Could a transplant drug shrink dangerous blood vessel tangles?

NCT ID NCT02042326

First seen May 16, 2026 · Last updated May 16, 2026

Summary

This study tests whether sirolimus, a drug used to prevent organ rejection, can shrink severe arteriovenous malformations (AVMs) and ease symptoms. About 50 people aged 2 and older with advanced AVMs will take sirolimus by mouth for a year. The goal is to see if the drug reduces AVM size and stops it from getting worse, but participants will need ongoing treatment.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Email: •••••@•••••

Locations

  • APHM

    NOT_YET_RECRUITING

    Marseille, 13000, France

    Contact

    Contact Email: •••••@•••••

    Contact

  • APHP

    NOT_YET_RECRUITING

    Paris, 75000, France

  • CHRU Lille

    NOT_YET_RECRUITING

    Lille, 59000, France

  • CHU Amiens

    RECRUITING

    Amiens, 80000, France

    Contact

    Contact

  • CHU Bordeaux

    NOT_YET_RECRUITING

    Bordeaux, 33000, France

  • CHU Dijon

    RECRUITING

    Dijon, 21000, France

    Contact

    Contact

  • CHU Montpellier

    NOT_YET_RECRUITING

    Montpellier, 34000, France

  • CHU Nancy

    NOT_YET_RECRUITING

    Nancy, 54000, France

  • CHU Nice

    NOT_YET_RECRUITING

    Nice, 06000, France

  • CHU Strasbourg

    NOT_YET_RECRUITING

    Strasbourg, 67000, France

  • CHU Tours

    NOT_YET_RECRUITING

    Tours, 37000, France

  • HCL Lyon

    RECRUITING

    Lyon, 69000, France

    Contact

    Contact Email: •••••@•••••

    Contact

    Contact Email: •••••@•••••

  • UCL

    NOT_YET_RECRUITING

    Brussels, Belgium

Conditions

Explore the condition pages connected to this study.