Which nerve block works best for post-surgery chest pain?

NCT ID NCT04222010

Completed Symptom relief Sponsor: Centre Hospitalier Universitaire, Amiens Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tested three different nerve block techniques to control pain after thoracoscopic (chest) surgery. 155 adults were randomly assigned to receive either a serratus plane block, a paravertebral block, or both together, using the anesthetic ropivacaine. The goal was to find which method provides the best pain relief and could help prevent long-term pain.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Ropivacaine (a local anesthetic)
What this could lead to: If successful, this study could identify the best nerve block technique to reduce pain after chest surgery, leading to faster recovery and less chronic pain.
What could go wrong: This is a completed Phase 3 trial with 155 participants, so results are fairly reliable. However, individual responses to pain relief vary, and the best technique may still not eliminate pain for everyone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ANESTHESIA, LOCAL PAIN, POSTOPERATIVE

Contacts and locations

Locations

CHU Amiens

Amiens, 80054, France

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