Vascular disorder
MONDO:0005385A general term used to describe any disease affecting blood vessels]. It includes vascular abnormalities caused by degenerative, metabolic and inflammatory conditions, embolic diseases, coagulative disorders, and functional disorders such as posteri or reversible encephalopathy syndrome.
Also known as: disease of vasculature, disease or disorder of vasculature, disorder of vasculature, vascular disorder, vasculature disease, vasculature disease or disorder, vasculopathy
10710 clinical trials for this condition and its sub-types, 141 tagged with Vascular disorder itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Vascular disorder
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Arterial disorder 11 trials · 5,320 incl. sub-types
30 sub-types
- Hypertensive disorder 1,265 trials · 2,142 incl. sub-types Sub-types →
- Coronary artery disorder 1,264 trials · 1,406 incl. sub-types Sub-types →
- Aortic disorder 45 trials · 645 incl. sub-types Sub-types →
- Arteriosclerosis disorder 24 trials · 471 incl. sub-types Sub-types →
- Peripheral arterial disease 317 trials Sub-types →
- Pulmonary embolism 203 trials Sub-types →
- Hypotensive disorder 129 trials · 160 incl. sub-types Sub-types →
- Carotid artery disorder 41 trials · 114 incl. sub-types Sub-types →
- Arterial occlusion 40 trials · 109 incl. sub-types Sub-types →
- Arteritis 5 trials · 104 incl. sub-types Sub-types →
- Large artery stroke 95 trials
- Pediatric arterial ischemic stroke 14 trials
- Pulmonary artery disease 12 trials
- Fibromuscular dysplasia 6 trials Sub-types →
- Carotid web 3 trials
- Sneddon syndrome 2 trials
- Celiac trunk compression syndrome 2 trials
- Cervical artery dissection 2 trials Sub-types →
- Vertebral artery insufficiency 2 trials
- Absence of the pulmonary artery 1 trial
- Anterior spinal artery stroke 1 trial
- Aberrant subclavian artery 0 trials
- Anterior spinal artery syndrome 0 trials
- Basilar artery insufficiency 0 trials
- Fibromuscular dysplasia, multifocal 0 trials
- Pulmonary artery choriocarcinoma 0 trials
- Pulmonary artery leiomyosarcoma 0 trials
- Retinal arterial tortuosity 0 trials
- Splenic artery aneurysm 0 trials
- Subclavian artery aneurysm 0 trials
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Neurovascular disorder 5 trials · 4,202 incl. sub-types
29 sub-types
- Cerebrovascular disorder 108 trials · 3,287 incl. sub-types Sub-types →
- Migraine disorder 391 trials · 412 incl. sub-types Sub-types →
- Retinal vascular disorder 9 trials · 324 incl. sub-types Sub-types →
- Intracranial hypertension 51 trials · 97 incl. sub-types Sub-types →
- Central nervous system vasculitis 3 trials · 55 incl. sub-types Sub-types →
- Trigeminal autonomic cephalalgia 8 trials · 27 incl. sub-types Sub-types →
- Choroid plexus cancer 0 trials · 11 incl. sub-types Sub-types →
- Choroid cancer 0 trials · 10 incl. sub-types Sub-types →
- Hemangioblastoma 9 trials · 10 incl. sub-types Sub-types →
- Lymphatic malformation 5 8 trials
- Choroideremia 6 trials Sub-types →
- Ornithine aminotransferase deficiency 4 trials
- Benign choroid plexus neoplasm 0 trials · 2 incl. sub-types Sub-types →
- Cavernous sinus meningioma 2 trials
- Central nervous system hemangioma 0 trials · 2 incl. sub-types Sub-types →
- Hemangioma of retina 0 trials · 1 incl. sub-types Sub-types →
- Retinal ischemia 1 trial
- Norman-Roberts syndrome 0 trials
- Wyburn-Mason syndrome 0 trials
- Benign neoplasm of choroid 0 trials Sub-types →
