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MS and emotions: study investigates whether positive feelings are still recognized

NCT ID NCT04804787

Knowledge-focused Sponsor: Lille Catholic University Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compared 101 people with multiple sclerosis to healthy volunteers to see if they can recognize positive emotions like joy and enthusiasm. Participants completed questionnaires and tests to evaluate their ability to identify emotions from faces and voices. The goal was to understand whether emotion recognition is preserved in MS, which could help guide future support strategies.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

101 people

The number who actually took part.

Started

Jun 2021

Finished

Feb 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 55 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Male or female between 18 and 55 years old. * Understand and able to express themselves in French. * EXPERIMENTAL GROUP : * Relapsing-remitting form (RRMS) * With an EDSS \< 4 (Expanded Disability Status Scale) * No significant motor, cerebellar or somatosensory disorders of the upper limbs or visual disorders (EDSS specific parameter \<2) * No flare-up in the last 6 weeks * No corticosteroids taken in the last 4 weeks * CONTROL GROUP : * Lack of global cognitive deterioration (according to Brief International Cognitive Assessment for Multiple Sclerosis (BICAMS) standards). * Gender, age and education level matching to the multiple sclerosis patients * Understanding and signing the informed consent and information letter regarding participation in the study. * Benefiting from health insurance coverage. Exclusion Criteria: * Persons with previous neurological pathologies, head trauma with loss of consciousness, psychiatric pathologies, serious general affections, perceptive or dysarthric disorders preventing verbal communication or reading, * People with sensory disorders (visual and auditory) that interfere with the performance of neuropsychological tests; * Treatment with psychotropic drugs (except benzodiazepines and hypnotics). * Refusal to participate after clear and fair information about the study. * Major persons under guardianship, under judicial protection, persons deprived of liberty. * Pregnant or breastfeeding women

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Conditions

The condition(s) this trial relates to.

Cognitive Dysfunction multiple sclerosis relapsing-remitting multiple sclerosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Multiple sclerosis

Contacts and locations

Locations

  • Hôpital Saint-Vincent de Paul

    Lille, 59000, France

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