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Virtual reality hand training shows promise for MS arm weakness

NCT ID NCT06107023

Symptom relief Sponsor: Abant Izzet Baysal University Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether watching 3D virtual reality videos of hand and arm movements could improve upper limb function in people with multiple sclerosis (MS). Thirty-two participants with recent MS and moderate disability completed six weeks of training. Researchers measured hand speed, grip strength, fatigue, thinking skills, daily activities, and quality of life. The goal was to see if this simple, drug-free approach could help manage MS symptoms.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
action observation training with 3D virtual reality
What this could lead to
If it works, this could offer a simple, drug-free way to improve arm function and quality of life for people with multiple sclerosis.
What could go wrong
This is a small, early-stage study with only 32 participants, so results may not apply to everyone. The training is behavioral, so benefits may be modest and not long-lasting.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

32 people

The number who actually took part.

Started

Nov 2023

Finished

Mar 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * \< 2 years MS diagnosis according to McDonald criteria * between 3.5 and 6 the EDSS * Nine Hole Peg Test \> 30s for at least one upper extremity * no change in medication in the last 6 months * having MS disease with ongoing attacks * \>2 Modified Ashworth Scale in the upper extremities * MOCA\>25 Exclusion Criteria: * diagnosed with neurological (except MS), cardiopulmonary, metabolic or musculoskeletal disease that would prevent treatment and evaluation * receiving botulinum toxin treatment in the last 6 months * visual impairment uncorrected by optical devices * inability to adapt to treatment based on 3D immersive virtual reality (e.g. with cognitive impairment, communication problems, psychological problems or vestibular system problems)

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Conditions

The condition(s) this trial relates to.

multiple sclerosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Multiple sclerosis

Contacts and locations

Locations

  • Izzet Baysal University

    Bolu, Center, 14030, Turkey (Türkiye)

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