Sleep therapy may rewire brain to fight depression
NCT ID NCT04424407
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether a sleep therapy called CBT-I could reduce depression and anxiety by improving how the brain controls emotions. 51 adults with poor sleep and depression symptoms took part. They met with a psychologist weekly for six weeks to learn better sleep habits. The researchers used brain scans to see if the therapy changed emotion-related brain activity.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Cognitive Behavioral Therapy for Insomnia (CBT-I)
What this could lead to
If it works, this could point toward a drug-free way to ease depression and anxiety by fixing sleep and the brain's emotion control.
What could go wrong
This is a small, early study (51 people) with no control group, so results may not apply broadly. The main goal was to measure brain changes, not prove a treatment works.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Stanford University
Palo Alto, California, 94304, United States