Can better sleep ease knee pain? new study tests sleep therapy for osteoarthritis

NCT ID NCT05387473

Ongoing Symptom relief Sponsor: Vrije Universiteit Brussel Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study looks at whether adding cognitive behavioral therapy for insomnia (CBT-I) to standard knee osteoarthritis care (education and exercise) helps reduce pain and improve function. About 128 adults aged 45+ with both knee osteoarthritis and insomnia will be followed for 6 months. The goal is to see if treating sleep problems leads to better outcomes than standard care alone.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: cognitive behavioral therapy for insomnia (CBT-I) combined with exercise therapy and education
What this could lead to: If it works, this could offer a better way to manage knee osteoarthritis pain by treating insomnia alongside standard care.
What could go wrong: This is a relatively small, early-stage study (128 participants) and the added benefit of CBT-I may be modest. Results may not apply to all patients.

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Conditions

The condition(s) this trial relates to.

arthritic joint disease Dyssomnias insomnia osteoarthritis, knee Pain Sleep Disorders, Intrinsic sleep-wake disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

INSOMNIA OSTEOARTHRITIS, KNEE

Contacts and locations

Locations

Department Rehabilitation Science

Leuven, Leuven, 3000, Belgium

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