Centre Hospitalier Universitaire, Amiens

This study tests whether using a simple urine test to guide the dose of a water pill (furosemide) can safely and effectively remove excess fluid after heart surgery. About 102 adults having heart surgery with a heart-lung machine will be randomly assigned to either standard care …

This study compares two antibiotics, clarithromycin and azithromycin, to treat a lung infection called MAC. About 424 adults with MAC lung disease will receive one of the two drugs, along with other standard medications. The goal is to see if azithromycin works just as well but c…

This study compares a new, faster cardiac MRI that uses artificial intelligence to the standard MRI for measuring heart function in people with left ventricular hypertrophy (thickened heart muscle). The goal is to see if the quicker scan gives equally accurate results while being…

This study is testing whether a blood test measuring a protein called p-Tau217 can accurately diagnose Alzheimer's disease. Currently, diagnosis requires a spinal tap to test spinal fluid, which is invasive and uncomfortable. Researchers will compare the blood test results with t…

This study tests whether using a virtual reality program can help reduce discomfort for patients recovering from major surgery in the intensive care unit (ICU). About 194 adults will be randomly assigned to either receive standard care or standard care plus two short VR sessions …

This study looks at patients with a severe form of shock that combines heart failure with widespread blood vessel relaxation. Researchers will review medical records from 2,500 adults in French hospitals to track survival and organ failure. The goal is to better understand this c…

This study looks at cancer patients who have a blood clot in a vein just under the skin (superficial vein thrombosis). About 15-20% of these clots happen in people with cancer, but there are no clear treatment guidelines. Researchers will observe 1,576 patients to see how differe…

This study looks at how certain immune cells called monocytes might affect how well CART cell therapy works in people with multiple myeloma. Researchers will measure and study monocytes before and after treatment in 25 patients. The goal is to find clues that could help predict w…

This study looks at a protein called annexin A2 on the surface of certain white blood cells (monocytes) in people with antiphospholipid syndrome, a condition that increases the risk of blood clots. Researchers want to see if lower levels of this protein are linked to the disease.…

This study looks at how well two different software programs measure heart function in people with septic shock, a life-threatening condition. Researchers will compare measurements from 60 adult patients to see if the tools give consistent results. The goal is to improve how doct…

This study looks at whether using a special co-sleeping crib (co-dodo) helps breastfeeding mothers and their newborns sleep better and bond more closely in the hospital after birth. About 132 mothers and their babies will be randomly assigned to use either a co-dodo crib or a sta…

This study looks for unknown genetic causes of congenital sideroblastic anemias, a group of rare blood disorders where the body can't use iron properly to make red blood cells. Researchers will analyze DNA from 20 people whose genetic cause is still a mystery. The goal is to find…

This study looks at how pesticides and the natural bacteria in the gut and reproductive organs might be linked to infertility in women with endometriosis. Researchers will compare 160 women with and without endometriosis to measure DNA damage and bacterial patterns. The goal is t…

This study looks at bone marrow stem cells from 50 people with Waldenström macroglobulinemia, a rare blood cancer, and compares them to stem cells from healthy volunteers. Researchers want to understand how these cells interact with cancer cells and influence the disease. The goa…