Centre Hospitalier Universitaire, Amiens
Clinical trials sponsored by Centre Hospitalier Universitaire, Amiens, explained in plain language.
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New hip cup shows promise in preventing dislocation after revision surgery
Disease control CompletedThis study looked at 62 patients who had hip replacement revision surgery. Doctors used a special type of cup (dual-mobility cup) cemented into a metal reinforcement to see if it could prevent the hip from dislocating or loosening over time. Patients were followed for at least 5 …
Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Disease control
Last updated Jun 16, 2026 18:48 UTC
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Nurse coaching boosts RA Patients' ability to handle biologic drugs
Disease control CompletedThis study tested whether a special nurse consultation could help people with rheumatoid arthritis better manage their injectable biotherapy drugs. 71 patients took part. The goal was to see if the training improved patients' knowledge and safety skills, so they could avoid side …
Phase: NA • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Disease control
Last updated Jun 16, 2026 12:50 UTC
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Old drug, new hope: thalidomide tackles rare mast cell cancer
Disease control CompletedThis study tested the drug thalidomide in people with a rare disease called systemic mastocytosis, where too many mast cells build up in the body. The goal was to see if thalidomide could shrink the disease by cutting off its blood supply. The trial included adults whose disease …
Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Disease control
Last updated Jun 15, 2026 19:08 UTC
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Gene test may improve drug dosing for kidney transplant patients
Disease control CompletedThis study looked at whether adjusting the dose of the anti-rejection drug tacrolimus based on a patient's genetic makeup could help achieve better drug levels in the blood after a kidney transplant. About 280 adult kidney transplant recipients took part. Researchers compared sta…
Phase: PHASE4 • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Disease control
Last updated Jun 15, 2026 19:06 UTC
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Antibiotics after gallbladder surgery may not be necessary
Disease control CompletedThis study looked at whether giving antibiotics after gallbladder removal surgery for mild to moderate gallstone inflammation helps prevent infections. Over 400 adults who had early surgery were followed for 30 days. The goal was to see if antibiotics reduce surgical site or othe…
Phase: PHASE3 • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Disease control
Last updated Jun 15, 2026 19:04 UTC
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Can adjusting hemoglobin levels improve life for kidney transplant patients?
Disease control CompletedThis study looked at 128 kidney transplant patients with chronic graft dysfunction and anemia. Researchers compared two different hemoglobin levels to see which one better improved quality of life after 6 months and slowed kidney function decline over 24 months. The goal was to f…
Phase: PHASE4 • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Disease control
Last updated Jun 15, 2026 19:03 UTC
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Which drug works best for Hard-to-Treat lung infection?
Disease control CompletedThis study tested two different antibiotic combinations for people with a rare lung infection caused by M. xenopi bacteria. 92 adults received either clarithromycin or moxifloxacin along with two other drugs for 6 months. The main goal was to see which combination cleared the bac…
Phase: PHASE3 • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Disease control
Last updated Jun 15, 2026 18:57 UTC
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Sleeve surgery may help you walk better
Disease control CompletedThis study tested whether sleeve gastrectomy (a type of weight-loss surgery) improves walking ability in people with severe obesity. Researchers measured how far 99 participants could walk in 6 minutes before surgery and again 6 months after. They also checked quality of life usi…
Phase: PHASE3 • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Disease control
Last updated Jun 15, 2026 18:57 UTC
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New filter may calm inflammation after heart surgery
Disease control CompletedThis study tested whether using a special filter called Oxiris during heart-lung bypass surgery can reduce inflammation and improve blood flow in small blood vessels. 70 adults having planned heart surgery were included. The filter aims to remove inflammatory substances, potentia…
Phase: NA • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Disease control
Last updated Jun 15, 2026 18:56 UTC
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New hope for kidney patients: drug may tame harmful mineral hormone
Disease control CompletedThis study tested whether sevelamer carbonate, a non-calcium phosphate binder, can lower high levels of a hormone called FGF-23 in people with chronic kidney disease who are not yet on dialysis. High FGF-23 is linked to bone and heart problems. The trial enrolled 98 adults with m…
Phase: PHASE3 • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Disease control
Last updated Jun 12, 2026 12:08 UTC
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Breath test during surgery could save organs
Disease control CompletedThis study tested a new way to guide treatment during major surgery. By measuring the gases a patient breathes out, doctors can tell if the body's tissues are getting enough oxygen. 350 adults having abdominal, orthopedic, or vascular surgery were randomly assigned to standard ca…
Phase: NA • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Disease control
Last updated Jun 10, 2026 13:29 UTC
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New method helps heart surgery patients get off blood pressure drugs faster
Disease control CompletedThis study looked at a better way to stop the blood pressure drug norepinephrine in 130 adults after heart surgery. Patients had a condition called vasoplegic syndrome, which causes dangerously low blood pressure. The goal was to see if using a measure called dynamic arterial com…
Phase: PHASE3 • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Disease control
Last updated Jun 10, 2026 13:28 UTC
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Can a simple drug during surgery prevent complications?
