Nerve block may replace curare in laparoscopic surgery
NCT ID NCT01628952
First seen Jun 27, 2026 ยท Last updated Jun 27, 2026
Summary
This study compares two ways to relax the abdominal muscles during laparoscopic (keyhole) digestive surgery. One method is a nerve block called TAP block, which numbs the abdominal wall. The other is a standard muscle relaxant drug called curare. The trial involves 60 adults aged 18-75 undergoing laparoscopic surgery. Researchers will measure how well each method relaxes the muscles by checking how much air is needed to inflate the abdomen during surgery.
What this could mean
Our plain-language read of the trial. This is informational only โ not medical advice or a prediction.
- Active substance
- Transversus Abdominis Plane (TAP) block (local anesthetic) and curare (muscle relaxant drug)
- What this could lead to
- If successful, this could show that a nerve block provides adequate muscle relaxation without the side effects of curare, potentially improving recovery after laparoscopic surgery.
- What could go wrong
- This is a small, single-center Phase 4 trial with only 60 participants. The results may not apply to all patients or surgeries, and the nerve block might not work as well as curare in some cases.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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CHU Amiens
Amiens, Picardie, 80054, France