Wheelchair workout shows promise for MS symptom relief
NCT ID NCT05888727
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested a 16-week home exercise program called SPIN for people with multiple sclerosis who use a wheelchair. Twenty-four participants were randomly assigned to either the exercise program or a wellness program. Researchers checked if the program was safe, doable, and liked by participants, and also looked for improvements in symptoms and metabolic health.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- wheelchair exercise-training program (SPIN)
- What this could lead to
- If it works, this could offer a safe, home-based exercise option to help manage MS symptoms and improve health in wheelchair users.
- What could go wrong
- This is a small, early feasibility study with only 24 participants, so results may not apply to everyone. The program requires motivation and may not benefit all users.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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24 people
The number who actually took part.
- Started
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Jan 2024
- Finished
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May 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * diagnosis of MS * self-reported use of a wheelchair (i.e., manual wheelchair, power wheelchair, or scooter) \>50% of the time * age of 18 years or older * relapse free for the past 30 days * being non-active defined as not engaging in regular physical activity (30 minutes accumulated per day) on more than 2 days of the week during the previous 6 months (i.e., not meeting current physical activity guidelines for MS) Exclusion Criteria: * during telephone screening participants will complete an exercise pre-participation health screen and if participants report any symptoms or conditions contradictive of exercise then physician clearance will be required before enrollment
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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The University of Texas Health Science Center at Houston
Houston, Texas, 77030, United States
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Other studies related to the condition(s) this trial covers.
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