Disease control CompletedThis study looked at giving a drug called norepinephrine early during major abdominal surgery to prevent low blood pressure. The goal was to see if this approach reduces organ problems and other complications after surgery. 500 adults aged 50 and older at higher risk took part. T…
Phase: PHASE3 • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Disease control
Last updated Jun 10, 2026 13:25 UTC
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Heart pouch closure may cut stroke risk in brain bleed survivors
Disease control CompletedThis study looked at a procedure to close a small pouch in the heart (the left atrial appendage) in 58 people with an irregular heartbeat (atrial fibrillation) who had previously had a brain bleed. These people cannot take standard blood thinners because of the bleeding risk. The…
Phase: NA • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Disease control
Last updated Jun 09, 2026 12:08 UTC
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New hope for rare blood cancer: aggressive combo therapy shows promise
Disease control CompletedThis study tested a multi-step treatment plan for people under 70 with a rare and aggressive blood cancer called primary plasma cell leukemia. The approach combined several types of chemotherapy with stem cell transplants (using the patient's own cells or a donor's) to try to con…
Phase: PHASE2 • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Disease control
Last updated Jun 08, 2026 13:10 UTC
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AI-Powered MRI could spot prostate cancer in half the time
Diagnosis CompletedThis study tested new deep learning (AI) methods to make prostate MRI scans faster and more accurate. Researchers compared the new AI-powered scans to standard scans in 34 people. The goal was to see if the AI scans could detect suspicious prostate nodules just as well, while cut…
Phase: NA • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Diagnosis
Last updated Jun 16, 2026 18:46 UTC
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Breath test could replace needles for blood disorder diagnosis
Diagnosis CompletedThis study tested a new method called CO-rebreathing to measure red blood cell mass in people with polycythemia, a condition where the body makes too many red blood cells. The goal was to see if this simple, non-invasive breath test works as well as the standard radioactive blood…
Phase: NA • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Diagnosis
Last updated Jun 16, 2026 12:50 UTC
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Brain scan reveals hidden cause of Post-Stroke memory loss
Diagnosis CompletedThis study tested whether a special PET scan using a radioactive tracer called Florbetapir can detect amyloid plaques in the brains of people who develop memory problems after a stroke. 92 adults aged 40-80 with a recent stroke and cognitive issues were scanned to see how often a…
Phase: PHASE3 • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Diagnosis
Last updated Jun 15, 2026 19:05 UTC
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AI-Powered Ultra-Low dose CT matches standard scans for lung nodules
Diagnosis CompletedThis study tested whether a CT scan using very low radiation and artificial intelligence can detect lung nodules as accurately as a standard low-dose CT. 70 adults who needed a chest CT for lung nodule check-up or follow-up took part. The goal was to see if the new method could r…
Phase: NA • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Diagnosis
Last updated Jun 15, 2026 19:04 UTC
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New PET technique may solve brain scan dilemma
Diagnosis CompletedThis small pilot study tested whether an early, fast F-DOPA PET scan can help doctors tell the difference between a brain tumor coming back and damage from radiation therapy. Eight adults with brain metastases who were already scheduled for a PET scan took part. The goal was to s…
Phase: NA • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Diagnosis
Last updated Jun 15, 2026 18:55 UTC
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New imaging tool could speed up diagnosis of blood clotting disorders
Diagnosis CompletedThis study tested a new method using imaging flow cytometry to diagnose platelet disorders and heparin-induced thrombocytopenia (HIT). Researchers compared this technique with standard lab tests in 31 patients. The goal was to see if the new method is as good or better at detecti…
Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Diagnosis
Last updated Jun 15, 2026 18:54 UTC
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New ultrasound technique could spare pregnant women an invasive exam
Diagnosis CompletedThis study tested whether a noninvasive ultrasound done on the belly (transperineal) can accurately measure cervical length in pregnant women, compared to the standard internal ultrasound. The goal is to find a less uncomfortable way to check for risk of early labor. 85 women in …
Phase: NA • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Diagnosis
Last updated Jun 09, 2026 12:07 UTC
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New breathing trick sharpens lung cancer scans
Diagnosis CompletedThis study tested a new method for PET scans that tracks breathing to get clearer images of lung tumors. 103 adults with small lung nodules took part. The goal was to see if this technique helps doctors find and measure lung cancer more accurately.
Phase: NA • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Diagnosis
Last updated Jun 08, 2026 13:08 UTC
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Vitamin c may stop chronic pain after surgery
Prevention CompletedThis study looked at whether taking vitamin C can prevent a painful condition called Complex Regional Pain Syndrome (CRPS) type 1 after planned upper limb surgery. About 995 adults took part. The goal was to see if vitamin C, given before and after surgery, reduces the chance of …
Phase: PHASE3 • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Prevention
Last updated Jun 16, 2026 12:53 UTC
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Pill vs. gel: which speeds up labor safely?
Symptom relief CompletedThis study compared two medicines used to start labor in pregnant women at full term with an unready cervix. One group received an oral misoprostol pill, the other a vaginal dinoprostone gel or insert. Researchers tracked how many women delivered vaginally within 24 hours, rates …
Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Symptom relief
Last updated Jun 16, 2026 18:47 UTC
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Walk away fatigue: new study tests simple exercise for breast cancer patients
Symptom relief CompletedThis study looked at whether a supervised or distance-guided walking program could help manage fatigue in breast cancer patients undergoing hormone therapy. Seventeen women participated in a 6-week brisk walking program twice a week. The goal was to see if this simple activity co…
Phase: NA • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Symptom relief
Last updated Jun 16, 2026 12:54 UTC
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Bridge device for stoma: help or hindrance?
Symptom relief CompletedThis study looked at whether placing a bridge device during ileostomy surgery helps prevent problems like infections or skin irritation. 166 adults having planned colorectal surgery with an ileostomy took part. The goal was to see if the device reduces complications and makes car…
Phase: NA • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Symptom relief
Last updated Jun 16, 2026 12:52 UTC
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Eye drop gel shows promise for stubborn leg ulcers
Symptom relief CompletedThis study tested whether a gel made from timolol, a drug usually used in eye drops, can help heal chronic leg ulcers caused by poor vein circulation. 42 adults with ulcers that had not healed after at least 24 weeks of standard care were enrolled. For 12 weeks, half received sta…
Phase: PHASE2 • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Symptom relief
Last updated Jun 15, 2026 19:08 UTC
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Nerve block vs. muscle relaxant: which works better for laparoscopic surgery?
Symptom relief CompletedThis study compared two methods to relax the abdominal muscles during laparoscopic (keyhole) digestive surgery. One method uses a nerve block (TAP block) and the other uses a standard muscle relaxant (curare). The goal was to see which provides better muscle relaxation, measured …
Phase: PHASE4 • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Symptom relief
Last updated Jun 15, 2026 19:06 UTC
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Which nerve block wins for post-surgery pain? study reveals top contender.
Symptom relief CompletedThis study tested three different numbing methods to reduce pain after chest surgery (thoracoscopy). 155 adults were randomly assigned to receive one of three nerve blocks before surgery. The goal was to see which method worked best for controlling pain right after the operation.
