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Zapping the brain with electricity may help MS patients think clearer

NCT ID NCT07160218

Symptom relief Sponsor: Shahid Beheshti University of Medical Sciences Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tested whether a combination of mild brain stimulation (tDCS) and computer-based cognitive training could improve memory, attention, and brain flexibility in people with multiple sclerosis. Forty-five adults with relapsing-remitting MS took part. The goal was to see if these non-invasive treatments could help with common thinking problems that affect daily life.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
transcranial direct current stimulation (tDCS) and computer-based cognitive rehabilitation exercises
What this could lead to
If it works, this approach could offer a non-drug way to ease cognitive problems like memory and attention in people with multiple sclerosis.
What could go wrong
This is a small, early-stage trial with only 45 participants. The results may not apply to everyone with MS, and the benefits might be modest or temporary.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

45 people

The number who actually took part.

Started

Jan 2024

Finished

Aug 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

20 to 50 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: Age between 20 and 50 years. Diagnosed with relapsing-remitting multiple sclerosis (RRMS). Mild disability, defined as EDSS \< 5. Patients who attended the neurology clinic and are willing to participate. Exclusion Criteria: Presence of psychiatric disorders requiring treatment with neuroleptics. History of seizures. Left-handed individuals. Recent MS relapse requiring steroid treatment. Pregnant women. History of brain surgery or presence of intracranial clips.

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Conditions

The condition(s) this trial relates to.

multiple sclerosis relapsing-remitting multiple sclerosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Multiple sclerosis

Contacts and locations

Locations

  • Shahid Beheshti University of Medical Science

    Tehran, Iran

More trials for these conditions

Other studies related to the condition(s) this trial covers.