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New Gadolinium-Free MRI dye shows promise for brain lesion detection

NCT ID NCT06322342

First seen Jan 11, 2026 · Last updated May 24, 2026 · Updated 16 times

Summary

This study tested a new MRI contrast agent called RVP-001 in 18 adults with brain lesions from conditions like tumors or multiple sclerosis. The goal was to see if it is safe and effective at highlighting these lesions without using gadolinium, a metal that can build up in the body. Participants received a single dose of RVP-001 and had their scans compared to standard gadolinium-enhanced MRIs.

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Contacts and locations

Locations

  • Brigham & Women's Hospital

    Boston, Massachusetts, 02115, United States

  • Duke University Medical Center

    Durham, North Carolina, 27710, United States

  • Massachusetts General Hospital

    Boston, Massachusetts, 02114, United States

  • University of Missouri

    Columbia, Missouri, 65212, United States

  • Yale New Haven Hospital

    New Haven, Connecticut, 06510, United States

Conditions

Explore the condition pages connected to this study.