Phase: PHASE3 • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Symptom relief
Last updated Jun 15, 2026 18:57 UTC
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New study tests nighttime breathing strategies to help COPD patients break free from ventilators
Symptom relief CompletedThis study tested two different ways of using a breathing machine during the night to help people with COPD stop relying on the machine. 19 patients in the hospital took part. The goal was to see which method helped them breathe on their own faster and sleep better.
Phase: NA • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Symptom relief
Last updated Jun 15, 2026 18:55 UTC
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Hope for tardive dyskinesia: tetrabenazine put to the test
Symptom relief CompletedThis study tested whether tetrabenazine (Xenazine) can reduce abnormal, involuntary movements in people with tardive dyskinesia, a condition caused by long-term use of antipsychotic medications. Fifty-four adults took either the drug or a placebo for 10 weeks. The goal was to see…
Phase: PHASE3 • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Symptom relief
Last updated Jun 12, 2026 12:06 UTC
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Can a simple shot treat tough bone infections?
Symptom relief CompletedThis study tested if giving the antibiotic teicoplanin as a shot under the skin is safe for treating bone and joint infections. Thirty adults with infections that were resistant to other antibiotics took part. The main goal was to see how well the shot was tolerated at the inject…
Phase: PHASE2 • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Symptom relief
Last updated Jun 12, 2026 12:05 UTC
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Same-Day appendix surgery: a new normal for mild cases?
Symptom relief CompletedThis study looked at whether adults with mild appendicitis can safely go home within 12 hours after surgery instead of staying overnight in the hospital. 120 patients were enrolled, and the main goal was to see how many could be discharged the same day. The results help doctors u…
Phase: PHASE3 • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Symptom relief
Last updated Jun 11, 2026 12:11 UTC
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Which numbing drug works best for leg surgery?
Symptom relief CompletedThis study compared two numbing medicines (levobupivacaine and ropivacaine) given as a spinal injection for leg surgery. 50 adults took part to see which medicine numbed the leg longer and affected movement less. The goal was to find the better option for pain control during surg…
Phase: PHASE4 • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Symptom relief
Last updated Jun 11, 2026 12:09 UTC
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Obesity surgery goes Day-Case: no overnight stay needed?
Symptom relief CompletedThis study tested whether a common weight-loss surgery (laparoscopic sleeve gastrectomy) could be safely performed as a day-case procedure, meaning patients go home the same day. Thirty adults with obesity were enrolled, and researchers tracked how many needed an unexpected overn…
Phase: NA • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Symptom relief
Last updated Jun 11, 2026 12:09 UTC
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New questionnaire helps track how COPD patients feel on treatment
Symptom relief CompletedThis study looked at whether a simple questionnaire called VQ11 can measure changes in quality of life for people with COPD who start a new long-acting bronchodilator. Fifty-seven adults with stable COPD (no recent flare-ups) filled out the VQ11 before and after three months of t…
Phase: NA • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Symptom relief
Last updated Jun 11, 2026 12:09 UTC
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Relaxation shows promise for fibromyalgia pain relief
Symptom relief CompletedThis study tested whether relaxation therapy can improve the overall well-being of people with fibromyalgia, a condition causing widespread chronic pain. Eighty adults with fibromyalgia were randomly assigned to either relaxation sessions or a placebo for 12 weeks. The main goal …
Phase: PHASE3 • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Symptom relief
Last updated Jun 10, 2026 13:31 UTC
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Experimental drug shows promise for botulism breathing problems
Symptom relief CompletedThis pilot study tested a drug called 3,4-diaminopyridine (FIRDAPSE) in 3 people with severe botulism who needed a breathing machine. The goal was to see if the drug could improve muscle and breathing function. Researchers measured changes in electrical signals from muscles and b…
Phase: PHASE2, PHASE3 • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Symptom relief
Last updated Jun 08, 2026 13:10 UTC
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New study aims to unlock mystery of low platelets in seniors
Knowledge-focused CompletedThis study looked at 37 adults over 60 with low blood platelets (less than 100 G/L) to see which tests best predict immune thrombocytopenia (ITP). Researchers compared bone marrow tests, blood tests for platelet antibodies, and other measures. The goal was to improve diagnosis an…
Phase: NA • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 16, 2026 18:48 UTC
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Decades of data reveal treatment shifts in kids with IBD
Knowledge-focused CompletedThis study examined medical records of 966 children diagnosed with Crohn's disease or ulcerative colitis between 1988 and 2011. Researchers wanted to see if newer treatments like immunosuppressants and anti-TNF drugs changed how many children needed surgery. The study did not tes…
Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 16, 2026 18:48 UTC
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Anesthesia choice may change tissue sample size in cervical procedure
Knowledge-focused CompletedThis study looked at 107 women having a first-time cervical procedure (LEEP) for abnormal cells. Researchers compared local anesthesia (cervical block) versus general or spinal anesthesia to see if it changed the size of the tissue removed. The goal was to understand if the type …
Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 16, 2026 18:48 UTC
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Could a common virus explain mysterious rashes in blood cancer patients?
Knowledge-focused CompletedThis study checked for the HHV6 virus in the skin and blood of 37 adults with blood cancers who developed a rash. The goal was to see how often the virus is present and whether it might be causing the rash. If a link is found, it could help doctors diagnose and treat these rashes…
Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 16, 2026 18:47 UTC
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Scientists compare brain tumors in kids and young adults to find key differences
Knowledge-focused CompletedThis study looked at medical records of 128 people treated for brain gliomas at a French hospital between 2008 and 2020. Researchers compared the genetic makeup, MRI scans, and outcomes of children (0-14 years) with those of adolescents and young adults (15-25 years). The goal wa…
Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 16, 2026 18:47 UTC
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Rumination's role in fibromyalgia: new insights from french study
Knowledge-focused CompletedThis study looked at how repetitive negative thinking, called rumination, affects the emotional and mental health of people with fibromyalgia. Researchers measured rumination and depression levels in 107 adults with fibromyalgia using questionnaires. The goal was to better unders…
Phase: NA • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 16, 2026 18:47 UTC
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Scientists map facial movements to improve surgery outcomes
Knowledge-focused CompletedThis study aims to better understand how facial muscles work during expressions like smiling. Researchers will use MRI scans and motion capture technology to measure both the surface skin movements and the deeper muscle movements. The goal is to create a computer model that helps…
Phase: NA • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 16, 2026 18:47 UTC
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Bipolar brain struggles to read faces, study finds
Knowledge-focused CompletedThis study looked at how people with bipolar disorder types I and II recognize emotions on others' faces, compared to healthy individuals. Ten adults with stable bipolar disorder and healthy controls took a facial emotion recognition test. The goal was to understand differences b…
Phase: NA • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 16, 2026 18:46 UTC
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Blood marker may reveal bone damage in myeloma
Knowledge-focused CompletedThis study looked at whether a substance in the blood called M-CSF can help doctors find bone damage in people with multiple myeloma. Researchers compared M-CSF levels in 111 people: those with multiple myeloma, those with a pre-cancer condition called MGUS, and healthy volunteer…
Phase: NA • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 16, 2026 18:46 UTC
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Could a vitamin B12 derivative help treat shock?
