mutation may influence MS drug safety in chinese patients
Knowledge-focused CompletedThis study looked at 82 Chinese adults with multiple sclerosis to see if a specific gene change (ABCG2 mutation) affects how the body processes the drug teriflunomide. Participants took the drug daily for 24 weeks, and researchers measured drug levels and tracked side effects lik…
Matched conditions: MULTIPLE SCLEROSIS
Phase: PHASE4 • Sponsor: Sanofi • Aim: Knowledge-focused
Last updated May 18, 2026 12:02 UTC
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New study reveals how MS drug passes through breastmilk to babies
Knowledge-focused CompletedThis study looked at how much of the multiple sclerosis (MS) drug ocrelizumab gets into breastmilk and whether it affects babies' immune cells. Twenty-six breastfeeding women with MS or a first MS-like episode took part. Researchers measured drug levels in breastmilk and checked …
Matched conditions: MULTIPLE SCLEROSIS
Phase: PHASE4 • Sponsor: Hoffmann-La Roche • Aim: Knowledge-focused
Last updated May 18, 2026 11:59 UTC
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Personalized diet advice tested for MS patients
Knowledge-focused CompletedThis study looked at whether personalized dietary advice from a dietitian helps people with multiple sclerosis (MS) increase their calcium intake compared to just receiving a standard information sheet. A total of 182 MS patients who could walk and had never had a diet consultati…
Matched conditions: MULTIPLE SCLEROSIS
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 15, 2026 11:54 UTC
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New test tracks immune response to MS drug in small study
Knowledge-focused CompletedThis study involved 15 people with multiple sclerosis who were already taking the drug alemtuzumab. Researchers wanted to see if the body makes antibodies against the drug and how those antibodies change over 24 months. The goal was to learn more about how these antibodies might …
Matched conditions: MULTIPLE SCLEROSIS
Sponsor: Queen Mary University of London • Aim: Knowledge-focused
Last updated May 14, 2026 12:05 UTC
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Eye camera reveals hidden clues to multiple sclerosis progression
Knowledge-focused CompletedThis study tested a special eye-imaging technique called adaptive optics to look at blood vessel changes in the retina of people with multiple sclerosis (MS). Researchers measured swelling around retinal vessels in 50 participants with different MS types and compared them to heal…
Matched conditions: MULTIPLE SCLEROSIS
Phase: NA • Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated May 13, 2026 16:01 UTC
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Pregnancy and MS: new study tracks moms and babies for three years
Knowledge-focused CompletedThis study followed 168 women with Multiple Sclerosis who were pregnant or planning pregnancy. Researchers conducted phone interviews every three months during pregnancy and tracked babies' growth for up to three years after birth. The goal was to understand how MS and its treatm…
Matched conditions: MULTIPLE SCLEROSIS
Sponsor: Brigham and Women's Hospital • Aim: Knowledge-focused
Last updated May 13, 2026 15:58 UTC
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Scientists engineer 'smarter' IL-2 to tame overactive immune systems
Knowledge-focused CompletedThis study tested specially engineered versions of a natural immune protein (IL-2) in blood samples from 67 people with autoimmune or inflammatory diseases like lupus, multiple sclerosis, and rheumatoid arthritis. The goal was to see if these modified proteins could selectively a…
Matched conditions: MULTIPLE SCLEROSIS
Phase: NA • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Apr 24, 2026 16:18 UTC