Centre Hospitalier Universitaire, Amiens
Clinical trials sponsored by Centre Hospitalier Universitaire, Amiens, explained in plain language.
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New hope for rare blood cancer: aggressive combo therapy shows promise
Disease control CompletedThis study tested a multi-step treatment plan for 40 patients under 70 with primary plasma cell leukemia, a rare and aggressive blood cancer. The approach included several rounds of different chemotherapy drugs, followed by one or two stem cell transplants (using the patient's ow…
Phase: PHASE2 • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Disease control
Last updated Apr 29, 2026 03:26 UTC
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New PET scan technique may solve brain tumor mystery
Diagnosis CompletedThis study tested whether an early, quick F-DOPA PET scan can distinguish between a brain tumor coming back and damage from radiation therapy. Eight adults with brain metastases who were already scheduled for a PET scan took part. The goal was to see if measuring activity within …
Phase: NA • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Diagnosis
Last updated Apr 26, 2026 20:02 UTC
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Experimental drug shows promise for botulism breathing problems
Symptom relief CompletedThis pilot study tested a drug called 3,4-diaminopyridine in people with severe botulism who needed a ventilator to breathe. The goal was to see if the drug could improve muscle strength and breathing. Only 3 people took part, and researchers measured changes in nerve and muscle …
Phase: PHASE2, PHASE3 • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Symptom relief
Last updated Apr 26, 2026 20:03 UTC
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Same-Day appendix surgery: a safe option for simple cases?
Symptom relief CompletedThis study looked at whether people with uncomplicated appendicitis can safely have their appendix removed and go home the same day, instead of staying overnight in the hospital. Researchers followed 120 adults who had surgery and checked if they were discharged within 12 hours. …
Phase: PHASE3 • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Symptom relief
Last updated Apr 26, 2026 20:02 UTC
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Relaxation vs. placebo: a new hope for fibromyalgia sufferers?
Symptom relief CompletedThis study looked at whether relaxation therapy can improve the overall well-being of people with fibromyalgia, a condition causing widespread chronic pain. About 80 adults with fibromyalgia took part, receiving either relaxation sessions or a placebo for 12 weeks. The goal was t…
Phase: PHASE3 • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Symptom relief
Last updated Apr 26, 2026 20:01 UTC
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Which nerve block best eases pain after chest surgery?
Symptom relief CompletedThis study looked at 155 adults having chest surgery to find the best way to control pain. Patients received one of three nerve blocks before surgery. The goal was to see which method reduced pain the most after the operation.
Phase: PHASE3 • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Symptom relief
Last updated Apr 26, 2026 20:00 UTC
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Parkinson's brain study: what happens when stimulation is on vs. off?
Knowledge-focused CompletedThis study looked at 15 people with Parkinson's disease who have a deep brain stimulation device. Researchers used a special brain imaging technique to measure brain activity while participants did a hand movement task and a decision-making task. They compared brain activity when…
Phase: EARLY_PHASE1 • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Apr 29, 2026 03:28 UTC
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Back crack science: can spine mobilization boost muscle power?
Knowledge-focused CompletedThis study looked at how a specific type of hands-on therapy (mobilization) on the upper back affects the activity of back muscles in healthy people. 156 volunteers were split into three groups: one received the therapy, one received a placebo-like treatment, and one had no treat…
Phase: NA • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Apr 29, 2026 03:28 UTC
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Rectal exam showdown: back or side? study settles the debate
Knowledge-focused CompletedThis study looked at 320 men to find out if a digital rectal exam is more complete when the patient lies on their back (supine) or on their side (lateral decubitus). The goal was to see which position allows the doctor to feel the entire rectum and check the sphincter better. Res…
Phase: PHASE3 • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Apr 29, 2026 03:28 UTC
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New breathing technique may buy more time during cancer screening
Knowledge-focused CompletedThis study tested whether using a machine to help people breathe before an ENT cancer screening procedure could keep their oxygen levels safe for a longer time. Fifty adults scheduled for panendoscopy under general anesthesia took part. The goal was to see if the machine-assisted…
Phase: NA • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Apr 29, 2026 03:27 UTC
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Stomach size after sleeve surgery: key to weight loss failure?
Knowledge-focused CompletedThis study looked at 90 adults who had sleeve gastrectomy surgery for obesity but did not lose enough weight. Researchers measured the remaining stomach volume two years after surgery to see if a larger leftover stomach caused the failure. The goal is to help doctors decide on ne…
Phase: NA • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Apr 29, 2026 03:27 UTC
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Kidney patients may safely use common diabetes drug, study hints
Knowledge-focused CompletedThis study looked at whether the diabetes drug metformin can be used safely in people with type 2 diabetes who also have kidney disease (stages 1 to 5). Researchers measured metformin levels in red blood cells to see if they stayed within a safe range. About 82 patients took part…
Phase: PHASE2 • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Apr 29, 2026 03:27 UTC
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Drunk patients Can't guess their BAC, study finds
Knowledge-focused CompletedThis study looked at 34 people who came to the emergency department with alcohol intoxication. Researchers asked them to guess their blood alcohol concentration (BAC) and then compared that guess to a real breath or blood test. The goal was to see if people underestimate how drun…
Phase: NA • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Apr 29, 2026 03:27 UTC
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Do patients actually follow ER Doctor's orders? new study investigates
Knowledge-focused CompletedThis study looked at whether patients follow the instructions they receive when leaving the emergency room. Researchers called 242 adults a week after their ER visit to check. The goal was to understand how well people follow discharge advice, not to test a new treatment.
