INSOMNIA

This study aims to find the best way to help children aged 7-11 with chronic insomnia. Researchers are comparing two versions of a proven talk therapy (CBT-I): one that includes a strict sleep schedule and one that does not. The goal is to see which approach is more effective at …

This study is testing a program called TAILOR that aims to improve sleep in teenagers who are having suicidal thoughts. The goal is to see if helping teens sleep better can reduce their risk of suicide. About 235 teens, aged 11 to 18, with recent insomnia and suicidal thoughts wi…

This study is testing a new way to help people who have been using prescription sleep aids for a long time. It combines a supervised plan to slowly reduce medication with a digital therapy program that teaches better sleep habits. The goal is to see if this combined approach is m…

This study is testing if a special sleep therapy can help women veterans who have both PTSD and insomnia feel more ready to start and stick with PTSD treatment. It will compare a therapy focused on improving sleep habits to a standard educational program. The goal is to see if im…

This study is testing a digital therapy program delivered through a smartphone or computer to help people with insomnia. It aims to see if this accessible, online version of a proven talk therapy can improve sleep, reduce related anxiety and depression, and be cost-effective. The…

This study is testing whether treating insomnia first helps breast cancer survivors lose weight more effectively. Researchers will compare two approaches: one group receives insomnia treatment before weight loss coaching, while the other gets basic sleep education first. The stud…

This study is testing whether a combination of wearable devices (like a headband that measures brain waves and a wrist sensor) and a smartphone app can accurately track a person's sleep stages. Researchers will compare the results from these portable devices to the 'gold standard…

This study tests whether an online sleep improvement program for pregnant women can prevent postpartum depression and stress. Researchers will follow 114 women from early pregnancy until six months after birth, measuring sleep quality, stress hormones, and mental health. The goal…

This study is testing two different school-based programs designed to help teenagers get better sleep. It involves 3,000 students aged 13-19 in Sweden. The goal is to see if improving sleep can prevent future symptoms of depression and anxiety while also boosting school performan…

This study is testing two different telehealth programs to help veterans with mild to moderate traumatic brain injury sleep better. Researchers will compare a structured sleep coaching program (CBT-I) with a mindfulness-based approach (MBTI), both delivered in six video sessions.…

This small pilot study is testing whether a virtual sleep therapy program is practical and helpful for people with liver cirrhosis who struggle with insomnia. Researchers will enroll 10 participants to try a telehealth version of cognitive behavioral therapy for insomnia. The mai…

This study is testing whether a combined behavioral therapy program can help older adults who wake up multiple times at night to urinate and also have trouble sleeping. Researchers will compare this special therapy to a general health education program. The goal is to see if trea…

This study is testing whether combining two treatments can improve sleep for people aged 60+ who have both insomnia and mild memory problems. One treatment is a safe, gentle form of brain stimulation (TMS), and the other is a type of talk therapy for insomnia (CBT-I). Researchers…

This study is testing two different ways to deliver a proven talk therapy for insomnia to people with multiple sclerosis (MS). Researchers want to see if one-on-one video sessions with a therapist work better than a self-guided online program at improving sleep, reducing fatigue,…

This study is comparing two gentle methods to help babies with insomnia sleep better. Researchers are testing a new 'bedtime checking' method, which only involves separation at bedtime, against a more common 'standard checking' method that also addresses night wakings. They want …

This study aims to see how well and safely a newer sleep medication called lemborexant works for people who have both insomnia and a psychiatric disorder. About 121 adult participants with these conditions will take the medication for 8 weeks while researchers track their sleep i…

This study is testing whether a simple, non-invasive earbud device can help adult survivors of childhood leukemia who struggle with insomnia. The device gently stimulates a nerve in the ear. Researchers will see if using it nightly improves sleep quality, reduces stress, and help…

This study is testing whether adding meditation or pain education to a proven sleep therapy program can better reduce pain for adults who have both chronic low back pain and long-term insomnia. Researchers will compare three approaches: the standard sleep therapy alone, sleep the…

This study is testing whether an online program can help Black men who have survived prostate cancer and are struggling with insomnia. It will compare a structured internet therapy program to a simple educational website. The main goal is to see if the online approach is practica…

