INSOMNIA

This study tested a prevention program using nurse-led coaching to stop mild sleep problems from turning into full-blown insomnia and depression. It involved 167 adults with low income or education who were already having trouble sleeping. The approach used a type of talk therapy…

This study tested a medication called Neurexan in 81 adults with short-term insomnia (trouble sleeping for less than 3 months). Participants took Neurexan or a placebo daily for 14 days. Researchers measured sleep quality using overnight brain activity tests and stress levels usi…

This study looked at whether suvorexant, an FDA-approved sleep drug, helps older adults with insomnia feel better during the day. Forty participants took either the drug or a placebo and reported their thinking, mood, and tiredness on a smartphone. The goal was to see if better s…

This study tested whether a daily mix of plant protein and two herbs (ashwagandha and rhodiola) could improve sleep in 100 adults aged 35-70 with sleep problems. Participants took either the active supplement or a placebo for 30 days and reported their sleep quality daily. The go…

This study tested a sleep medication called lemborexant in 82 adults with liver cirrhosis who had trouble sleeping. The goal was to see if the drug could improve sleep quality safely. The approach used a drug that works differently from common sleep aids to avoid liver-related ri…

This study tested whether combining acupuncture, yoga, and doctor-supervised medication tapering helps older adults (65+) reduce their use of benzodiazepines (medications for anxiety and insomnia). 23 participants received weekly treatments for 12 weeks. The goal was to see if th…

This study tested a mobile app called SleepFix that delivers behavioral therapy for insomnia in 106 adults with chronic low back pain and poor sleep. The goal was to see if using the app for 3 weeks could reduce how much pain interferes with daily life after 6 weeks. Participants…

This pilot study tested a brief cognitive behavioral therapy (CBT) program to help older adults (55+) safely reduce their use of benzodiazepines, which are commonly prescribed for insomnia and anxiety but can be risky with age. Seventeen participants worked with therapists to lea…

This study tested whether a headband that senses brain activity (Muse-S) can help midlife women with sleep problems like insomnia. 31 women going through menopause wore the device at home. Researchers measured changes in sleep quality and stress using questionnaires.

This study tested an internet-based sleep program for veterans with both COPD and insomnia. 13 veterans were randomly assigned to either the online sleep treatment or online sleep education. The goal was to see if the program could improve sleep and quality of life. Results were …

This study tested a six-week sleep program in 200 older adults (ages 60-85) with insomnia to see if it improves thinking, memory, and attention. A small group also had brain scans to check if better sleep slows the buildup of a protein linked to Alzheimer's. The goal was to learn…

This study tested whether a sleep improvement program (CBT-I) could reduce depression and anxiety symptoms in 51 adults with sleep problems and mood issues. Participants received six sessions of CBT-I over eight weeks. Researchers used brain scans to see if better sleep changed h…

This study tested a smartphone app that delivers a brief behavioral therapy for insomnia in adults aged 60 and older. 270 participants used either the app or received online sleep health education. The goal was to see if the app could reduce insomnia symptoms and improve sleep qu…

This study tested an internet-based insomnia treatment for adult survivors of childhood cancer who have trouble sleeping. Over 1,500 participants used a program to improve their sleep, and researchers checked if better sleep also helped their thinking and daily life. The goal was…

This pilot study looked at whether cognitive behavioral therapy for insomnia (CBT-I) could help breast cancer survivors take their daily hormone therapy pills more consistently. 35 women who had trouble sleeping and sometimes missed their medication took part. The goal was to see…

This small study tested whether cannabis oil can improve sleep in people with major depression and insomnia. 14 adults took either cannabis oil or a placebo to see if it helped them fall asleep faster and sleep better. The goal was to see if a larger study is possible and if diff…

This early-stage study tested a new insomnia medication called HEC83518 in 57 healthy Chinese adults aged 18 to 45. The main goal was to check if the drug is safe and how the body processes it, including the effect of food. Participants took multiple doses and were monitored for …

This study tested if an app-based sleep therapy could help people with long-term pain and insomnia during a 4-week rehab program. 105 adults took part, with some getting the app therapy plus usual rehab, and others just rehab. The goal was to see if the app improved sleep problem…

This study tested whether shining low-level laser or LED light on specific hand acupoints can help people with insomnia relax and sleep better. 120 participants received either real or sham light therapy, and researchers measured changes in heart rate and energy levels. The goal …

This small study tested a new cognitive training program (COGMUSE) in 12 autistic adults who also have insomnia. Participants played brain-training games at home for 60 minutes, three times a week, for six weeks. The goal was to see if the program was easy to use and could improv…

This pilot study tested a specially adapted sleep therapy program, called Sleep-SMART, for 30 older veterans who have both mild cognitive impairment (MCI) and chronic insomnia. The program combines standard insomnia treatment with memory-support strategies to help veterans learn …

This study tested a non-invasive brain stimulation method called tDCS in 320 adults with depression, schizophrenia, OCD, anxiety, or insomnia. Participants received the stimulation while researchers measured changes in symptoms using standard rating scales. The goal was to see if…

This early-stage study tested a new insomnia drug called HEC83518 in 74 healthy Chinese adults aged 18-45. The main goal was to check safety and side effects, not to measure how well it works. Researchers gave single rising doses to see how the body processes the drug.

