Can a phosphate-lowering drug protect kidney patients' bones and heart?

NCT ID NCT01220843

First seen Nov 01, 2025 · Last updated May 12, 2026 · Updated 28 times

Summary

This study tested a drug called sevelamer carbonate in 98 people with chronic kidney disease (stages 3b-4) who were not yet on dialysis. The goal was to see if the drug could lower a blood marker called FGF-23, which is linked to bone and heart problems. Participants took either the drug or a placebo, and researchers measured changes in FGF-23 and other mineral-related substances over time.

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Contacts and locations

Locations

  • CH Valenciennes hémodialyse

    Valenciennes, 59322, France

  • CHU Amiens service de nephrologie

    Amiens, 8000, France

  • CHU Caen service de néphrologie

    Caen, 14033, France

  • CHU Lyon service de néphrologie

    Lyon, 69437, France

  • CHU Marseille Service de néphrologie

    Marseille, 13385, France

  • CHU Reims service de néphrologie

    Reims, 51092, France

  • CHU St Etienne Hopital Nord Service de néphrologie

    Saint-Etienne, 42055, France

  • CHU de Bordeaux Service de néphrologie

    Bordeaux, 33076, France

  • CHU de Montpellier Hôpital Lapeyronie Service de Néphrologie

    Montpellier, 34295, France

  • CHU de Nancy service de néphrologie

    Vandeuvre Les Nancy, 54511, France

  • CHU de Nice Service de néphrologie

    Nice, 06002, France

  • Clinique du Landy Centre de dialyse

    Saint-Ouen, 93400, France

  • Hôpital Européen Georges Pompidou Service de Nephrologie

    Paris, 75098, France

  • Hôpital Tenon Service de Nephrologie

    Paris, 75020, France

  • Néphrologie - Dialyse Centre de Rein Artificiel

    Tassin-la-Demi-Lune, 69160, France

Conditions

Explore the condition pages connected to this study.