This study is testing whether hormone replacement therapy (HRT) or cognitive behavioral therapy (CBT) works better to reduce insomnia in women going through perimenopause. Researchers will compare these two treatments against basic sleep hygiene advice in 54 participants. Women w…

This study is testing whether a virtual sleep therapy program can help people with type 1 diabetes who also have insomnia. Researchers want to see if improving sleep leads to better blood sugar control and quality of life. They will compare 15 participants receiving sleep therapy…

This study is testing whether an online education program about healthy sleep habits can help women going through menopause sleep better and feel less depressed. 500 women with poor sleep will be randomly assigned to either receive the sleep education or be in a control group. Re…

This study is testing whether a non-invasive magnetic brain stimulation technique can help people with insomnia sleep better. Researchers will recruit 144 adults with insomnia to receive either real or sham (fake) magnetic pulses to different parts of the brain over two to three …

This study is testing whether a smartphone app can help cancer survivors who have trouble sleeping. The app delivers a proven talk therapy program for insomnia. Researchers will compare 146 participants who use the app right away to others who wait 8 weeks to see if it improves s…

This study is testing a 10-week online therapy program designed specifically for Farsi/Dari-speaking young migrants and refugees. It aims to help reduce symptoms of anxiety, depression, grief, and stress. Participants will be randomly assigned to either receive the therapy immedi…

This study aims to find the best treatment for different types of insomnia. Researchers are comparing a behavioral therapy program (CBT-I) with a low-dose medication (trazodone) in 600 adults with chronic insomnia. The goal is to see which treatment works better for people who sl…

This study is testing a wearable headband called PeakSleep that delivers gentle electrical stimulation to the forehead to help people with insomnia fall asleep faster and sleep more soundly. Over 8 weeks, 100 adults with insomnia will use the device at home before bed and track t…

This study is testing whether a type of talk therapy for insomnia (CBT-I) can help reduce impulsive actions and risky decision-making in young people with sleep problems. Researchers will compare the therapy to a basic sleep education program in about 124 participants aged 12-24.…

This study aims to find the best way to deliver online sleep therapy to cancer survivors struggling with insomnia. Researchers will test two factors: whether therapy works better in individual or group sessions, and whether adding follow-up 'booster' sessions helps. The goal is t…

This study tests whether training primary care doctors in current insomnia treatment guidelines leads to better sleep for their patients. Researchers will compare sleep symptoms in patients whose doctors received this special training against patients whose doctors provide their …

This study is testing two different phone-based programs to see which one better helps people with HIV who also have chronic pain and insomnia. One program focuses on building better sleep habits, while the other teaches mindfulness techniques. Researchers want to see if these pr…

This study is testing whether a brief sleep improvement program can help people with substance use disorders stay longer in their recovery treatment. Researchers will work with 150 adults living in a residential recovery program who also have insomnia. The goal is to see if impro…

This study is testing a new wellness program designed to help adults with cystic fibrosis who struggle with severe fatigue and poor sleep. The program combines virtual coaching sessions with strategies to improve sleep and increase physical activity. Researchers will enroll 80 pa…

This study is testing whether an online mindfulness program can help Black women who have trouble sleeping. Researchers want to see if this approach can reduce insomnia and stress, which are linked to heart and metabolic health problems. The program is delivered by nurses in comm…

This study is testing if a non-drug therapy using gentle pressure on specific points of the ear can help people who have both chronic stomach discomfort (functional dyspepsia) and trouble sleeping. Researchers will enroll 176 participants to see if this approach safely reduces sy…

This study is testing a version of Cognitive Behavioral Therapy (CBT) that has been specially adapted for teenagers with insomnia. Researchers will compare the adapted therapy, delivered in 4-6 virtual sessions, to a waitlist group that receives no initial treatment. The main goa…

This study aims to find out which of three common insomnia treatments works best for women going through perimenopause and menopause. It will compare a prescription sleep medication (daridorexant), an antidepressant often used for sleep (trazodone), and an online behavioral thera…

This study is testing whether a condensed, 5-day group therapy program can help military personnel and veterans who struggle with PTSD, insomnia, and frequent nightmares. It compares a specialized therapy targeting sleep problems to general sleep advice, with both groups also rec…

This small pilot study is testing whether a mindfulness meditation app is a practical and acceptable way to help people with chronic insomnia. Thirty adults will be randomly assigned to use the app with guidance, use it without guidance, or just receive standard sleep tips for fo…

