INSOMNIA
Clinical trials for INSOMNIA explained in plain language.
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Sleep fix could be key to beating breast Cancer's return
Disease control CompletedThis study tested whether a short course of talk therapy for insomnia could help breast cancer survivors take their hormone-blocking medication more consistently. Poor sleep is a common side effect of this essential medication, which can lead people to skip doses and increase the…
Matched conditions: INSOMNIA
Phase: NA • Sponsor: University of Strathclyde • Aim: Disease control
Last updated Apr 01, 2026 14:40 UTC
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Needle and mat help seniors kick pill habit
Disease control CompletedThis study tested whether combining acupuncture and yoga with a doctor's plan could help people aged 65 and older safely reduce their use of common anxiety and sleep medications. Over 12 weeks, 23 participants worked with a nurse to lower their medication dose while also receivin…
Matched conditions: INSOMNIA
Phase: NA • Sponsor: Vanderbilt University Medical Center • Aim: Disease control
Last updated Mar 30, 2026 14:34 UTC
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VA tests new training to curb risky prescriptions for veterans
Disease control CompletedThis study tested two different training programs to help VA doctors and clinics improve how they prescribe medications. It focused on three areas: reducing unnecessary medications for older adults, safely using blood thinners, and offering therapy instead of pills for insomnia. …
Matched conditions: INSOMNIA
Phase: NA • Sponsor: VA Office of Research and Development • Aim: Disease control
Last updated Mar 30, 2026 14:28 UTC
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New therapy aims to wean seniors off risky anxiety pills
Disease control CompletedThis small pilot study tested whether a brief cognitive behavioral therapy program could help older adults safely reduce their long-term use of benzodiazepine medications (like Xanax or Valium) for anxiety and insomnia. Researchers worked with 17 adults aged 55+ who were prescrib…
Matched conditions: INSOMNIA
Phase: NA • Sponsor: Beth Israel Deaconess Medical Center • Aim: Disease control
Last updated Mar 27, 2026 12:39 UTC
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Sleep therapy may shield PTSD hearts
Disease control CompletedThis study investigated whether treating insomnia could reduce the higher risk of heart disease seen in people with PTSD. Researchers enrolled 140 adults with both PTSD and insomnia. They tested if an 8-week sleep therapy program could improve key markers of heart health, like bl…
Matched conditions: INSOMNIA
Phase: NA • Sponsor: Duke University • Aim: Disease control
Last updated Mar 27, 2026 12:39 UTC
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Can better sleep stop Alzheimer's? new study investigates
Prevention CompletedThis study tested whether a 6-week sleep improvement program could help older adults with insomnia think more clearly and potentially slow down brain changes linked to Alzheimer's disease. Researchers enrolled 200 adults aged 60-85 and randomly assigned them to either receive the…
Matched conditions: INSOMNIA
Phase: NA • Sponsor: University of Kansas Medical Center • Aim: Prevention
Last updated Apr 01, 2026 14:42 UTC
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One virtual nurse visit could stop sleepless nights and depression
Prevention CompletedThis study tested whether a single virtual coaching session with a nurse could prevent short-term sleep problems from turning into chronic insomnia and depression. It focused on adults with lower incomes or education levels who were starting to have trouble sleeping. Researchers …
Matched conditions: INSOMNIA
Phase: NA • Sponsor: Henry Ford Health System • Aim: Prevention
Last updated Mar 30, 2026 14:28 UTC
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New hope for sleepless teens? study tests promising pill
Symptom relief CompletedThis study tested whether a medication called daridorexant could help teenagers with chronic insomnia sleep longer and better. It involved 166 participants aged 10 to 17 who had trouble falling or staying asleep at least three nights a week for over three months. Researchers meas…
Matched conditions: INSOMNIA
Phase: PHASE2 • Sponsor: Idorsia Pharmaceuticals Ltd. • Aim: Symptom relief
Last updated Apr 01, 2026 14:43 UTC
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Digital therapy tested to help young refugees cope with trauma and stress
Symptom relief CompletedThis study tested whether an online therapy program, specially adapted for Arabic-speaking refugee and migrant youth, could help reduce symptoms of anxiety, depression, and trauma. The program used internet-based cognitive behavioral therapy (iCBT) over 6-10 weeks. Researchers co…
Matched conditions: INSOMNIA
Phase: NA • Sponsor: Karolinska Institutet • Aim: Symptom relief
Last updated Apr 01, 2026 14:42 UTC
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Could a simple device help you sleep better?
