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MIND diet tested for MS: a Brain-Healthy eating plan to fight fatigue and fog

NCT ID NCT07057999

Symptom relief Sponsor: Betul Uner Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This completed study tested whether the MIND diet—a mix of Mediterranean and DASH diets—could improve fatigue, quality of life, and brain fog in 62 adults with multiple sclerosis. Participants followed either the MIND diet or a traditional healthy diet for 3 months, with weekly online check-ins. Researchers measured changes using questionnaires and blood tests to see if this eating plan offers extra benefits for MS symptoms.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
MIND diet (a combination of Mediterranean and DASH diets)
What this could lead to
If it works, this could offer a simple dietary approach to help manage fatigue and brain fog in people with multiple sclerosis.
What could go wrong
This is a small, completed trial with 62 participants, so results may not apply to everyone. Dietary changes can be hard to maintain, and any benefits might be modest.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

62 people

The number who actually took part.

Started

Jun 2025

Finished

Dec 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adult MS patients between the ages of 18-65 diagnosed according to the 2017 McDonald criteria * Having been diagnosed with MS at least three months ago; patients are called for routine check-ups in the first and third months after starting treatment, as liver function tests and/or hemogram values may be impaired due to the treatment they started when they are newly diagnosed with MS. For this reason, it was planned to include patients whose check-ups were completed and no unexpected changes were observed in the blood parameters table due to the medication. * No DMT change in the last 6 months * Patients who use their medications regularly * Not using nutritional support or supplements * Patients with an EDSS score of ≤6 * Patients with a body mass index (BMI) between 18.5-24.9 kg/m2 Exclusion Criteria: * MS patients who are pregnant or lactating * Having another chronic metabolic disease and/or having had surgery in the last 3 months * MS patients with limb deficiency * MS patients on a special diet * Patients using antidepressants and/or mood stabilizers * Having had an attack and/or receiving steroid treatment in the last month

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Conditions

The condition(s) this trial relates to.

Mental Fatigue multiple sclerosis myalgic encephalomeyelitis/chronic fatigue syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Body composition Brain fog Diet therapy Fatigue syndrome, chronic Multiple sclerosis Quality of life (QOL) Randomised controlled trial

Contacts and locations

Locations

  • Muğla Sıtkı Koçman University/Muğla Training and Research Hospital Neurology Polyclinic

    Muğla, Mentese, 48000, Turkey (Türkiye)

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