New DNA mapping technique may reveal hidden causes of cleft lip and palate

NCT ID NCT06880094

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study aims to find genetic changes that cause orofacial clefts (like cleft lip and palate) but are missed by standard tests. Researchers will use a new, high-resolution DNA mapping method called optical genome mapping on 26 people with clefts who have no known genetic diagnosis. The goal is to better understand the genetic roots of these common birth defects.

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Conditions

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As listed by the trial registrant

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • CHRU Amiens

    RECRUITING

    Amiens, 80480, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

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