INSOMNIA

This study tests if a digital program for insomnia (dCBT-I) can prevent depression in perimenopausal women with sleep problems. About 230 women will either get the insomnia program or sleep hygiene tips. Researchers will check their mood and sleep every 3 months for 2 years to se…

This study tests a structured sleep hygiene education program for adults with insomnia. Ten participants will learn simple, non-drug techniques to improve their sleep. The goal is to see if this program can reduce insomnia symptoms and improve daytime well-being.

This study tests if a brief, phone-delivered insomnia treatment (BBTI) can improve sleep and thinking in older adults with HIV compared to a mindfulness approach. 214 participants aged 50+ with insomnia will complete 4 weeks of therapy and be followed for a year. The goal is to s…

This study tests whether daridorexant, a sleep medication, can improve insomnia and depression in people with major depressive disorder. 134 adults will receive either the drug or a placebo for three months. Researchers will measure sleep quality and mood changes using questionna…

This study tests whether a special type of acupressure, given at times linked to the body's internal clock, can help older adults in nursing homes sleep better. Eighty people aged 60 and older will receive either real or fake acupressure for four weeks. Researchers will measure s…

This study tests a smartphone app called BELL-001 that plays personalized sounds to help people with insomnia relax and fall asleep. About 114 adults with insomnia will use either the active app or a sham (fake) version for 4 weeks. The goal is to see if the app improves sleep qu…

This study tests whether tai chi can improve sleep quality in adults aged 40 to 69 with mild to moderate chronic insomnia. Sixty participants will be randomly assigned to either a tai chi group or a walking group for six weeks. The goal is to see if tai chi helps people fall asle…

This study aims to see if an 18-day spa program can reduce insomnia severity. About 270 adults will fill out questionnaires about their sleep, fatigue, and well-being before, right after, and two months after their spa treatment. The goal is to scientifically measure whether the …

This study tests whether a gentle, non-needle laser on the ear can improve sleep in women with breast cancer who have insomnia. About 70 women will either get real laser treatment or a fake version to see if it helps with sleep, fatigue, and mood. The treatment involves 10 sessio…

This study tests a special type of acupuncture (dense cranial electroacupuncture plus body acupuncture) in 148 teens aged 15-22 who have mild to moderate anxiety or depression. Participants receive either the real treatment or a sham version twice a week for 8 weeks. Researchers …

This study tests a sleep program called SleepSMART for 150 veterans who have both insomnia and mild cognitive impairment (MCI). The therapy adapts standard sleep counseling with extra memory aids to help veterans learn and stick with the treatment. Researchers will compare SleepS…

This study tests a parent-led telehealth program to help young autistic children (ages 3 to 7) with insomnia sleep better. About 130 children will be randomly assigned to one of two behavioral interventions for 10 weeks. The goal is to see if the structured Sleep Parent Treatment…

This study tests whether a small, home-use electrical device placed on the ear can improve sleep quality, reduce stress, and help academic performance in health sciences students aged 18–35 with poor sleep. Sixty participants will either receive active stimulation or a placebo-li…

This study tests a new way to treat insomnia in older adults using smart devices like lights and sounds, combined with a proven talk therapy (CBT-I). About 180 healthy adults aged 65 and older with sleep problems will use wearable trackers and a smartphone app. The goal is to see…

This study tests whether a non-invasive treatment called remote ischemic conditioning (RIC) can improve sleep and other non-motor symptoms in people with Parkinson's disease. 48 participants with Parkinson's and insomnia will receive either active RIC (using a blood pressure cuff…

This study looks at whether racism-related stress makes it harder for Black adults with insomnia to benefit from cognitive behavioral therapy (CBTi). About 100 Black adults aged 18-65 with insomnia and depressive symptoms will use a digital CBTi program for 6 weeks. Researchers w…

This study tests whether THC (with or without CBD) can improve sleep in people with solid organ cancer who have insomnia. About 69 participants will receive either THC, a THC/CBD mix, or a placebo. The goal is to see if these cannabis-based treatments can ease insomnia symptoms a…

This study tests whether smelling certain essential oils (aromatherapy) can safely improve sleep in elderly women (aged 60+) who have trouble sleeping while in the hospital. 64 participants will receive either real aromatherapy or a placebo, and their sleep quality will be measur…

This pilot study tests a digital behavioral therapy app (SleepFix) with psychologist support for 40 young people aged 16-24 who have insomnia. Participants will either use the app or receive online sleep education. The goal is to see if the app is easy to use and helps improve sl…

This study tests whether a 6-week program of cognitive behavioral therapy for insomnia (CBT-I) can improve sleep and blood sugar control in adults aged 40 and older with type 2 diabetes and chronic insomnia. Thirty participants will be randomly assigned to receive CBT-I or usual …

This study tests whether electroacupuncture (a type of acupuncture with mild electric pulses) can ease a cluster of tough symptoms—pain, fatigue, trouble sleeping, anxiety, depression, and brain fog—in breast cancer survivors who are on hormone therapy. About 228 women will get e…

This study tests a wearable voice-guided therapy for people who have both insomnia and sleep apnea. The treatment uses a smart eye-mask that talks you through steps to improve sleep. Researchers will measure how well it reduces insomnia and helps people stick with their CPAP mach…

This study will test how well common prescription and over-the-counter sleep medications work for adults with chronic insomnia. About 1,200 people will try different medicines like zolpidem, trazodone, melatonin, and diphenhydramine. The goal is to find which ones are most effect…

