Sleep app could stop postpartum depression before it starts

NCT ID NCT05596318

Ongoing Prevention Sponsor: University of California, San Francisco Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a digital sleep program (CBT-I) can prevent depression in pregnant people with insomnia. 456 participants will either use the CBT-I app or receive standard sleep hygiene education. Researchers will track who develops depression through one year after birth.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: digital cognitive behavioral therapy for insomnia (CBT-I) via the Sleepio app
What this could lead to: If it works, this could offer a simple, scalable way to prevent depression during and after pregnancy by treating insomnia early.
What could go wrong: This is a single trial with no phase designation, so results are preliminary. The intervention is digital and may not work for everyone, and participants with current major depression were excluded.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Depression depressive disorder insomnia perinatal asphyxia prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DEPRESSION INSOMNIA

Contacts and locations

Locations

University of California, San Francisco

San Francisco, California, 94118, United States

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Other studies related to the condition(s) this trial covers.