Brain tumor, recurrent
Clinical trials for Brain tumor, recurrent explained in plain language.
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Supercharged immune cells injected into brain to fight tumors
Disease control OngoingThis early-phase trial tests a new approach for people with HER2-positive brain tumors that have come back or not responded to standard treatment. Researchers take the patient's own T cells, attach a special antibody (anti-HER2) to them, and inject these 'CAR T cells' directly in…
Matched conditions: BRAIN TUMOR, RECURRENT
Phase 1 • Sponsor: Baylor College of Medicine • Aim: Disease control
Last updated Sep 17, 2026 00:00 UTC
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Can a common antidepressant boost brain tumor treatment?
Knowledge-focused OngoingThis early-phase trial tests whether fluoxetine, an FDA-approved antidepressant, can increase stress in cell structures called lysosomes to make the chemotherapy drug temozolomide more effective against recurrent brain tumors. Ten participants with recurrent glioma will receive e…
Matched conditions: BRAIN TUMOR, RECURRENT
Early phase 1 • Sponsor: Duke University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:51 UTC