Knowledge-focused CompletedThis study looked back at medical records of 18 intensive care patients who received hydroxocobalamin (a form of vitamin B12) for severe vasodilatory shock, a condition where blood vessels widen too much and blood pressure drops dangerously. The goal was to see if the treatment c…
Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 16, 2026 12:54 UTC
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Stomach size after sleeve surgery: key to weight loss failure?
Knowledge-focused CompletedThis study looked at 90 people who had sleeve gastrectomy surgery for obesity but did not lose enough weight. Researchers measured the size of the remaining stomach two years after surgery to see if a larger stomach caused the failure. The goal was to find a way to improve treatm…
Phase: NA • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 16, 2026 12:54 UTC
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Kidney patients may safely take common diabetes drug, study hints
Knowledge-focused CompletedThis study looked at whether the diabetes drug metformin can be used safely in people with all stages of kidney disease (stages 1-5). About 82 diabetic patients with stable kidney function were given increasing doses of metformin. Researchers measured the drug level in red blood …
Phase: PHASE2 • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 16, 2026 12:54 UTC
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Video beats the eye: new method for checking blood flow in ICU patients
Knowledge-focused CompletedThis study tested whether using a video to measure how quickly skin color returns after pressure (capillary refill time) is more reliable than the usual visual method. Researchers studied 59 adults in the intensive care unit. The goal was to see if the video method gives more con…
Phase: NA • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 16, 2026 12:54 UTC
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New MRI method could spot reversible dementia earlier
Knowledge-focused CompletedThis study looked at a type of dementia caused by fluid buildup in the brain, which can be reversed with a shunt. The goal was to create a better way to diagnose it by combining pressure and flow measurements from MRI and fluid tests. Researchers studied 75 people over age 55 wit…
Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 16, 2026 12:53 UTC
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Massive french study reveals gaps in liver cancer detection
Knowledge-focused CompletedThis study looked at health records of over 75,000 people with cirrhosis in France to see if doctors are following guidelines for early detection of liver cancer. The goal was to find out how often screening is done correctly and what factors might lead to missed or delayed diagn…
Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 16, 2026 12:53 UTC
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Heart imaging showdown: which ultrasound is better during surgery?
Knowledge-focused CompletedThis study looked at 90 adults having planned heart surgery to see if two types of ultrasound—one on the chest and one down the throat—give the same measurement of right heart function. The goal was to check if these methods can be used interchangeably during surgery. No new trea…
Phase: NA • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 16, 2026 12:53 UTC
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Ultrasound vs. blind stick: which works better for ICU artery access?
Knowledge-focused CompletedThis study looked at whether using ultrasound to guide arterial catheter placement in intensive care patients improves success on the first try and reduces complications. Researchers enrolled 288 adults in the ICU who needed an arterial line. The goal was to see if ultrasound mak…
Phase: NA • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 16, 2026 12:52 UTC
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New study checks if sending new moms home early is safe
Knowledge-focused CompletedThis study looked at what happens to mothers and their newborns in the first month after going home from the hospital earlier than usual. It included 177 mothers and babies who were sent home after a short hospital stay. The goal was to see if early discharge leads to any health …
Phase: NA • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 16, 2026 12:51 UTC
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Heart surgery transfusion study: smarter blood use?
Knowledge-focused CompletedThis study tested a new way to decide when to give blood transfusions after heart surgery. Instead of using a fixed hemoglobin level, doctors used a measure of oxygen in the blood (ScvO2) to guide transfusions. The goal was to see if this approach could reduce unnecessary transfu…
Phase: NA • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 16, 2026 12:51 UTC
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New MRI technique could sharpen diagnosis of torn knee ligaments
Knowledge-focused CompletedThis study tested a new MRI method called diffusion tractography to better measure how badly the anterior cruciate ligament (ACL) in the knee is torn. Researchers enrolled 30 adults who had a knee MRI after an injury. The goal was to see if this technique could give a more precis…
Phase: NA • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 16, 2026 12:51 UTC
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AI lets heart patients breathe easy during MRI scans
Knowledge-focused CompletedThis study tested whether a new MRI technique using artificial intelligence (deep learning) can accurately measure heart function while patients breathe normally, instead of holding their breath. 54 adults with ischemic heart disease took part. The goal was to see if the AI metho…
Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 16, 2026 12:49 UTC
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Plastic bag trick may protect tiny babies from dangerous cold
Knowledge-focused CompletedThis study tested whether wrapping preterm babies in a polyethylene bag during central line placement helps prevent dangerous drops in body temperature. The procedure can take 30 minutes to 2 hours, and opening the incubator causes heat loss. Researchers measured temperature chan…
Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 16, 2026 12:49 UTC
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New ultrasound technique may spot hidden heart risks after lung surgery
Knowledge-focused CompletedThis study tested a new ultrasound method to detect right heart problems after lung surgery. Researchers followed 191 adults who had lung surgery and used a special heart ultrasound technique to see if it could predict serious heart complications like irregular heartbeat or heart…
Phase: NA • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 16, 2026 12:48 UTC
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Storytime for preemies: a simple way to strengthen Mom-Baby bond?
