Brain tumor, recurrent
Clinical trials for Brain tumor, recurrent explained in plain language.
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Sound waves open brain barrier to deliver cancer drug in kids
Disease control Recruiting nowThis early-stage trial tests whether using focused ultrasound with microbubbles can temporarily open the blood-brain barrier, allowing the immunotherapy drug nivolumab to reach brain tumors more effectively. It includes 30 children and young adults with relapsed diffuse midline g…
Matched conditions: BRAIN TUMOR, RECURRENT
Phase 1 • Sponsor: Children's National Research Institute • Aim: Disease control
Last updated Sep 11, 2026 00:00 UTC
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Immune cells engineered to fight brain cancer in kids
Disease control Recruiting nowThis early-phase study tests the safety of a new cell therapy called B7-H3 CAR T cells for children and young adults whose brain tumors have come back or are growing despite standard treatment. The therapy uses the patient's own immune cells, modified to target a protein (B7-H3) …
Matched conditions: BRAIN TUMOR, RECURRENT
Phase 1 • Sponsor: Robbie Majzner • Aim: Disease control
Last updated Sep 05, 2026 00:00 UTC
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New Tile-Shaped radiation device tested for brain tumors
Disease control Recruiting nowThis study is tracking 600 people with brain tumors who receive GammaTile therapy during surgery. GammaTile is a device that delivers radiation directly to the tumor site to help prevent regrowth. Researchers are measuring how long tumors stay under control and how patients feel …
Matched conditions: BRAIN TUMOR, RECURRENT
Sponsor: GT Medical Technologies, Inc. • Aim: Disease control
Last updated Jul 24, 2026 00:00 UTC
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Brain tumor drug delivered via pump shows promise in early trial
Disease control Recruiting nowThis early-phase study tests the safety of delivering the chemotherapy drug topotecan directly to the brain using a pump and catheter system (convection-enhanced delivery) in 6 people with a recurrent, aggressive type of brain tumor called IDH-mutant malignant glioma. The treatme…
Matched conditions: BRAIN TUMOR, RECURRENT
Phase 1 • Sponsor: Jeffrey N. Bruce • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC
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Cannabis spray could boost chemo for deadly brain tumors
Disease control Recruiting nowThis phase II trial tests whether adding a cannabis-based mouth spray (nabiximols) to standard chemotherapy helps people with recurrent glioblastoma live longer. About 120 adults whose brain tumor has returned after initial treatment will receive either the cannabis spray or a pl…
Matched conditions: BRAIN TUMOR, RECURRENT
Phase 2 • Sponsor: University of Birmingham • Aim: Disease control
Last updated Jun 27, 2026 12:29 UTC
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New combo attack on recurrent brain tumors shows promise in early trial
Disease control Recruiting nowThis phase 2 trial tests a new way to deliver the cancer drug cetuximab directly into the brain's arteries, along with mannitol to open the blood-brain barrier, plus targeted radiation. It is for adults with recurrent glioblastoma or other aggressive brain tumors that have high l…
Matched conditions: BRAIN TUMOR, RECURRENT
Phase 2 • Sponsor: Northwell Health • Aim: Disease control
Last updated Jun 27, 2026 12:06 UTC
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Sound waves could boost brain cancer drug delivery
Disease control Recruiting nowThis Phase 3 trial tests whether combining the drug Avastin with a focused ultrasound system (NaviFUS) can improve outcomes for people with recurrent glioblastoma, an aggressive brain cancer. The ultrasound temporarily opens the blood-brain barrier to let more drug reach the tumo…
Matched conditions: BRAIN TUMOR, RECURRENT
Phase 3 • Sponsor: NaviFUS Corporation • Aim: Disease control
Last updated Jun 27, 2026 12:05 UTC