ACUTE LYMPHOBLASTIC LEUKEMIA (ALL)

This program provides access to a CAR-T cell therapy called tisagenlecleucel (Kymriah) for patients with acute lymphoblastic leukemia or diffuse large B-cell lymphoma when their personalized treatment product doesn't meet the usual manufacturing standards for commercial release. …

This international study aims to improve treatment for children and adolescents whose acute lymphoblastic leukemia (ALL) has returned after initial therapy and is considered high-risk. The trial will test whether adding the drug bortezomib to standard chemotherapy helps more pati…

This study provides access to cord blood units that are not yet FDA-approved for patients who need a transplant for blood cancers or other serious blood/immune disorders. It aims to see how well patients' immune systems recover after receiving these transplants and to monitor for…

This study aims to better understand how CAR-T cell therapy works in patients with specific blood cancers (lymphoma and leukemia) in real-world settings. Researchers will closely monitor how long the modified immune cells last in the body and how well they fight the cancer. They …

This study is collecting information on patient outcomes after receiving a cord blood transplant using Memorial Sloan Kettering's optimized procedure. It aims to see how well this standard transplant approach works for adults with high-risk blood cancers like leukemia, lymphoma, …

This program provides early access to the drug venetoclax for patients with certain blood cancers like leukemia and lymphoma before it is fully approved in their country. It is for patients who have no other suitable treatment options and do not qualify for ongoing clinical trial…

This study is testing whether a gentle, home-based program of laughter and fun yoga can help reduce pain in children receiving chemotherapy for leukemia. Researchers will compare 60 children who do the laughter yoga activities plus their usual care with children who receive usual…

This study is testing whether a simple, non-invasive earbud device can help adult survivors of childhood leukemia who struggle with insomnia. The device gently stimulates a nerve in the ear. Researchers will see if using it nightly improves sleep quality, reduces stress, and help…

This study aims to understand how nerve damage develops in children receiving chemotherapy for leukemia. Researchers will follow 173 children aged 8-17 over several months to track their symptoms and identify what factors might predict worse nerve problems. The goal is to gather …

This study aims to understand why children with cancer in low- and middle-income countries often have worse outcomes than those in wealthier nations. Researchers will look back at the medical records of up to 18,000 young patients (ages 0-21) to measure how often treatment fails …