Knowledge-focused CompletedThis study looked at whether reading stories to premature babies in the hospital helps improve the connection between mother and baby. Researchers measured heart and breathing patterns in 27 mothers and their preterm infants to see if storytime made their rhythms more in sync. Th…
Phase: NA • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 16, 2026 12:48 UTC
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Many heart patients skip their blood thinners – study aims to find out why
Knowledge-focused CompletedThis study looked at how well 883 adults with atrial fibrillation take their prescribed blood-thinning medication (DOACs) to prevent strokes. Researchers interviewed patients at their pharmacy when they came to refill their prescription. The goal was to measure adherence and crea…
Phase: NA • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 15, 2026 19:08 UTC
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New MRI technique maps liver blood flow in 3D
Knowledge-focused CompletedThis study tested a new 4D MRI technique to measure blood flow in the liver. 44 adults who fasted before the scan took part. The goal was to see if the method gives consistent results for blood flow in the liver's main vessels. This is a research study to improve imaging, not a t…
Phase: NA • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 15, 2026 19:08 UTC
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Tiny genetic clues in carotid plaques could predict stroke risk
Knowledge-focused CompletedThis study looked at small molecules called microRNAs in the blood and in fatty plaques removed from the carotid arteries of 14 adults during surgery. The goal was to see if certain microRNAs could serve as new biomarkers to better understand and track carotid artery disease. The…
Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 15, 2026 19:08 UTC
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Could a virus spark Graves' disease? new study investigates parvovirus link
Knowledge-focused CompletedThis study explored whether infection with parvovirus might trigger Graves' disease, an autoimmune condition affecting the thyroid. Researchers compared 52 participants: those recently diagnosed with Graves' disease and a control group with other thyroid issues. The goal was to s…
Phase: NA • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 15, 2026 19:08 UTC
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Blood clot marker may forecast stroke recovery
Knowledge-focused CompletedThis study looked at 102 stroke patients to see if a blood test for D-dimer (a clot breakdown product) could predict how well they recover after treatment. Researchers compared D-dimer levels with standard disability scores (NIHSS and Rankin) measured months later. The goal was t…
Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 15, 2026 19:07 UTC
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Drones deliver blood samples in first-of-its-kind hospital test
Knowledge-focused CompletedThis study tested whether drones can safely transport blood samples between hospitals without damaging them. Thirty adult volunteers provided blood samples that were shipped by drone and by ground transport, then compared for temperature, timing, and physical condition. The goal …
Phase: NA • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 15, 2026 19:07 UTC
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Hospital study: does surgery priority system save lives?
Knowledge-focused CompletedThis study tested if a system that ranks emergency surgeries by urgency leads to better results. Researchers tracked 756 adults who had non-cardiac emergency surgery. They wanted to see if delays beyond the recommended time for each urgency level increased complications or deaths…
Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 15, 2026 19:06 UTC
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Hidden waves: do NICU machines affect preemie brains?
Knowledge-focused CompletedThis study looked at whether the constant low-level radio waves from medical devices in the NICU affect the brain development of premature babies. Researchers measured each baby's exposure over 6 weeks and tracked their sleep, brain blood flow, and heart activity. The goal was to…
Phase: NA • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 15, 2026 19:06 UTC
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Heat-Sensing camera could spot Crohn's Flare-Ups in kids without needles or scopes
Knowledge-focused CompletedThis study tested whether a special thermal camera can detect inflammation in the guts of children with Crohn disease by measuring heat patterns on their belly. 43 children aged 4 to 17 took part. The goal was to see if this quick, painless method could replace or reduce the need…
Phase: NA • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 15, 2026 19:05 UTC
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MRI may replace spinal tap for brain surgery decisions
Knowledge-focused CompletedThis study looked at whether a special MRI scan (flow MRI) can predict if surgery will help people with normal pressure hydrocephalus, a condition where fluid builds up in the brain. Currently, doctors use a spinal tap to make this prediction. The study enrolled 30 adults and mea…
Phase: EARLY_PHASE1 • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 15, 2026 19:05 UTC
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COVID-19's hidden toll on the brain revealed by new MRI study
Knowledge-focused CompletedThis study looked at 21 COVID-19 patients who had neurological symptoms like loss of smell, headache, or memory problems. Researchers used advanced MRI scans to detect brain changes. The goal was to better understand how the virus can affect the brain, not to test a treatment.
Phase: NA • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 15, 2026 19:05 UTC
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Painkiller combo studied for safer surgery recovery
Knowledge-focused CompletedThis study looked at how two pain medicines, lidocaine (given through a vein) and ropivacaine (given through a small tube in the back), affect each other's levels in the blood during major abdominal surgery. The goal was to see if using them together is safe and could reduce side…
Phase: PHASE4 • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 15, 2026 19:05 UTC
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Back crack secrets revealed: study probes muscle effects
Knowledge-focused CompletedThis study looked at how a type of hands-on therapy (specific back mobilizations) affects muscle activity in the back. 156 healthy adults took part. The goal was to understand the therapy's effects on muscle control, separate from placebo or natural changes.
Phase: NA • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 15, 2026 19:05 UTC
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ER mystery: do patients actually do what doctors say?
Knowledge-focused CompletedThis study looked at whether patients follow the advice they get when leaving the emergency room. Researchers called 242 adults a week after their ER visit to check if they followed discharge orders. The goal was to understand compliance, not to test a new treatment.
Phase: NA • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 15, 2026 19:05 UTC
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Can a simple blood test spot hidden fungal infections in the gut?
Knowledge-focused CompletedThis study looked at whether a substance called β-D-glucan in the blood can help doctors diagnose and monitor fungal infections in the abdomen (peritonitis). Researchers measured daily levels in 70 intensive care patients with and without yeast infections. The goal was to see if …
Phase: NA • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 15, 2026 19:04 UTC
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Cancer patients face more side effects from rare lung infection treatment
Knowledge-focused CompletedThis study looked at 41 people treated for a lung infection called NTM, comparing those with and without cancer. The goal was to see if cancer patients had more side effects from the treatment, which might explain why they often stop it early. Researchers reviewed past medical re…
Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 15, 2026 19:03 UTC
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Can a simple test tell if kidneys will recover from septic shock?
