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Gene mutation may influence MS drug safety in chinese patients

NCT ID NCT04410965

First seen Oct 31, 2025 · Last updated May 17, 2026 · Updated 27 times

Summary

This study looked at 82 Chinese adults with multiple sclerosis to see if a specific gene change (ABCG2 mutation) affects how the body processes the drug teriflunomide. Participants took the drug daily for 24 weeks, and researchers measured drug levels and tracked side effects like hair thinning, diarrhea, and liver changes. The goal was to better understand safety and drug exposure in this population.

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Contacts and locations

Locations

  • Investigational Site Number

    China, China

Conditions

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