This small pilot study will test an 8-week group mindfulness program for 30 Chinese parents who care for children with autism or ADHD. The goal is to see if the program reduces stress, anxiety, depression, and insomnia. Participants will attend weekly 1.5-hour sessions and comple…

This study looks at whether a type of talk therapy for insomnia (CBT-I) can also improve metabolic health, like blood sugar and insulin resistance. Twenty adults with insomnia and higher body weight will be randomly assigned to CBT-I or basic sleep tips for 5 weeks. Researchers w…

This study tests whether wearing blue-blocking glasses at night can help teenagers aged 12-18 who have trouble sleeping and are also dealing with mental health issues. The goal is to see if the glasses can help them fall asleep faster and improve their sleep patterns. Forty parti…

This study tests whether an app-based sleep program can improve sleep in new parents who have insomnia. The program uses cognitive behavioral therapy and meditation techniques. About 250 first-time parents with infants aged 4-12 months will participate. The goal is to see if the …

This study tests whether a special 40 Hz flickering light can improve sleep in people with Parkinson's disease who have trouble sleeping. Thirty participants will use either the flickering light or a regular light for 30 minutes each night for a week. The goal is to see if the li…

This study tests whether a traditional Chinese herbal paste (Ning Shen Dan Xiang) combined with donkey-hide gelatin can improve sleep quality in adults with chronic insomnia. Sixty participants will take the paste twice daily for 8 weeks and complete sleep questionnaires. The goa…

This study tests whether a self-guided mobile app for cognitive behavioral therapy for insomnia (CBTI) can improve sleep in 144 active-duty service members. Participants use the app for five weeks, and researchers measure changes in insomnia severity, depression, PTSD symptoms, a…

This study tests whether daridorexant, a recently FDA-approved insomnia drug, can improve sleep quality and daytime alertness in smokers who are trying to quit. Poor sleep is a major reason people relapse during a quit attempt. The study will enroll 44 adult smokers who smoke at …

This pilot study tests whether a headband that plays sounds timed to your brain's alpha waves can improve sleep for people with both depression and insomnia. Twenty-five participants will wear the headband and a sleep tracker for four weeks, alternating between active stimulation…

This study will test a smartphone app called CONEMO to help adults with depression, anxiety, and insomnia. About 12,400 people from primary care clinics in Brazil will use the app to track and improve their symptoms. The goal is to see if the app helps people feel better and redu…

This study tests whether the SleepQ mobile app can help adults with insomnia sleep better. About 80 participants will use the app along with their usual care for 12 weeks, while another group receives usual care alone. The goal is to see if the app reduces insomnia symptoms and i…

This study tests whether simple changes to the bedroom environment and basic sleep tips can improve sleep in older adults (65+) who live alone, have memory concerns, and struggle with insomnia. Over 8 weeks, researchers will visit participants' homes to make agreed-upon adjustmen…

This study looks at whether a special smartwatch can help warfighters who have trouble sleeping due to PTSD, traumatic brain injury, or chronic stress. The watch detects signs of a stressed nervous system during sleep and gives gentle vibrations to calm it. Researchers will track…

This study looks at whether a brief behavioral therapy for insomnia (BBTI) can improve sleep in people who have lost a loved one and now have trouble sleeping. About 58 adults who have been grieving for at least 6 months and have insomnia will take part. They will either receive …

This study tests a two-session, Zoom-based therapy designed for Deaf adults who use American Sign Language. The goal is to change negative beliefs about mental health treatment and encourage people to seek help. Researchers hope this will reduce suicide risk and improve symptoms …

This study tests a new approach for people with severe insomnia that hasn't improved with standard treatments. Participants receive a mild anesthetic to help them sleep, while researchers monitor brain activity to see if it produces natural sleep patterns. The goal is to improve …

This study tests whether a special sleep therapy (CBT-I) delivered over video calls can help adults with ulcerative colitis who also have insomnia. About 20 people will take part in 5 therapy sessions and complete online sleep diaries and questionnaires. The goal is to see if the…

This study tests a type of talking therapy called Cognitive Behavioral Therapy for Insomnia (CBTi) in 770 young people aged 12-24 in Hong Kong who have moderate mental distress and trouble sleeping. Participants will attend six weekly group sessions led by trained youth workers. …

This study tests whether suvorexant, a medication already used for insomnia, can help Veterans with PTSD and sleep problems better process and reduce fear responses. About 40 Veterans will take the drug for 7 nights and undergo fear conditioning and extinction tests. The goal is …

This study tests whether low-dose laser acupuncture can safely improve sleep in 120 adults with major depression and insomnia. Participants will receive 30 laser sessions over six weeks while continuing their usual depression medication. The study compares real laser acupuncture …

This study tests a new insomnia drug, APSTZD, to see if it helps people stay asleep. About 222 adults with chronic insomnia will receive either APSTZD, an active comparator, or a placebo for 6 weeks. The main goal is to measure how much time they spend awake after falling asleep,…

This study looks at whether facial acupuncture, based on traditional Chinese medicine, can help people with insomnia sleep better. Researchers will track sleep quality, anxiety levels, and other symptoms in 82 participants aged 16 to 30. The goal is to see if this approach offers…

This study tests a psychological program designed to improve sleep quality in female university students aged 18 to 25 who have insomnia. The goal is to see if better sleep helps their thinking skills and academic performance. About 35 participants will take part in the program a…

This small study aims to understand what causes insomnia by testing a drug that may calm a brain region called the locus coeruleus during sleep. 15 adults with insomnia will receive either the drug or a placebo in random order. The goal is not to treat insomnia directly, but to s…