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Scientists investigate immune cells in multiple sclerosis

NCT ID NCT03796611

Knowledge-focused Sponsor: University Hospital, Lille Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study examined a type of immune cell called 4BL B cells in people with multiple sclerosis (MS) and compared them to healthy controls. Researchers wanted to see if these cells are more common in MS and might contribute to inflammation. The study involved 125 participants and was completed by the University Hospital, Lille.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If this study finds a link between 4BL cells and MS inflammation, it could point toward new targets for future treatments.
What could go wrong
This is an observational study, not a treatment trial. It only looks at cells in the lab, so any potential treatment is far off and uncertain.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

125 people

The number who actually took part.

Started

Jul 2017

Finished

Aug 2017

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

MS patients and controls: healthy controls and patients having non-MS neurological inflammatory disease and patients having other non inflammatory neurological disease.

Ages

18 to 60 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria for MS group: * MS defined by McDonald 2017 criteria with a disease duration of less than 1 year * between 18 and 60 years old patients * naïve of any immune therapy or steroid intake * patients who signed consent to the study Inclusion Criteria for controls with inflammatory of non inflammatory neurological disease: * patients who signed consent to the study * between 18 and 60 years old patients * naïve of any steroid intake or immune therapy Inclusion criteria for healthy controls: * control who signed consent at transfusion center for their blood collect to be used for study * between 18 and 60 years old patients * naïve of any steroid intake or immune therapy Exclusion Criteria: * pregnancy or breast-feeding * patients or controls unable to sign the consent or to consent

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Conditions

The condition(s) this trial relates to.

multiple sclerosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Multiple sclerosis

Contacts and locations

Locations

  • chu de Lille

    Lille, France

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Other studies related to the condition(s) this trial covers.