- Central nervous system angiosarcoma 0 trials
- Choroidal dystrophy, central areolar 2 0 trials
- Choroidal dystrophy, central areolar, 1 0 trials
- Choroidal sclerosis 0 trials Sub-types →
- Eyelid capillary hemangioma 0 trials
- Malignant jugulotympanic paraganglioma 0 trials
- Microcephaly with or without chorioretinopathy, lymphedema, or intellectual disability 0 trials
- Neoplasm of aortic body 0 trials
- Retinal dystrophies primarily involving Bruch's membrane 0 trials Sub-types →
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Ischemic disease 62 trials · 935 incl. sub-types
6 sub-types
- Myocardial ischemia 221 trials · 502 incl. sub-types Sub-types →
- Brain ischemia 55 trials · 281 incl. sub-types Sub-types →
- Limb ischemia 94 trials
- Ischemic bowel disorder 8 trials · 15 incl. sub-types Sub-types →
- Peripheral ischemia 2 trials
- Retinal ischemia 1 trial
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Peripheral vascular disease 57 trials · 432 incl. sub-types
11 sub-types
- Peripheral arterial disease 317 trials Sub-types →
- Telangiectasis 13 trials · 45 incl. sub-types Sub-types →
- Intermittent vascular claudication 33 trials
- Raynaud disease 10 trials
- Erythromelalgia 3 trials · 10 incl. sub-types Sub-types →
- May-Thurner syndrome 8 trials
- Diabetic peripheral angiopathy 5 trials
- Mesenteric vascular occlusion 5 trials
- Priapism 4 trials
- Thromboangiitis obliterans 4 trials
- Livedo reticularis 3 trials
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Ocular vascular disorder 0 trials · 349 incl. sub-types
3 sub-types
- Retinal vascular disorder 9 trials · 324 incl. sub-types Sub-types →
- Optic choroid disorder 6 trials · 26 incl. sub-types Sub-types →
- Conjunctival vascular disorder 0 trials
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Vein disorder 15 trials · 324 incl. sub-types
13 sub-types
- Varicose disease 40 trials · 178 incl. sub-types Sub-types →
- Venous insufficiency 50 trials · 98 incl. sub-types Sub-types →
- Phlebitis 13 trials · 21 incl. sub-types Sub-types →
- Portal vein thrombosis 18 trials
- Central retinal vein occlusion 6 trials · 15 incl. sub-types Sub-types →
- Occlusion of tributary of retinal vein 6 trials
- Cavernous sinus meningioma 2 trials
- Vein of Galen aneurysm 2 trials
- Isolated mesenteric vein thrombosis 0 trials
- Isolated splenic vein thrombosis 0 trials
- Malignant jugulotympanic paraganglioma 0 trials
- Pulmonary vein leiomyosarcoma 0 trials
- Superior vena cava angiosarcoma 0 trials Sub-types →
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Vasculitis 63 trials · 286 incl. sub-types
18 sub-types
- Necrotizing vasculitis 0 trials · 143 incl. sub-types Sub-types →
- Arteritis 5 trials · 104 incl. sub-types Sub-types →
- Central nervous system vasculitis 3 trials · 55 incl. sub-types Sub-types →
- Phlebitis 13 trials · 21 incl. sub-types Sub-types →
- Immune complex mediated vasculitis 0 trials · 18 incl. sub-types Sub-types →
- Hypersensitivity vasculitis 0 trials · 16 incl. sub-types Sub-types →
- Kawasaki disease 15 trials
- Cutaneous vasculitis 4 trials · 5 incl. sub-types Sub-types →
- Deficiency of adenosine deaminase 2 3 trials
- Retinal vasculitis 2 trials
- Aortitis 1 trial
- Choroiditis 0 trials · 1 incl. sub-types Sub-types →
- Livedoid vasculopathy 1 trial
- Secondary vasculitis 0 trials · 1 incl. sub-types Sub-types →
- Shwartzman phenomenon 0 trials
- Autoimmune vasculitis 0 trials Sub-types →
- Lymphangitis 0 trials
- Vasculitis, lymphocytic, nodular 0 trials