Phase: NA • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Apr 29, 2026 03:26 UTC
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New study tracks brain changes after stroke
Knowledge-focused CompletedThis study looked at how often people have thinking, memory, or behavior problems six months after a stroke. Researchers tested over 1,600 participants, including stroke patients and healthy volunteers, using a new French version of a standard cognitive test battery. The goal was…
Phase: NA • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Apr 29, 2026 03:26 UTC
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Scientists investigate why some leg ulcers heal and others Don't
Knowledge-focused CompletedThis study followed 104 people with venous leg ulcers to find out which factors help them heal within 24 weeks. Researchers looked at medical history, wound size, and even social and emotional factors. The goal was to better understand why some ulcers heal and others do not, with…
Phase: NA • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Apr 29, 2026 03:26 UTC
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ACL surgery may get a High-Tech upgrade: 4D scans challenge old assumptions
Knowledge-focused CompletedThis study tested whether the center of the ACL's natural attachment points keeps the ligament the same length as the knee bends. Thirty healthy volunteers had 4D scans to measure changes in distance between these points. The goal was to see if current surgical methods need impro…
Phase: NA • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Apr 29, 2026 03:25 UTC
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Drones to the rescue: can they deliver lab samples safely?
Knowledge-focused CompletedThis study tested whether drones can transport blood samples between hospitals without damaging them. Researchers flew samples between three hospitals in France and compared their condition to samples transported by traditional methods. Thirty adult volunteers provided blood samp…
Phase: NA • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Apr 28, 2026 13:02 UTC
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Blood marker may spot hidden fungus in severe belly infections
Knowledge-focused CompletedThis study looked at whether a substance called β-D-glucan in the blood can help doctors diagnose and monitor fungal infections in the belly (peritonitis). Researchers measured daily levels in 70 intensive care patients with and without yeast infections. The goal was to see if th…
Phase: NA • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Apr 28, 2026 13:02 UTC
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Parvovirus may be linked to thyroid disease, study finds
Knowledge-focused CompletedThis study tested whether a recent parvovirus infection might trigger Graves' disease, an autoimmune thyroid condition. Researchers compared 52 participants—half with newly diagnosed Graves' disease and half with other thyroid issues—looking for parvovirus DNA in their blood. The…
Phase: NA • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Apr 26, 2026 20:02 UTC
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Scientists map facial muscles to perfect smile surgery
Knowledge-focused CompletedThis study aims to better understand how facial muscles move during expressions like smiling. Researchers will use MRI scans and motion-capture cameras to measure muscle and skin movements in 50 healthy adults. The goal is to create a computer model that helps surgeons plan treat…
Phase: NA • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Apr 26, 2026 20:02 UTC
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New method may help heart surgery patients come off blood pressure drugs faster
Knowledge-focused CompletedThis study tested a new method to guide doctors on when to stop giving norepinephrine, a drug that raises blood pressure, to patients who develop dangerously low blood pressure after heart surgery. The method uses a measure called dynamic arterial compliance to decide the right t…
Phase: PHASE3 • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Apr 26, 2026 20:02 UTC
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Pain drug combo studied for safer surgery recovery
Knowledge-focused CompletedThis study looked at how two pain medicines—lidocaine given through a vein and ropivacaine given through an epidural—affect each other's levels in the blood during major abdominal surgery. 51 adults having open abdominal surgery took part. The goal was to see if using both togeth…
Phase: PHASE4 • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Apr 26, 2026 20:02 UTC
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Urine particles may reveal kidney health secrets
Knowledge-focused CompletedThis study looked at tiny particles called extracellular vesicles found in urine to see if they can help tell the difference between healthy kidneys and chronic kidney disease. Researchers measured these particles in 143 adults—some healthy and some with kidney problems. The goal…
Phase: NA • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Apr 26, 2026 20:01 UTC
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AI-Powered heart MRI lets patients breathe easy during scan
Knowledge-focused CompletedThis study tested a new heart MRI technique that uses deep learning to create clear images while patients breathe normally, instead of holding their breath. It included 54 adults with ischemic heart disease. The goal was to see if this method measures heart function as accurately…
Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Apr 26, 2026 20:01 UTC
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MRI may replace painful spinal tap for brain surgery decisions
Knowledge-focused CompletedThis study looked at whether a special MRI scan (flow MRI) can predict if surgery will help people with normal pressure hydrocephalus, a condition where fluid builds up in the brain. Currently, doctors use a spinal tap to test this, but the MRI is non-invasive. The study enrolled…
Phase: EARLY_PHASE1 • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Apr 26, 2026 20:01 UTC
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MRI reveals liver's hidden response to IV fluids in healthy people
Knowledge-focused CompletedThis study looked at how giving a standard amount of fluid through a vein (a fluid challenge) changes blood flow in the liver. 22 healthy volunteers had an MRI before and after receiving 500 ml of salt water. The goal was to see if the liver's blood vessels adjust as expected. Th…
Phase: NA • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Apr 26, 2026 20:00 UTC