This study is testing whether treating insomnia in people with Crohn's disease can improve their sleep and potentially reduce other symptoms like pain and inflammation. Researchers are recruiting 83 participants with both Crohn's disease and insomnia to receive remote treatment. …

This study is testing if adding brief telehealth coaching helps people complete a 6-week digital program for insomnia. Researchers want to see if the extra support helps people, especially those facing more life challenges, stick with the treatment. They will compare results betw…

This study is testing a 10-week online program designed to improve sleep for adults aged 60+ who have insomnia and are worried about their memory. Researchers want to see if better sleep from the program also helps with anxiety, depression, and thinking skills like memory and foc…

This study is testing whether a smartphone app that teaches parents behavioral sleep techniques can help children with autism who have trouble sleeping. It will also see if the app improves parents' own sleep, stress, and mental health. About 195 families will be randomly assigne…

This study aims to train therapists to provide personalized mental health therapies to cancer patients and their caregivers who are experiencing significant distress, anxiety, depression, or sleep problems. About 100 patients and caregivers in Massachusetts will receive therapy s…

This study is testing if the sleep medication suvorexant can help people who are recovering from opioid addiction and also have insomnia. About 300 participants will be randomly assigned to receive either the real medication or a placebo (inactive pill) for 8 weeks. The main goal…

This study is testing whether special blankets can help young people aged 16-24 who have trouble sleeping. Researchers want to see if using these blankets for 4 weeks improves sleep quality and reduces stress. The goal is to find a safe, easy-to-use alternative to medication or i…

This study is testing if a guided online sleep therapy program can help people with moderate to severe traumatic brain injuries who have insomnia. Researchers will compare the computer program against standard care in 80 participants across Colorado. All study activities, includi…

This study compares two types of talk therapy to help military personnel with sleep problems after a mild brain injury. Researchers want to see which therapy works better for improving sleep and reducing other lingering symptoms like headaches and memory issues. The study involve…

This study is testing whether a smartphone app called SleepUp can help reduce insomnia symptoms. The app delivers a form of talk therapy known as CBT-i, which is a standard treatment for sleep problems. Researchers are comparing the app's effectiveness to traditional video-call t…

This study aims to understand how sleep problems, specifically insomnia, develop in the first year after someone is diagnosed with cancer. Researchers will follow 260 patients who had no sleep issues at diagnosis, checking in regularly to track their sleep quality, pain, mood, an…

This study aims to find out if people with insomnia need a different dose of anesthesia during a digestive endoscopy compared to people who sleep normally. Researchers will compare the total amount of the anesthesia drug rimazolen used in both groups. The goal is to gather knowle…

This study aims to gather safety information on the insomnia medication QUVIVIQ when used during pregnancy. It will follow about 785 women who have insomnia, comparing health outcomes for those who took QUVIVIQ during pregnancy to those who did not. The main goal is to understand…

This study aims to find out if people with insomnia need a different amount of anesthesia medicine during a digestive endoscopy procedure compared to people who sleep normally. Researchers will observe 840 adults undergoing the procedure to measure the drug dosage used and monito…

This study is testing whether a common sleep medication (lemborexant) can reduce certain substances in the blood that are linked to brain diseases like Alzheimer's. Twenty adults with insomnia will take the real medication and a placebo for two weeks each to compare the effects. …

This study aims to find out if people with insomnia need more anesthesia medicine during a common digestive scope procedure compared to people who sleep normally. Researchers will observe over 3,000 adults undergoing the procedure to measure the exact drug amounts used and track …

This study aims to see if brain scans can better predict how well a person will respond to online therapy for depression, social anxiety, or insomnia, compared to just asking them. Researchers will scan the brains of 150 people before they start a 12-week online therapy program. …

This study aims to understand if people with insomnia need different amounts of anesthesia during digestive endoscopy procedures compared to people with normal sleep. Researchers will compare the dosage of the anesthesia drug ciprofol between 840 participants with and without ins…

This study aims to understand why children and teenagers with sleep apnea often struggle to use their prescribed breathing machines (PAP therapy). Researchers will follow 82 kids, aged 8-18, who are starting this treatment to see if having insomnia makes it harder to stick with t…