Can your sleep length predict the best insomnia cure?
NCT ID NCT06281756
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looks at 600 adults with chronic insomnia to see if those who sleep less than 6 hours respond differently to treatment than those who sleep longer. Participants first receive 8 weeks of cognitive behavioral therapy (CBT-I). If that doesn't help, they are randomly assigned to take either the medication trazodone or a placebo for another 8 weeks. The goal is to improve sleep and lower blood pressure.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
trazodone
What this could lead to
If successful, this could help doctors choose the best insomnia treatment for each patient, potentially reducing high blood pressure risks.
What could go wrong
This is an early-phase study, so results are uncertain. The treatments may not work differently for the two insomnia types, and benefits may not be large.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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National Jewish Health
RECRUITINGDenver, Colorado, 80206-2761, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Penn State University
RECRUITINGHershey, Pennsylvania, 17033, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Pittsburgh
RECRUITINGPittsburgh, Pennsylvania, 15213-3203, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Université Laval
RECRUITINGQuébec, Quebec, G1V 0A6, Canada
Contact Phone: •••-•••-•••• Email: •••••@•••••