This study tested whether a single online educational session could improve sleep in cancer survivors who have trouble sleeping. 70 survivors with significant insomnia took part. Researchers measured changes in insomnia severity and mood after 8 weeks.

This study tested a culturally adapted online therapy (iCBT) for Arabic-speaking refugee and migrant youth aged 15-29 with common mental health problems like anxiety, depression, and insomnia. 125 participants received either the therapy or were placed in a control group. The goa…

This study looked at whether teaching primary care providers about insomnia treatment helps patients sleep better. Researchers compared patients whose doctors received special training to those getting usual care. Participants completed surveys about their sleep, and some had a s…

This study tested whether a guided meditation called yoga nidra is a practical and helpful option for people dealing with both PTSD and insomnia. Sixty adults who had experienced a stressful or traumatic event and had trouble sleeping took part. They were assigned to either a sho…

This study tested whether taking melatonin before bed can reduce pain and improve sleep in people with chronic low back pain and insomnia. 220 adults aged 18-64 with back pain for at least 3 months and sleep issues were randomly assigned to receive melatonin or a placebo pill for…

This study tested a capsule containing highly purified CBD and natural plant compounds (terpenes) to see if it improves sleep in people with chronic insomnia. 125 adults aged 25-70 with long-term sleep problems took the capsule or a placebo. The researchers measured sleep stages …

This study looked at whether a short sleep therapy program (BBTI) helps people with substance use disorders who live in a residential treatment center. 83 participants wore sleep trackers, completed surveys, and did sleep diaries. The goal was to see if improving sleep helps them…

This study tested two sleep medications, trazodone and eszopiclone, in 673 veterans with PTSD-related insomnia. The goal was to see if either drug could improve sleep quality over 12 weeks. Researchers measured changes in insomnia severity using a standard questionnaire.

This study tested whether a digital cognitive behavioral therapy program for insomnia (Sleepio) is practical and helpful for people aged 50+ with mild cognitive impairment or mild dementia who also have sleep problems. Thirty participants were enrolled to see if they would stick …

This study tested whether a medication called solriamfetol, cognitive behavioral therapy for insomnia (CBT-I), or both together can help people with insomnia sleep better and feel less tired during the day. 115 adults with insomnia took part. The goal was to see if staying awake …

This study tested an online sleep program for 20 preschool children with autism who had trouble sleeping. The program taught parents behavioral strategies to improve their child's sleep. Researchers measured changes in sleep habits and quality to see if the program was easy to us…

This study tested whether a noninvasive device that gently stimulates a nerve in the ear (taVNS) could help improve sleep in people with stage I-IV breast cancer. Twenty participants completed the trial, and researchers measured how practical and acceptable the treatment was. The…

This study tested whether a sleep therapy called Cognitive Behavioral Therapy for Insomnia (CBTi) could be adapted for Arab adults. 54 participants were randomly assigned to receive one of two culturally adapted versions of the therapy or to a wait-list. The goal was to see if th…

This pilot study tested a device called Bioboosti to see if it could help people with insomnia sleep better. Twenty adults with insomnia used the device, and researchers measured changes in sleep quality and daytime sleepiness. The goal was to find a non-drug option for improving…

This study tested a cognitive behavioral therapy (CBT) course for insomnia in 73 adults who also have a chronic physical illness like arthritis, heart disease, or cancer. The goal was to see if the therapy could reduce insomnia symptoms and improve sleep. Participants kept sleep …

This study looked at whether Acceptance and Commitment Therapy (ACT) can help adults with insomnia sleep better. 93 people with insomnia were randomly assigned to receive ACT or be placed on a waiting list. The therapy lasted 7 weeks, and participants were followed for up to 6 mo…

This study tested a single online sleep education session, with or without extra coaching, to help young adult cancer survivors (ages 20-39) who have trouble sleeping. 56 survivors joined the program. The goal was to see if the program could reduce insomnia severity and improve m…