Knowledge-focused CompletedThis study looked at 184 adults with septic shock and early kidney injury to see if a test called Nephrocheck could predict whether their kidneys would recover within 72 hours. The goal was to help doctors know which patients might get better on their own. The study did not test …
Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 15, 2026 19:03 UTC
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New MRI technique aims to replace risky heart catheter for lung pressure check
Knowledge-focused CompletedThis study tested whether a special MRI scan (4D flow MRI) can accurately measure blood pressure in the lungs, avoiding the need for a heart catheterization, which carries small risks. Twenty-eight adults with pulmonary hypertension had the MRI, a heart catheter, and an ultrasoun…
Phase: NA • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 15, 2026 19:03 UTC
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Does age matter? study links timing of cervical surgery to pregnancy risks
Knowledge-focused CompletedThis study looked at whether the age at which a woman had cervical conization (surgery to remove precancerous cells) affects the length of her cervix during a later pregnancy. A shorter cervix can increase the risk of early delivery. Researchers measured cervix length in pregnant…
Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 15, 2026 19:03 UTC
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AI spots unnecessary hospital days for seniors
Knowledge-focused CompletedThis study looked at whether a computer program could help predict when older patients (over 75) are ready to leave the hospital. Researchers analyzed electronic health records from 102 patients to see if natural language processing could identify unnecessary hospital stays. The …
Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 15, 2026 19:03 UTC
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HIV Patients' thyroid health under the microscope
Knowledge-focused CompletedThis study looked at how often thyroid problems (specifically an underactive thyroid) occur in people with HIV. Researchers reviewed medical records of 154 HIV-positive adults who were treated at a French hospital between 2001 and 2012. The goal was to get a clearer picture of th…
Phase: NA • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 15, 2026 19:03 UTC
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Healthy volunteers get IV fluids to reveal liver's hidden blood flow secrets
Knowledge-focused CompletedThis study looked at how the liver's blood supply changes when healthy people receive extra fluids through an IV. Researchers used MRI to measure blood flow in the liver's main vessels before and after giving 500 ml of saline. The goal was to understand the liver's natural 'buffe…
Phase: NA • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 15, 2026 19:02 UTC
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Green dye could make gallbladder surgery safer and faster
Knowledge-focused CompletedThis study tested whether using a green dye (indocyanine green) during gallbladder removal surgery helps surgeons see bile ducts better than the standard X-ray method. The goal was to reduce the risk of bile duct injury and shorten surgery time. The study involved 156 adults with…
Phase: NA • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 15, 2026 18:59 UTC
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Heart surgery study peers into blood Vessel's 'Sugary Shield'
Knowledge-focused CompletedThis study looked at a thin sugar-and-protein layer inside blood vessels, called the glycocalyx, which helps control fluid leakage. In 28 heart surgery patients, researchers measured proteins from this layer in blood samples. The goal was to better understand why fluid leaks out …
Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 15, 2026 18:56 UTC
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Scientists watch baby brains grow: preterm vs. Full-Term language development
Knowledge-focused CompletedThis study looked at how babies' brains become specialized for language, comparing preterm and full-term newborns. Researchers used EEG and NIRS to measure brain activity while babies heard sounds. The goal was to understand when and where language dominance develops, and how a p…
Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 15, 2026 18:56 UTC
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Lung ultrasound may help surgeons give just the right amount of fluids
Knowledge-focused CompletedThis study tested whether a lung ultrasound can help doctors give the right amount of fluids during surgery. 200 adults having various surgeries were monitored. The goal was to see if the ultrasound could detect early signs of fluid overload, which could help avoid complications.…
Phase: NA • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 15, 2026 18:56 UTC
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Drunk patients Can't guess their BAC: study reveals big gap
Knowledge-focused CompletedThis study looked at 34 people who came to the emergency department with alcohol intoxication. Researchers asked them to estimate their own blood alcohol concentration and then compared it to a real breath or blood test. The goal was to see if people tend to underestimate their l…
Phase: NA • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 15, 2026 18:56 UTC
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Lab-Grown skin could predict best melanoma drugs
Knowledge-focused CompletedThis study aimed to create 3D models of melanoma tumors using human skin to test which drug combinations work best for each patient. Researchers collected skin metastases from one participant and grew them in the lab. The goal was to find a way to predict treatment response and r…
Phase: NA • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 15, 2026 18:56 UTC
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Can a simple calculation replace a lab test for testosterone?
Knowledge-focused CompletedThis study looked at whether a mathematical formula can accurately measure bioavailable testosterone, instead of using a special lab test called radioimmunoassay (RIA). The researchers wanted to see if the two methods give similar results. 270 men and women aged 18 to 90 took par…
Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 15, 2026 18:55 UTC
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Researchers seek clearer diagnosis for rare inflammatory diseases
Knowledge-focused CompletedThis study looked back at 210 patients with aortitis (inflammation of the main artery) or retroperitoneal fibrosis (scar tissue in the abdomen) to find better ways to diagnose these conditions. The goal is to help doctors tell different types apart more accurately, which could le…
Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 15, 2026 18:55 UTC
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Ultrasound may make ICU breathing tubes safer
Knowledge-focused CompletedThis study looked at whether using ultrasound to guide a tracheostomy (a breathing tube placed in the neck) in the ICU is safe and practical. Researchers tracked complications like bleeding, tube misplacement, or injury in 40 adult patients. The goal was to see if this approach c…
Phase: NA • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 15, 2026 18:54 UTC
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Foot pulse test may foretell limb and heart danger
Knowledge-focused CompletedThis study looked at 134 people with severe peripheral artery disease (blocked leg arteries causing pain or wounds). Researchers measured blood flow in the foot using a new method called Systolic Rise Time. The goal was to see if this measurement could predict future major limb p…
Phase: NA • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 15, 2026 18:54 UTC
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Can a common diabetes drug work safely in kidney patients?
