New cord blood transplant recipe aims to beat tough blood cancers
NCT ID NCT05884333
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study tests a standardized, optimized approach to cord blood transplantation for adults with high-risk blood cancers like leukemia and lymphoma. The method includes specific chemotherapy, radiation, and stem cell dosing, followed by careful monitoring. Researchers hope to improve survival and reduce side effects like graft-versus-host disease. About 54 participants will be enrolled at Memorial Sloan Kettering.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Cord blood stem cells (double-unit graft) with conditioning chemotherapy (cyclophosphamide, fludarabine, thiotepa) and total body irradiation
- What this could lead to
- If successful, this could improve survival and reduce complications for adults with high-risk blood cancers who need a cord blood transplant.
- What could go wrong
- This is a small, single-center phase 2 study, so results may not apply broadly. Cord blood transplants carry risks like infection, graft failure, and graft-versus-host disease.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Email: •••••@•••••
Locations
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Memorial Sloan Kettering Cancer Center
RECRUITINGNew York, New York, 10065, United States
Contact Email: •••••@•••••
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