This study tested an online program to help cancer patients with insomnia. The program uses a step-by-step approach based on cognitive-behavioral therapy. Researchers wanted to find out which patients need extra help from a professional and what kind of support works best. The st…

This study tested whether the sleep drug suvorexant could reduce insomnia severity and improve metabolic health in 31 midlife women (ages 40-65) who had insomnia and signs of metabolic syndrome. Participants took the medication for 4 weeks. The goal was to see if better sleep cou…

This study tested whether cognitive behavioral therapy (CBT) for insomnia could reduce pain and improve sleep in women with fibromyalgia. 131 women participated, comparing two sleep-focused treatments. The goal was to see if fixing sleep problems can also help with chronic pain a…

This study looked at whether two types of talk therapy—behavioral therapy and cognitive therapy—can help Gulf War veterans who have trouble sleeping. Fifty veterans took part, and their sleep problems were measured using a standard questionnaire. The goal was to find out which th…

This study looked at whether drinking tart cherry juice can improve sleep in older adults with insomnia. Twenty people aged 65 and older drank both cherry juice and a placebo for four weeks each, while wearing a sleep tracker. Researchers also checked blood and urine for sleep-re…

This study tested whether suvorexant, a sleep medication, could improve sleep and reduce delirium (sudden confusion) in older adults recovering from heart surgery in the intensive care unit. About 100 patients aged 60 and older received either suvorexant or a placebo for 7 nights…

This study tested a smartphone app called DOZE that helps young adults (ages 18-25) with chronic pain and sleep problems learn skills to manage their symptoms. The app combines sleep medicine with self-management techniques. Researchers measured how well participants used the app…

This study looked at 57 university students with insomnia and compared two programs: mindfulness-based stress reduction (MBSR) and cognitive-behavioral therapy for insomnia (CBT-I). Participants attended group sessions over 8 weeks. The researchers found that both programs helped…

This study tested a new drug called tasipimidine to see if it helps people with insomnia fall asleep faster and stay asleep longer. 190 adults with insomnia took either the drug or a placebo for 3 nights in a sleep clinic, and some continued for 4 more weeks at home. Researchers …

This study tested a new sleep medication called daridorexant in 166 teenagers aged 10 to 17 with insomnia. The goal was to see if the drug helps them sleep longer and is safe. Participants took the medicine or a placebo, and their sleep was measured in a lab.

This study tested two types of therapy for insomnia in 134 people who were also being treated for alcohol use disorder. The goal was to see if improving sleep could also help reduce drinking. Participants received either a standard insomnia treatment or a therapy that also focuse…

This study tested a personalized brain stimulation technique for 20 adults with insomnia. Participants received model-driven transcranial electrical stimulation over 10 days. The goal was to see if it could improve sleep and reduce insomnia symptoms, with follow-ups at 3 and 6 we…

This study looked at how cardiac arrest affects thinking, memory, emotions, fatigue, and sleep. About 200 survivors were compared to heart attack patients who did not have a cardiac arrest. Researchers used tests and questionnaires at 7 and 24 months after the event to understand…

This study looked at whether treating insomnia could reduce the risk of heart disease in 140 adults aged 40-59 with PTSD. Researchers measured blood pressure, sleep quality, and other heart risk factors before and after insomnia treatment. The goal was to understand the link betw…

This study looked at how blood sugar levels affect sleep in 30 adults with cystic fibrosis-related diabetes (CFRD). Participants wore devices at home for 10 days to track glucose and sleep patterns. The goal was to see if this type of remote monitoring is feasible and to gather d…

This study looked at 149 adults with high blood pressure and insomnia to understand how poor sleep might increase heart disease risk. Researchers used a sleep therapy called CBT-I to see if improving sleep could lower nighttime blood pressure. The goal was to learn more about the…

This study followed over 2,300 adults from urban areas of Chile for one year to learn more about chronic pain and its effects. Researchers looked at how pain relates to depression, anxiety, sleep problems, and work stress. The goal was to better understand the burden of chronic p…

This study looked at 171 people with HIV to see if insomnia makes pain worse and increases inflammation. Researchers measured pain sensitivity, sleep patterns, and blood markers. The goal is to confirm that treating insomnia could help reduce pain and inflammation in people livin…

This study looked at how often insomnia occurs in people hospitalized for psychiatric conditions. Researchers interviewed 427 patients in Switzerland and Germany to find out how many had insomnia and whether factors like age or diagnosis played a role. The goal was simply to gath…

This study looked at how to help busy doctors in VA clinics change their prescribing habits for three common problems: too many risky medications, blood thinner misuse, and overuse of sleep drugs. Researchers tested two different support strategies across 24 clinics. The goal was…