Gene-Guided drug dosing after kidney transplant: a step toward personalized care
NCT ID NCT00552201
First seen Nov 01, 2025 · Last updated May 06, 2026 · Updated 23 times
Summary
This study looked at whether using a patient's genetic information to set the starting dose of tacrolimus (an anti-rejection drug) leads to better drug levels in the blood after a kidney transplant. 280 adults receiving a kidney transplant were randomly assigned to get either a standard dose or a dose based on their CYP3A5 gene. The goal was to see if the gene-based approach helped more patients reach the target drug level faster. The study lasted 3 months per patient.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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CHU Angers
Angers, France
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CHU Gabriel Montpied
Clermont-Ferrand, 63003, France
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CHU Limoges - Hôpital Dupuytren
Limoges, 87042, France
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CHU Poitiers- hôpital Jean Bernard
Poitiers, 86021, France
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CHU Reims - Hôpital Maison Blanche
Reims, 51092, France
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CHU Rennes - Hôpital Pontchaillou
Rennes, 35033, France
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CHU Rouen - Hôpital de Bois-Guillaume
Bois-Guillaume, 76230, France
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CHU Strasbourg - Hospices Civils
Strasbourg, 67091, France
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CHU Tours - Hôpital Bretonneau
Tours, 37044, France
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CHU de la côté de Nacre
Caen, 14033, France
Conditions
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