New hope for kids with aggressive leukemia relapse
NCT ID NCT03590171
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether adding the drug bortezomib to standard chemotherapy helps more children with high-risk relapsed acute lymphoblastic leukemia (ALL) achieve remission. About 250 children under 18 with a first relapse of ALL will be randomly assigned to receive either standard chemo alone or chemo plus bortezomib. The goal is to improve remission rates and long-term survival.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Australian & New Zealand Childhood Hematology & Oncology Group
RECRUITINGClayton, Victoria, 3168, Australia
Contact
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CHU Nice
RECRUITINGNice, France
Contact
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Copenhagen University Hospital (Rigshospitalet)
NOT_YET_RECRUITINGCopenhagen, 2100, Denmark
Contact
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Dpt. SCT and Hematology/Oncology University Wroclaw
RECRUITINGWroclaw, 50354, Poland
Contact
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Hòpital Universitaire des Enfants Reine Fabiola
RECRUITINGBrussels, 1020, Belgium
Contact
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Instituto Português de Oncologia de Lisboa
NOT_YET_RECRUITINGLisbon, Portugal
Contact
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Oslo University Hospital
NOT_YET_RECRUITINGOslo, 0027, Norway
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Ospedale Pediatrico Bambino Gesù
RECRUITINGRoma, 00165, Italy
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Prinses Máxima Centrum, Lundlaan
RECRUITINGUtrecht, Netherlands
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Royal Manchester Children's Hospital
NOT_YET_RECRUITINGManchester, M13 9WL, United Kingdom
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St. Anna Kinderkrebsforschung, CCRI
RECRUITINGVienna, 1090, Austria
Contact
Contact
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Tel Aviv Sourasky Medical Centre
RECRUITINGTel Aviv, 64239, Israel
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Turku University Central Hospital
RECRUITINGTurku, SF-20520, Finland
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University Hospital Motol
RECRUITINGPrague, Czechia
Contact
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University Hospital Stockholm
NOT_YET_RECRUITINGStockholm, 17176, Sweden
Contact