Symptom relief CompletedThis small pilot study tested whether a non-drug device called Bioboosti could help people with insomnia sleep better. Twenty participants used the device at home for two weeks while researchers tracked their sleep quality and daytime sleepiness. The goal was to see if this safe,…
Matched conditions: INSOMNIA
Phase: NA • Sponsor: Brigham and Women's Hospital • Aim: Symptom relief
Last updated Apr 01, 2026 14:42 UTC
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Tailored sleep therapy tested for arab communities
Symptom relief CompletedThis study tested whether adapting a proven sleep therapy (Cognitive Behavioral Therapy for Insomnia) to fit Arab cultural beliefs and practices makes it more effective. Researchers compared two adapted versions of the therapy—one with surface changes and one with deeper cultural…
Matched conditions: INSOMNIA
Phase: NA • Sponsor: Laval University • Aim: Symptom relief
Last updated Apr 01, 2026 14:42 UTC
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Gentle electric brain zaps tested for depression, anxiety, and more
Symptom relief CompletedThis study tested whether a gentle, non-invasive brain stimulation technique called tDCS could help reduce symptoms of several mental health conditions. It involved 320 people with depression, anxiety, OCD, schizophrenia, or insomnia. Researchers measured changes in symptoms, dai…
Matched conditions: INSOMNIA
Phase: NA • Sponsor: Menoufia University • Aim: Symptom relief
Last updated Apr 01, 2026 14:41 UTC
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Sleeping pill from a plant? cannabis oil tested for Depression-Related insomnia
Symptom relief CompletedThis small, completed pilot study explored whether a cannabis-infused oil could help improve sleep for people with major depression who also have chronic insomnia. Fourteen participants were randomly assigned to receive either a placebo or one of two oil formulas with different C…
Matched conditions: INSOMNIA
Phase: PHASE2 • Sponsor: St. Joseph's Healthcare Hamilton • Aim: Symptom relief
Last updated Apr 01, 2026 14:41 UTC
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Can talk therapy help veterans sleep?
Symptom relief CompletedThis study tested two different talk therapies to help Gulf War veterans with insomnia sleep better. Fifty veterans received either Behavioral Therapy, which focuses on setting a consistent sleep schedule, or Cognitive Therapy, which helps change unhelpful thoughts about sleep. R…
Matched conditions: INSOMNIA
Phase: NA • Sponsor: VA Office of Research and Development • Aim: Symptom relief
Last updated Apr 01, 2026 14:41 UTC
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Shining a light on better sleep: can lasers and LEDs calm your nerves?
Symptom relief CompletedThis study tested whether shining low-level laser or LED light on specific pressure points on the hand could help people relax, sleep better, and feel less anxious. Researchers compared the two light sources in 120 participants, measuring changes in heart rate and the body's ener…
Matched conditions: INSOMNIA
Phase: NA • Sponsor: National Yang Ming Chiao Tung University • Aim: Symptom relief
Last updated Mar 31, 2026 12:12 UTC
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Headband hopes to tame midlife sleep woes
Symptom relief CompletedThis study tested whether it was practical for midlife women with sleep problems to use a special headband that senses brain activity. The goal was to see if using this device could help improve their sleep quality. Researchers measured changes in sleep, stress, anxiety, and qual…
Matched conditions: INSOMNIA
Phase: NA • Sponsor: Mayo Clinic • Aim: Symptom relief
Last updated Mar 31, 2026 12:11 UTC
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One online session to help cancer survivors sleep?
Symptom relief CompletedThis study tested whether a single online education session could help cancer survivors with insomnia sleep better. About 70 participants were randomly assigned to either a sleep education program or a relaxation program. Researchers measured changes in sleep quality and mood ove…
Matched conditions: INSOMNIA
Phase: NA • Sponsor: Dana-Farber Cancer Institute • Aim: Symptom relief
Last updated Mar 30, 2026 14:34 UTC
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Can a Plant-Based pill be the answer to your sleepless nights?
