MULTIPLE SCLEROSIS

This study tested whether clemastine fumarate, an allergy medicine, could improve eye movement in people with multiple sclerosis (MS) who have a specific eye condition called internuclear ophthalmoparesis. The trial planned to enroll 80 participants but was terminated early. Rese…

This study tested an oral drug called SAR443820 in 174 adults aged 18 to 60 with multiple sclerosis (MS). The goal was to see if the drug could lower a marker of nerve damage in the blood. The study was stopped early because the drug did not work better than a placebo. No major s…

This study aimed to see if the drug alemtuzumab could help children aged 10 to 17 with relapsing-remitting multiple sclerosis (MS) whose disease was still active despite other treatments. Researchers planned to measure brain lesions and safety. The trial was terminated early, so …

This study tested a new device (DDS) to see if it could accurately detect swallowing problems in people with conditions like stroke, Parkinson's disease, multiple sclerosis, Alzheimer's, or dementia. The device was compared to a standard X-ray test. The study was stopped early be…

This early-phase study aimed to check if a single dose of bryostatin is safe for people with multiple sclerosis who are already on standard treatments. Only 4 participants were enrolled before the study was stopped. Researchers tracked side effects and brain inflammation using MR…

This study tested a hand rehabilitation program for people with multiple sclerosis who have trouble with hand sensitivity. The program used a device called TENS to stimulate nerves and improve feeling in the hands. The goal was to improve quality of life and hand function. The st…

This study aimed to see if the drug ozanimod could reduce fatigue in people with multiple sclerosis (MS). Researchers planned to follow 26 adults with MS for three months, measuring fatigue with questionnaires and looking at brain MRI scans. The study was terminated early, so res…

This study tested a wearable device called Syde® to see if it can accurately track daily activity in people with multiple sclerosis (MS). Researchers compared the device's data to standard clinic tests like walking speed and disability scores. The goal was to find a simpler way t…

This study looked at whether certain markers on immune cells in the blood can predict if multiple sclerosis (MS) will become active again after stopping the drug ozanimod. Researchers planned to follow 23 adults with MS, measuring these markers before and after starting or stoppi…

This study looked at whether special MRI scans can detect early changes in the brain caused by Tysabri, a treatment for multiple sclerosis. Researchers planned to follow 70 people with relapsing-remitting MS for two years. The goal was to find MRI patterns that predict how well s…