Knowledge-focused CompletedThis study tested the safety and effectiveness of a once-daily form of metformin (metformin XR) in 12 adults with type 2 diabetes and mild to moderate chronic kidney disease. Researchers measured blood sugar levels continuously and checked kidney and lactate levels over 12 weeks.…
Phase: PHASE2 • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 15, 2026 18:54 UTC
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New study maps brain changes after stroke to predict memory loss
Knowledge-focused CompletedThis study looked at how often thinking, memory, and behavior problems happen six months after a stroke. Researchers tested over 1,600 French-speaking adults (906 healthy controls and 302 stroke patients) using a new set of thinking and memory tests. The goal was to create standa…
Phase: NA • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 12, 2026 12:08 UTC
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Bone probe breakthrough: doctors test new way to monitor reconstructed jaws
Knowledge-focused CompletedThis study tested whether a small monitoring probe (microdialysis catheter) placed directly into the bone can reliably measure the health of bone flaps used in head and neck reconstruction. 34 adults having surgery with bone from the hip or leg took part. The goal was to see if t…
Phase: NA • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 12, 2026 12:08 UTC
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Could DNA in the blood predict IVF success in endometriosis patients?
Knowledge-focused CompletedThis study looked at whether tiny pieces of DNA floating in the blood and egg follicle fluid are higher in women with endometriosis who are doing IVF. Researchers compared 114 women with and without endometriosis to see if these DNA levels relate to egg quality and pregnancy resu…
Phase: NA • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 12, 2026 12:07 UTC
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MRI scans eye blood flow to uncover glaucoma clues
Knowledge-focused CompletedThis study used MRI to measure blood flow in the eye's main artery in 20 adults with untreated glaucoma and healthy controls. The goal was to understand how blood flow problems may contribute to glaucoma damage. No treatment was given; it was purely an observational imaging study…
Phase: NA • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 12, 2026 12:07 UTC
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Antibiotic penetration in chest infections measured
Knowledge-focused CompletedThis study looked at how the antibiotics amoxicillin and clavulanic acid get into the fluid around the lungs in people with serious chest infections. Eleven adults who needed a chest tube took part. The goal was to learn more about how these drugs work in the body, not to test a …
Phase: NA • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 12, 2026 12:06 UTC
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Tiny brains, big discovery: preterm infants' voice recognition studied
Knowledge-focused CompletedThis study looked at how preterm babies' brains develop the ability to recognize their mother's voice. Researchers measured brain activity in 22 premature infants to see which side of the brain processes voices. The goal was to understand how early sound exposure affects brain de…
Phase: NA • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 12, 2026 12:05 UTC
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Can a simple ultrasound spot hidden fluid in dialysis patients?
Knowledge-focused CompletedThis study looked at whether lung ultrasound can accurately measure excess fluid in people receiving hemodialysis. 46 adults on dialysis were checked before their session. The goal was to see if this quick, non-invasive test could help doctors better manage fluid removal during t…
Phase: NA • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 11, 2026 12:11 UTC
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Sleep apnea may be hiding in type 1 diabetes patients
Knowledge-focused CompletedThis study looked at how often sleep apnea occurs in adults with type 1 diabetes. Researchers monitored 53 participants overnight with sleep tests and continuous blood sugar tracking. The goal was to find out how many have sleep apnea and whether it affects blood sugar control.
Phase: NA • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 11, 2026 12:11 UTC
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Fungus in lungs linked to worse COPD symptoms?
Knowledge-focused CompletedThis study followed 100 people with severe COPD to see if the presence of aspergillus fungus in their sputum is linked to worse quality of life and breathing problems. Participants provided sputum samples and filled out questionnaires at the start, then again by phone after 1 and…
Phase: NA • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 11, 2026 12:10 UTC
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Amiens study: a simple chat boosts exercise in chronic illness patients
Knowledge-focused CompletedThis study looked at whether a special type of conversation, called motivational interviewing, helps people with long-term illnesses stick to an exercise program. 114 adults with chronic conditions in Amiens, France, were split into two groups: one got the motivational talk plus …
Phase: NA • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 11, 2026 12:09 UTC
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Transplant lifesaver linked to cancer risk: study investigates
Knowledge-focused CompletedThis study looked at 2,500 kidney transplant patients to find out why some develop cancer. The main focus was on the immunosuppressive drugs that prevent organ rejection, which can also raise cancer risk. Researchers tracked patients from four regions in France over 10 years to i…
Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 11, 2026 12:09 UTC
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Blood protein may forecast kidney failure in septic shock
Knowledge-focused CompletedThis study looked at whether levels of a protein called vasorin in the blood can help predict how severe kidney injury will be in people with septic shock. Researchers measured vasorin in 50 intensive care patients and checked if it was linked to death or long-term kidney problem…
Phase: NA • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 11, 2026 12:09 UTC
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Are preterm babies getting too many transfusions?