Symptom relief CompletedThis study tested whether a daily supplement containing plant protein and two herbs (ashwagandha and rhodiola) could help improve sleep. One hundred middle-aged adults with sleep problems took either the real supplement or a look-alike placebo for 30 days. Researchers measured ch…
Matched conditions: INSOMNIA
Phase: NA • Sponsor: Universidad Pablo de Olavide • Aim: Symptom relief
Last updated Mar 30, 2026 14:33 UTC
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Sleep pill tested for stress and sleepless nights
Symptom relief CompletedThis study tested whether a medication called Neurexan could help people with recent, short-term insomnia sleep better and feel less stressed. For 14 days, 81 adults took either Neurexan or a placebo (inactive pill). Researchers measured sleep patterns in a sleep lab, tracked str…
Matched conditions: INSOMNIA
Phase: PHASE2 • Sponsor: Biologische Heilmittel Heel GmbH • Aim: Symptom relief
Last updated Mar 30, 2026 14:33 UTC
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New hope for restless nights in liver disease?
Symptom relief CompletedThis study tested whether a sleep medicine called lemborexant is safe and effective for people with liver cirrhosis who have trouble sleeping. It involved 82 adults with cirrhosis and poor sleep, comparing the drug to a placebo. The goal was to see if it improved sleep quality wi…
Matched conditions: INSOMNIA
Phase: PHASE2 • Sponsor: Indonesia University • Aim: Symptom relief
Last updated Mar 30, 2026 14:32 UTC
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Could a glass of cherry juice be the key to better sleep?
Symptom relief CompletedThis small pilot study explored whether drinking tart cherry juice could help improve sleep for older adults with insomnia. Twenty participants aged 65+ tried both cherry juice and a placebo drink for four weeks each while wearing a sleep monitor. The main goal was to see if this…
Matched conditions: INSOMNIA
Phase: NA • Sponsor: Courtney Millar • Aim: Symptom relief
Last updated Mar 30, 2026 14:30 UTC
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New pill aims to tame sleepless nights
Symptom relief CompletedThis study tested whether a new drug called tasipimidine helps people with insomnia fall asleep faster and stay asleep longer. Researchers compared it to a placebo (a dummy pill) in 190 adults who had trouble sleeping for at least three months. Participants' sleep was carefully m…
Matched conditions: INSOMNIA
Phase: PHASE2 • Sponsor: Orion Corporation, Orion Pharma • Aim: Symptom relief
Last updated Mar 30, 2026 14:29 UTC
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Digital sleep aid tested for cancer Survivors' insomnia
Symptom relief CompletedThis study tested an online program to help adult survivors of childhood cancer who struggle with insomnia and thinking problems. Over 1,500 participants were randomly assigned to either a 9-week internet-based sleep therapy program or basic sleep education. Researchers measured …
Matched conditions: INSOMNIA
Phase: NA • Sponsor: St. Jude Children's Research Hospital • Aim: Symptom relief
Last updated Mar 30, 2026 14:28 UTC
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Zap to nap? brain stimulation tested for sleepless nights
Symptom relief CompletedThis small, completed study tested whether a personalized form of mild brain stimulation could help people with insomnia sleep better. Twenty participants received the stimulation treatment over two weeks. Researchers measured changes in sleep quality, mood, and side effects to s…
Matched conditions: INSOMNIA
Phase: NA • Sponsor: Shanghai Mental Health Center • Aim: Symptom relief
Last updated Mar 27, 2026 12:40 UTC
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Better sleep, calmer brain? therapy targets root of depression
Symptom relief CompletedThis Stanford study tested whether a proven sleep therapy could reduce symptoms of depression and anxiety. Researchers worked with 51 adults who had both poor sleep and elevated depression/anxiety. They used brain scans to see if the therapy, which teaches better sleep habits, ca…
Matched conditions: INSOMNIA
Phase: NA • Sponsor: Stanford University • Aim: Symptom relief
Last updated Mar 27, 2026 12:40 UTC
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Zap your ear to sleep? new device tested for cancer Patients' insomnia
Symptom relief CompletedThis small study tested whether a non-drug, at-home treatment could help breast cancer patients with insomnia. Twenty participants with stage I-IV breast cancer used a device that delivers gentle electrical stimulation to the ear (called taVNS) nightly for a week. The main goal w…
Matched conditions: INSOMNIA
Phase: NA • Sponsor: University of Alabama at Birmingham • Aim: Symptom relief
Last updated Mar 27, 2026 12:38 UTC
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Can a phone app cure sleepless nights for seniors?
