Can online therapy help MS patients sleep better and protect their brains?

NCT ID NCT06434571

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests two ways of delivering cognitive behavioral therapy for insomnia (CBT-I) to people with multiple sclerosis: one-on-one telehealth sessions or a self-guided web program. Researchers will compare these to usual care to see which improves sleep, reduces fatigue, and enhances quality of life. They will also explore whether better sleep may help protect the brain. The trial enrolls 90 adults aged 18–65 with relapsing-remitting or secondary progressive MS and mild-to-moderate disability.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

cognitive behavioral therapy for insomnia (CBT-I) delivered via telehealth or web-based platform

What this could lead to

If successful, this could provide an effective, accessible treatment for insomnia and fatigue in people with multiple sclerosis, potentially also supporting brain health.

What could go wrong

This is a Phase 2 trial with only 90 participants, so results may not apply to everyone. The exploratory brain protection goal is very early and uncertain.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

insomnia multiple sclerosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of Kansas Medical Center- Sleep, Health and Wellness Laboratory

    RECRUITING

    Kansas City, Kansas, 66160, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••