INSOMNIA

This study tests whether a digital sleep program (CBT-I) can prevent depression in pregnant people with insomnia. 456 participants will either use the CBT-I app or receive standard sleep hygiene education. Researchers will track who develops depression through one year after birt…

This Phase 3 study tests whether nightly doses of CBD (75mg or 150mg) can reduce insomnia severity in adults over 8 weeks. Participants take capsules or a placebo, and researchers measure changes in sleep quality using a standard questionnaire and sleep efficiency. The goal is to…

This study tests whether adding personalized feedback to an online sleep program helps university students with insomnia. About 70 students will be split into three groups: standard online therapy, enhanced therapy with feedback, or a waitlist. The goal is to see if the extra fee…

This study looks at whether mirtazapine, a drug often used for depression, can improve appetite in people with advanced cancer who have lost weight and have little desire to eat. About 98 patients will receive either mirtazapine or a placebo for 29 days. Researchers will track ch…

This study looks at whether treating insomnia can help people with Crohn's disease feel better, including reducing pain and inflammation. About 83 adults with mild to moderate Crohn's and insomnia will receive a remote sleep treatment. The main goal is to see if the approach is p…

This study aims to find the best way to deliver cognitive behavioral therapy for insomnia (CBT-I) to cancer survivors who have chronic sleep problems. Researchers are comparing individual vs. group sessions and whether adding booster sessions helps. The goal is to create an effec…

This study tests whether virtual yoga classes can help cancer survivors who have trouble sleeping. About 42 survivors will either take 8 virtual yoga sessions over 4 weeks or continue their usual care. Researchers will measure changes in insomnia and sleep quality to see if the o…

This study tests a wearable device called PeakSleep that uses mild electrical stimulation on the brain to help people with insomnia fall asleep faster and wake up less during the night. About 78 adults with insomnia will wear the device at home and track their sleep with a FitBit…

This study tests whether a digital version of cognitive behavioral therapy for insomnia (CBT-I) can improve sleep and reduce pain in 140 adults with chronic pain and insomnia. Participants will either receive the digital CBT-I program or digital sleep hygiene education. The goal …

This study tests a phone-based sleep therapy for people who have insomnia and drink alcohol in ways that could harm their health. The therapy adapts standard insomnia treatment to also address alcohol-related thoughts and behaviors. Researchers will first refine the approach with…

This study tests whether a 9-week online cognitive behavioral therapy program can improve sleep in people with multiple sclerosis (MS). About 550 participants in Norway will either receive the digital therapy or digital education about insomnia. The main goal is to see if the the…

This study tests whether an app that provides cognitive behavioral therapy for insomnia, enhanced with an AI chatbot, can help young people (ages 18-25) sleep better. Half of the 168 participants will use the app with the chatbot, and the other half will use the same app without …

This study compares two mind-body programs—Mahayana Buddhist Awareness Training and Qigong—to see which helps people aged 50-75 with insomnia sleep better. Participants will practice one of these methods and researchers will measure sleep quality, brain activity, and heart rate c…

This study tests a device called Cereset that plays tones to mirror your brainwaves, aiming to reduce stress, anxiety, insomnia, and depression. About 40 nurses from one hospital unit will use the device. The goal is to see if it improves their well-being and job performance.

This study tests whether a type of talk therapy called Cognitive Behavioral Therapy for Insomnia (CBT-I) can improve sleep and daily functioning in veterans who have both psychosis and insomnia. About 152 veterans are taking part. The goal is to see if better sleep leads to bette…

This phase II study tests whether a computerized cognitive training program can improve sleep and brain health in 240 older adults (65+) with insomnia. Participants will do brain exercises at home for about 36 minutes a day, five days a week, for 36 sessions. The study compares t…

This study tests a new digital app called Stellar Sleep, which provides cognitive behavioral therapy for insomnia (CBT-I) online. It aims to help people with insomnia improve their sleep by using a smartphone or computer, and it can automatically upload sleep data from wearable d…

This study tests whether a short, nurse-led group therapy based on sleep restriction can help people with insomnia. 104 adults with insomnia will either receive the sleep restriction program or standard sleep hygiene advice. The goal is to see if this simpler approach reduces ins…

This study compares two non-drug therapies—mindfulness-based therapy and cognitive-behavioral therapy—for pregnant women who have both insomnia and depression. About 100 women in their second trimester will participate to see which approach better reduces sleep problems and depre…

This study is testing whether special drug-free patches can help relieve acute back, shoulder, or other muscle pain and improve sleep. The patches use a gentle vibration technology instead of medication. 150 adults aged 18-64 will wear either an active patch or a sham (fake) patc…

This study tests a special sound app designed to help pregnant women in their first or second trimester who have trouble sleeping. Thirty women will use the app for two weeks, and researchers will track their sleep quality using diaries and smartwatches. The goal is to see if the…

This study looks at whether acceptance and commitment therapy (ACT) can improve sleep for adults with sickle cell disease. Participants will have weekly video chats with a coach for 8 weeks and wear a wrist device to track sleep. The goal is to see if this approach is practical a…

This study tests whether gentle electrical stimulation to the brain can improve sleep quality and help people with insomnia fall asleep faster. Researchers will compare a personalized stimulation approach to a fixed one and a sham (fake) stimulation. 1000 adults aged 18-75 with i…

This study looks at whether adding cognitive behavioral therapy for insomnia (CBT-I) to standard knee osteoarthritis care (education and exercise) helps reduce pain and improve function. About 128 adults aged 45+ with both knee osteoarthritis and insomnia will be followed for 6 m…

This study was designed to see if cognitive behavioral therapy for insomnia (CBT-I) could help teenagers with ADHD who also have trouble sleeping. It planned to enroll adolescents aged 11-18 with both ADHD and insomnia. However, the trial was withdrawn before any participants wer…

This study tests whether a single evening yoga session can improve sleep and heart health in adults aged 18–40, both those with insomnia and healthy sleepers. Participants will try a moderate-intensity vinyasa yoga session, a gentle yoga session, and a quiet rest period on separa…

This study planned to work with teens to improve a mobile app called Firefly, which uses cognitive behavioral therapy to help with insomnia. The goal was to make the app more engaging for teenagers. However, the study was withdrawn before any participants were enrolled, so no res…

This study uses a 30-40 minute online survey to understand how being on call affects sleep in 1,000 medical trainees (students, residents, fellows). It looks at sleep quality, quantity, and disruption to body rhythms. The goal is to gather knowledge to improve sleep health for he…

This study aims to develop an algorithm that can detect insomnia and measure its severity using data from Withings smart devices (like the ScanWatch or Sleep Analyzer) and questionnaires. Researchers will enroll 17,000 adults who already own these devices. The goal is to create a…

This study follows 1,500 people with long-term pain who are joining rehabilitation programs. Researchers want to understand how insomnia symptoms influence pain, function, and work ability. The goal is to use this knowledge to improve future treatments for chronic pain.

This study looks at how sleep problems like apnea, insomnia, and poor sleep quality are linked to heart disease and diabetes in rural southern areas. About 3,680 adults already in a larger health study will wear sleep trackers and answer questionnaires. The goal is to understand …