Earbud device could ease insomnia in childhood cancer survivors

NCT ID NCT07191119

Recruiting now Symptom relief Sponsor: St. Jude Children's Research Hospital Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Aug 14, 2026 · Updated 3 times

Summary

This study tests whether a non-invasive earbud that gently stimulates a nerve in the ear can help adult survivors of childhood leukemia who have trouble sleeping. Forty participants will be randomly assigned to receive either active or sham stimulation nightly for 2 to 8 weeks. The goal is to see if the device is practical and whether it improves sleep, stress, and thinking skills.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: transcutaneous auricular vagus nerve stimulation (tVNS) via a non-invasive earbud device
What this could lead to: If it works, this could point toward a safe, drug-free way to improve sleep and brain function in cancer survivors.
What could go wrong: This is a very early, small pilot study (40 people) testing feasibility, not effectiveness. The sham control may show similar results, and benefits may not be large or lasting.

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Conditions

The condition(s) this trial relates to.

acute lymphoblastic leukemia insomnia Precursor Cell Lymphoblastic Leukemia-Lymphoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ACUTE LYMPHOBLASTIC LEUKEMIA (ALL) INSOMNIA SURVIVOR OF CHILDHOOD CANCER

Contacts and locations

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Study contacts

Contact

Email: •••••@•••••

Locations

St. Jude Children's Research Hospital
RECRUITING

Memphis, Tennessee, 38105, United States

Contact Email: •••••@•••••

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