Sleep app could stop postpartum depression before it starts

NCT ID NCT05596318

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a digital sleep program (CBT-I) can prevent depression in pregnant people with insomnia. 456 participants will either use the CBT-I app or receive standard sleep hygiene education. Researchers will track who develops depression through one year after birth.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

digital cognitive behavioral therapy for insomnia (CBT-I) via the Sleepio app

What this could lead to

If it works, this could offer a simple, scalable way to prevent depression during and after pregnancy by treating insomnia early.

What could go wrong

This is a single trial with no phase designation, so results are preliminary. The intervention is digital and may not work for everyone, and participants with current major depression were excluded.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Depression depressive disorder insomnia perinatal asphyxia prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University of California, San Francisco

    San Francisco, California, 94118, United States