Symptom relief CompletedThis study tested whether a smartphone app delivering brief sleep therapy could help older adults with insomnia. Researchers compared the app, which guides users through sleep restriction techniques, to standard online sleep education. The goal was to see if this convenient digit…
Matched conditions: INSOMNIA
Phase: NA • Sponsor: Woolcock Institute of Medical Research • Aim: Symptom relief
Last updated Mar 27, 2026 12:38 UTC
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Can a single online class cure sleepless nights for young cancer survivors?
Symptom relief CompletedThis study tested whether a single online sleep education session could help young adult cancer survivors who struggle with insomnia. About 56 participants were randomly assigned to receive the education alone or with two extra coaching sessions. Researchers measured changes in s…
Matched conditions: INSOMNIA
Phase: NA • Sponsor: Dana-Farber Cancer Institute • Aim: Symptom relief
Last updated Mar 24, 2026 12:02 UTC
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Can better sleep slow memory loss? new digital therapy tested
Symptom relief CompletedThis study tested whether an online sleep improvement program is practical and acceptable for people with mild memory problems or early-stage dementia who also have trouble sleeping. Researchers enrolled 30 older adults to try the digital program, which teaches techniques to impr…
Matched conditions: INSOMNIA
Phase: NA • Sponsor: University College Cork • Aim: Symptom relief
Last updated Mar 23, 2026 15:19 UTC
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New online tool aims to help parents tackle sleep struggles in kids with autism
Symptom relief CompletedThis study tested an online program designed to help parents improve sleep for their preschool-aged children with autism. Researchers adapted proven sleep strategies into easy-to-access videos and materials that parents could use at home. The goal was to see if this online approa…
Matched conditions: INSOMNIA
Phase: NA • Sponsor: University of California, San Francisco • Aim: Symptom relief
Last updated Mar 23, 2026 15:19 UTC
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New sleep program aims to help veterans with memory issues sleep better
Symptom relief CompletedThis study tested a new sleep therapy program designed for older veterans who have both memory problems and trouble sleeping. The program combines standard sleep therapy with special memory support strategies to help participants follow the treatment better. Researchers wanted to…
Matched conditions: INSOMNIA
Phase: NA • Sponsor: VA Office of Research and Development • Aim: Symptom relief
Last updated Mar 23, 2026 15:17 UTC
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Can a sleep pill sharpen your mind and mood the next day?
Symptom relief CompletedThis study tested whether suvorexant, an FDA-approved sleep medication, improves daytime symptoms like fatigue, mood, and thinking in older adults with chronic insomnia. Forty participants were randomly assigned to receive either the medication or a placebo pill for about two wee…
Matched conditions: INSOMNIA
Phase: PHASE2 • Sponsor: University of Maryland, Baltimore • Aim: Symptom relief
Last updated Mar 23, 2026 15:15 UTC
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Mindfulness vs. sleep coaching: which helps students snooze?
Symptom relief CompletedThis study compared two non-drug programs to help university students with insomnia. One program used mindfulness meditation techniques, while the other used structured cognitive-behavioral therapy (CBT) to change sleep thoughts and habits. Researchers tested 57 students to see w…
Matched conditions: INSOMNIA
Phase: NA • Sponsor: Laval University • Aim: Symptom relief
Last updated Mar 23, 2026 15:14 UTC
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Can a sleep pill fight ICU confusion after heart surgery?
