ARTERIOVENOUS MALFORMATIONS
Clinical trials for ARTERIOVENOUS MALFORMATIONS explained in plain language.
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Could a transplant drug shrink dangerous blood vessel tangles?
Disease control Recruiting nowThis study tests whether sirolimus, a drug used to prevent organ rejection, can shrink severe arteriovenous malformations (AVMs) and ease symptoms. About 50 people aged 2 and older with advanced AVMs will take the drug for a year. The goal is to see if the drug reduces AVM size b…
Matched conditions: ARTERIOVENOUS MALFORMATIONS
Phase: PHASE2 • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Disease control
Last updated Jun 27, 2026 12:33 UTC
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New hope for rare vascular malformations: targeted drugs enter trial
Disease control Recruiting nowThis phase 2 trial is testing two targeted drugs—alpelisib and mirdametinib—in 50 people with slow-flow or fast-flow vascular malformations that haven't responded to standard treatments. The goal is to see if these drugs can improve each person's most bothersome symptom over 48 w…
Matched conditions: ARTERIOVENOUS MALFORMATIONS
Phase: PHASE2 • Sponsor: Murdoch Childrens Research Institute • Aim: Disease control
Last updated Jun 27, 2026 12:29 UTC
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Massive study aims to predict brain surgery success
Knowledge-focused Recruiting nowThis study is gathering information from 4500 people who have or will have brain surgery for conditions like aneurysms, tumors, epilepsy, and Parkinson's disease. The goal is to find patterns that help doctors predict how well someone will recover. By standardizing how outcomes a…
Matched conditions: ARTERIOVENOUS MALFORMATIONS
Sponsor: Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:02 UTC
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New study tracks pregnancy dangers in rare vascular conditions
Knowledge-focused Recruiting nowThis study follows 400 pregnant women with rare blood vessel diseases (like HHT, Marfan syndrome, or lymphedema) to learn about serious pregnancy complications. Researchers will ask participants about their health during pregnancy and for 12 months after birth. The goal is to gat…
Matched conditions: ARTERIOVENOUS MALFORMATIONS
Sponsor: Hospices Civils de Lyon • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:01 UTC
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Researchers track Long-Term outcomes after brain AVM treatment
Knowledge-focused Recruiting nowThis study follows 1000 adults who have had embolization for brain arteriovenous malformations (AVMs). The goal is to collect standardized long-term data, such as how well the AVM remains blocked over time. Currently, follow-up practices vary widely, so this research aims to impr…
Matched conditions: ARTERIOVENOUS MALFORMATIONS
Sponsor: Fondation Ophtalmologique Adolphe de Rothschild • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:13 UTC
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Gene hunt: can DNA predict brain bleed risk?
Knowledge-focused Recruiting nowThis study looks at the genes of 300 people with brain or spinal cord arteriovenous malformations (AVMs) to see if certain mutations affect the risk of bleeding. Researchers will compare genetic information with medical outcomes to better understand why some AVMs cause serious pr…
Matched conditions: ARTERIOVENOUS MALFORMATIONS
Sponsor: Fondation Ophtalmologique Adolphe de Rothschild • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:12 UTC