Nerve block may replace curare in laparoscopic surgery

NCT ID NCT01628952

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study compares two ways to relax the abdominal muscles during laparoscopic (keyhole) digestive surgery. One method is a nerve block called TAP block, which numbs the abdominal wall. The other is a standard muscle relaxant drug called curare. The trial involves 60 adults aged 18-75 undergoing laparoscopic surgery. Researchers will measure how well each method relaxes the muscles by checking how much air is needed to inflate the abdomen during surgery.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
Transversus Abdominis Plane (TAP) block (local anesthetic) and curare (muscle relaxant drug)
What this could lead to
If successful, this could show that a nerve block provides adequate muscle relaxation without the side effects of curare, potentially improving recovery after laparoscopic surgery.
What could go wrong
This is a small, single-center Phase 4 trial with only 60 participants. The results may not apply to all patients or surgeries, and the nerve block might not work as well as curare in some cases.

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Sign up to get updates when this study changes or when new studies for THE MAIN OF THIS STUDY IS TO COMPARE THE NERVE BLOCK OF THE MUSCLES OF THE ABDOMINAL WALL BETWEEN THE BILATERAL TAP BLOCK AND CURARE are added.

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Contacts and locations

Locations

  • CHU Amiens

    Amiens, Picardie, 80054, France