Symptom relief CompletedThis study tested if a prescription sleep medication (suvorexant) could help older patients sleep better and reduce confusion (delirium) after major heart surgery while they were in the intensive care unit (ICU). It involved 100 patients aged 60+ who were randomly given either th…
Matched conditions: INSOMNIA
Phase: PHASE4 • Sponsor: Beth Israel Deaconess Medical Center • Aim: Symptom relief
Last updated Mar 18, 2026 14:42 UTC
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Can a sleep app ease the pain? new study investigates
Symptom relief CompletedThis study tested whether adding a smartphone app that delivers cognitive-behavioral therapy for insomnia (CBT-I) to a standard 4-week inpatient rehabilitation program helps people who have both chronic pain and sleep problems. 105 participants with musculoskeletal pain and insom…
Matched conditions: INSOMNIA
Phase: NA • Sponsor: Norwegian University of Science and Technology • Aim: Symptom relief
Last updated Mar 18, 2026 14:41 UTC
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Can a CBD pill finally help you sleep? new study investigates
Symptom relief CompletedThis study tested whether a capsule containing highly purified CBD and plant compounds called terpenes could improve sleep for people with chronic insomnia. For 12 weeks, 125 participants tried both the CBD capsule and a placebo pill for four weeks each, while their sleep was tra…
Matched conditions: INSOMNIA
Phase: PHASE2 • Sponsor: Defined Research • Aim: Symptom relief
Last updated Mar 16, 2026 15:23 UTC
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Can a phone app ease your back pain by fixing your sleep?
Symptom relief CompletedThis study tested whether a 3-week digital sleep therapy program, delivered through a mobile app called SleepFix, could help reduce how much chronic low back pain interferes with daily life. Researchers compared the app to weekly sleep education emails in 106 adults who had both …
Matched conditions: INSOMNIA
Phase: NA • Sponsor: Woolcock Institute of Medical Research • Aim: Symptom relief
Last updated Mar 13, 2026 15:05 UTC
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Sleep therapy shows promise for rewiring painful brains
Symptom relief CompletedThis study tested whether a non-drug sleep therapy could reduce pain in women with fibromyalgia. Researchers compared two behavioral sleep programs to see if better sleep could change how the brain processes pain signals. The goal was to see if this relatively brief therapy could…
Matched conditions: INSOMNIA
Phase: NA • Sponsor: University of Missouri-Columbia • Aim: Symptom relief
Last updated Mar 12, 2026 13:51 UTC
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Chile's pain puzzle: major study tracks how hurt and stress connect
Knowledge-focused CompletedThis study followed over 2,300 adults in Chile for one year to understand how common chronic pain is and how it connects to mental health, loneliness, and work stress. Researchers called participants to track their pain levels, mood, sleep, and daily life impact over 12 months. T…
Matched conditions: INSOMNIA
Sponsor: Pontificia Universidad Catolica de Chile • Aim: Knowledge-focused
Last updated Mar 31, 2026 12:11 UTC
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Scientists map the Mind's recovery after the heart stops
Knowledge-focused CompletedThis study aimed to understand how a person's thinking, memory, and emotional health are affected after their heart stops (cardiac arrest). Researchers compared 200 survivors of cardiac arrest to people who had a heart attack but did not have their heart stop. They gave detailed …
Matched conditions: INSOMNIA
Sponsor: Region Skane • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:34 UTC
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Scientists track sleep and sugar in cystic fibrosis patients
Knowledge-focused CompletedThis study aimed to understand the connection between blood sugar levels and sleep in adults with cystic fibrosis-related diabetes (CFRD). Thirty participants completed a 10-day home study where their glucose, sleep, and daily activity were monitored remotely. The goal was to gat…
Matched conditions: INSOMNIA
Sponsor: Massachusetts General Hospital • Aim: Knowledge-focused
Last updated Mar 27, 2026 12:41 UTC
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Sleep troubles may worsen pain for HIV patients
Knowledge-focused CompletedThis study aimed to understand how insomnia affects pain sensitivity, physical function, and inflammation in people living with HIV. Researchers followed 171 participants—some with HIV, some without, and some with insomnia—measuring their sleep patterns, pain responses, and blood…
Matched conditions: INSOMNIA
Sponsor: University of Alabama at Birmingham • Aim: Knowledge-focused
Last updated Mar 27, 2026 12:39 UTC
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Can better sleep lower your blood pressure overnight?
Knowledge-focused CompletedThis study aimed to understand why people with both high blood pressure and insomnia have a higher risk of heart disease. Researchers gave 149 adults with these conditions a 6-week talk therapy program designed to improve sleep. They then measured changes in nighttime blood press…
Matched conditions: INSOMNIA
Phase: NA • Sponsor: Duke University • Aim: Knowledge-focused
Last updated Mar 23, 2026 15:18 UTC