Knowledge-focused CompletedThis study looked at 201 very premature babies born before 31 weeks to see if they received more red blood cell transfusions than recommended by 2014 guidelines. The goal was to understand why extra transfusions happen and how to reduce risks like digestive, eye, lung, and brain …
Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 10, 2026 13:29 UTC
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Robot lends a hand in delicate ear surgery
Knowledge-focused CompletedThis study tested a robot-assisted surgical method for cochlear implants in 9 adults with severe hearing loss. The goal was to see if the robot could make the surgery safer and less invasive than the traditional microscope-based approach. Researchers measured surgery time and sur…
Phase: NA • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 10, 2026 13:27 UTC
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Skin glow test may spot hidden sexual health risk in diabetics
Knowledge-focused CompletedThis study looked at 97 men with type 2 diabetes to see if a non-invasive skin test (AGE Reader) could detect high levels of AGEs, which are linked to erectile dysfunction. The goal was to find a simple way to screen for sexual health problems and improve overall diabetes care. T…
Phase: NA • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 10, 2026 13:27 UTC
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New probe aims to catch deadly leaks after rectal surgery
Knowledge-focused CompletedThis study tested a technique called microdialysis to monitor for dangerous leaks after rectal cancer surgery. 21 patients had a small probe placed near the surgical connection to measure chemical changes. The goal was to see if the probe could spot leaks earlier than standard me…
Phase: PHASE3 • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 10, 2026 13:26 UTC
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Eye test could spot Alzheimer's early, study hints
Knowledge-focused CompletedThis study looked at whether thinning of the retina (the back part of the eye) can be a sign of Alzheimer's disease. Researchers compared eye scans from 55 people with Alzheimer's, Lewy body disease, and healthy volunteers. The goal was to see if measuring retinal layers could he…
Phase: NA • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 10, 2026 13:25 UTC
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Removing drains earlier after pancreatic surgery may cut infections
Knowledge-focused CompletedThis study looked at 141 people who had pancreatic surgery to remove a tumor. Doctors wanted to see if taking out the surgical drains early (4 days after surgery) instead of waiting the usual 10-15 days would lower the chance of wound or belly infections. Patients who did not hav…
Phase: NA • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 10, 2026 13:24 UTC
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New study tests newborns for pesticides in first poop
Knowledge-focused CompletedThis study looked at whether babies in the Picardie region of France are exposed to pesticides before birth. Researchers tested the baby's first stool and the mother's hair for pesticides, and asked mothers about their exposure. The goal was to see if pesticide exposure is linked…
Phase: NA • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 09, 2026 12:08 UTC
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Breech birth study challenges routine C-Sections
Knowledge-focused CompletedThis study looked at whether inducing labor is a safe option for women whose babies are in the breech position (feet or bottom first) at full term. Normally, these women are scheduled for a C-section. The goal was to see if offering labor induction could lower the risks of surger…
Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 09, 2026 12:07 UTC
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Scientists seek clues to leg ulcer healing in 104 patients
Knowledge-focused CompletedThis study followed 104 people with venous leg ulcers to see which factors helped them heal within 24 weeks. Researchers looked at medical history, wound size, and lifestyle. The goal was to find better ways to predict and support healing.
Phase: NA • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 09, 2026 12:06 UTC
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ACL surgery myth busted? new study tests old assumption
Knowledge-focused CompletedThis study tested whether the center of the ACL's natural attachment points is the best spot for surgical reconstruction. Researchers used 4D CT scans to measure how the distance between these points changes as the knee bends in 30 healthy volunteers. The goal is to gather data t…
Phase: NA • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 08, 2026 13:18 UTC
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Superbug outbreak in ICU during COVID: lessons learned
Knowledge-focused CompletedThis study looked at how a hospital intensive care unit (ICU) managed an outbreak of a hard-to-treat bacteria called VIM-producing Enterobacter cloacae during the COVID-19 pandemic. Researchers reviewed the cases of 14 ICU patients who had this bacteria between March and October …
Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 08, 2026 13:09 UTC
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New breathing technique may give surgeons more time during throat procedures
Knowledge-focused CompletedThis study tested whether using a machine to help patients breathe (non-invasive ventilation) before a throat procedure allows more time without a drop in oxygen levels compared to normal breathing. Fifty adults scheduled for panendoscopy took part. The goal was to find a safer w…
Phase: NA • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 08, 2026 13:07 UTC
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Brain scans reveal how Parkinson's stimulation affects driving and impulse control
Knowledge-focused CompletedThis study looked at 15 people with Parkinson's disease who have a deep brain stimulation (DBS) device. Researchers used a special brain imaging technique to measure changes in brain activity while participants performed a hand movement task and an impulse control task, both with…
Phase: EARLY_PHASE1 • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 08, 2026 13:03 UTC
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New monitoring technique may spot preterm birth risk earlier
Knowledge-focused CompletedThis study looked at whether measuring the electrical activity of the uterus (called an electrohysterogram or EHG) can help doctors predict preterm birth in women hospitalized for threatened premature labor. Researchers monitored 100 pregnant women between 26 and 35 weeks of preg…
Phase: NA • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 05, 2026 12:09 UTC
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Study: ruminating on pain worsens mood after exercise in fibromyalgia
Knowledge-focused CompletedThis study looked at how thinking over and over about pain (rumination) affects mood after physical activity in people with fibromyalgia. 47 adults completed surveys about their emotions and pain levels. The goal was to see if rumination makes negative feelings worse after exerci…
Phase: NA • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 05, 2026 12:07 UTC
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Urine particles may reveal kidney disease secrets
Knowledge-focused CompletedThis study looked at tiny particles called extracellular vesicles found in urine to see if they can help tell the difference between healthy kidneys and chronic kidney disease. Researchers measured the number of these particles in 143 adults—some healthy and some with kidney prob…
Phase: NA • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 03, 2026 12:03 UTC
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Phosphorus pills studied in anorexic teens: hormone clues found
Knowledge-focused CompletedThis study explored how oral phosphorus supplements change levels of a hormone called FGF23 in 30 undernourished adolescents with anorexia. FGF23 helps control phosphate and calcium in the body. The goal was to understand the hormone's role during refeeding, not to treat the eati…
Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 02, 2026 11:39 UTC
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New pain monitor could cut morphine use in obesity surgery
Knowledge-focused CompletedThis study tested a device that measures pain during weight-loss surgery in 15 adults. The goal was to see if it helps doctors give less morphine. The study is complete, but results are not yet available.
Phase: NA • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 01, 2026 18:04 UTC
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Lying on your side or back? study finds best position for rectal exam
Knowledge-focused CompletedThis study looked at 320 men to see whether a digital rectal exam works better when the patient lies on their side or on their back. The goal was to find which position lets doctors feel the entire rectum and check the sphincter more fully. Results will help guide how this common…
Phase: PHASE3 • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 01, 2026 17:57 UTC
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Hidden antibodies in healthy blood donors may reveal heart disease clues
Knowledge-focused CompletedThis study examined over 1,200 healthy blood donors to see if certain antibodies (antiphospholipid antibodies) are linked to heart disease risk factors like high cholesterol or inflammation. Participants gave a blood sample and answered questions about their health. The goal is t…
Phase: NA • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 01, 2026 17:57 UTC
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Superbug watch: how common are Drug-Resistant gut bacteria in france?
Knowledge-focused CompletedThis study looked at how often certain gut bacteria (Enterobacteria) are resistant to a powerful group of antibiotics called carbapenems. Researchers tested samples from 287 patients in northwest France to find the rate of these resistant strains. The goal was to understand the p…
Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated May 26, 2026 12:00 UTC