BRAIN TUMOR, RECURRENT
Clinical trials for BRAIN TUMOR, RECURRENT explained in plain language.
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Brain cancer drug delivered directly into tumor shows promise in early trial
Disease control CompletedThis early-phase study tested a new drug called D2C7-IT in 81 adults with recurrent malignant glioma, a serious brain cancer. The drug was infused directly into the tumor over 72 hours using a special delivery method. The main goal was to find the safest dose and check for side e…
Matched conditions: BRAIN TUMOR, RECURRENT
Phase: PHASE1 • Sponsor: Darell Bigner • Aim: Disease control
Last updated May 26, 2026 04:36 UTC
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Sound waves and radiation team up against returning brain tumors
Disease control CompletedThis small pilot study tested whether combining focused ultrasound with a second round of radiation is safe and helpful for people with recurrent glioblastoma, an aggressive brain cancer. Seven adults who had already tried standard treatments received the combination therapy as o…
Matched conditions: BRAIN TUMOR, RECURRENT
Phase: NA • Sponsor: NaviFUS Corporation • Aim: Disease control
Last updated May 19, 2026 11:48 UTC
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New MRI dye shows promise for spotting brain tumors
Diagnosis CompletedThis study tested a new contrast agent called Elucirem (gadopiclenol) for MRI scans of brain gliomas. It involved 138 adults with new or returning brain tumors. The goal was to see if Elucirem produced clearer images than the standard contrast agent, Dotarem, when measuring blood…
Matched conditions: BRAIN TUMOR, RECURRENT
Phase: PHASE3 • Sponsor: Guerbet • Aim: Diagnosis
Last updated May 26, 2026 05:01 UTC
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New Gadolinium-Free MRI dye shows promise for brain lesion detection
Diagnosis CompletedThis study tested a new MRI contrast agent called RVP-001 in 18 adults with brain lesions from conditions like tumors or multiple sclerosis. The goal was to see if it is safe and effective at highlighting these lesions without using gadolinium, a metal that can build up in the bo…
Matched conditions: BRAIN TUMOR, RECURRENT
Phase: PHASE2 • Sponsor: Reveal Pharmaceuticals Inc. • Aim: Diagnosis
Last updated May 26, 2026 04:35 UTC
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Glow-in-the-Dark dye helps surgeons spot hidden brain tumors
Knowledge-focused CompletedThis study tested a technique called TumorGlow, where a dye is injected into patients before brain tumor surgery. The dye makes tumor cells glow under a special camera, helping surgeons see and remove more of the tumor. The goal was to improve how completely tumors are removed, w…
Matched conditions: BRAIN TUMOR, RECURRENT
Phase: PHASE1 • Sponsor: University of Pennsylvania • Aim: Knowledge-focused
Last updated May 26, 2026 05:07 UTC