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Blood vessel neoplasm 0 trials · 254 incl. sub-types
5 sub-types
- Vascular cancer 1 trial · 150 incl. sub-types Sub-types →
- Benign blood vessel neoplasm 0 trials · 103 incl. sub-types Sub-types →
- Hemangioendothelioma 3 trials · 20 incl. sub-types Sub-types →
- Cavernous sinus meningioma 2 trials
- Neoplasm of aortic body 0 trials
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Vascular insufficiency disorder 1 trial · 244 incl. sub-types
9 sub-types
- Venous insufficiency 50 trials · 98 incl. sub-types Sub-types →
- Tricuspid valve insufficiency 83 trials
- Aortic valve insufficiency 56 trials Sub-types →
- Vertebrobasilar insufficiency 7 trials
- Chronic intestinal vascular insufficiency 4 trials
- Vertebral artery insufficiency 2 trials
- Basilar artery insufficiency 0 trials
- Congenital mitral valve insufficiency 0 trials
- Splenic infarction 0 trials
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Venous thromboembolism 240 trials
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Thrombotic disease 178 trials · 223 incl. sub-types
8 sub-types
- Portal vein thrombosis 18 trials
- Coronary thrombosis 13 trials
- Intracranial thrombosis 12 trials · 13 incl. sub-types Sub-types →
- Heparin-induced thrombocytopenia 5 trials
- Acquired purpura fulminans 0 trials
- Isolated mesenteric vein thrombosis 0 trials
- Isolated splenic vein thrombosis 0 trials
- Marantic endocarditis 0 trials
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Vascular occlusion disorder 27 trials · 182 incl. sub-types
2 sub-types
- Arterial occlusion 40 trials · 109 incl. sub-types Sub-types →
- Retinal vascular occlusion 0 trials · 53 incl. sub-types Sub-types →
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Skin vascular disease 5 trials · 134 incl. sub-types
20 sub-types
- Angioedema 19 trials · 66 incl. sub-types Sub-types →
- Behcet disease 37 trials
- Familial multiple nevi flammei 12 trials
- Chilblain lupus 1 trial · 3 incl. sub-types Sub-types →
- Livedo reticularis 3 trials
- Maffucci syndrome 2 trials
- Sneddon syndrome 2 trials
- Blue rubber bleb nevus 2 trials
- Malignant atrophic papulosis 2 trials
- Pityriasis lichenoides 1 trial Sub-types →
- Bockenheimer syndrome 0 trials
- Cobb syndrome 0 trials
- Wyburn-Mason syndrome 0 trials
- Angioma serpiginosum 0 trials Sub-types →
- Atrophic papulosis 0 trials Sub-types →
- Calciphylaxis cutis 0 trials
- Cutaneous collagenous vasculopathy 0 trials
- Cutis marmorata telangiectatica congenita 0 trials
- Familial cutaneous telangiectasia and oropharyngeal predisposition cancer syndrome 0 trials
- Generalized essential telangiectasia 0 trials
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Hepatic vascular disorder 1 trial · 116 incl. sub-types
11 sub-types
- Portal hypertension 90 trials
- Portal vein thrombosis 18 trials
- Hepatic veno-occlusive disease 6 trials Sub-types →
- Fontan-associated liver disease 5 trials
- Portosinusoidal vascular disease 3 trials Sub-types →
- Budd-Chiari syndrome 1 trial
- Nutmeg liver 1 trial
- Hepatic infarction 0 trials
- Hepatic vein thrombosis 0 trials
- Liver angiosarcoma 0 trials
- Peliosis hepatis 0 trials
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Coronary microvascular disorder 69 trials
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Vascular ectasia 4 trials · 67 incl. sub-types
5 sub-types
- Telangiectasis 13 trials · 45 incl. sub-types Sub-types →
- Familial multiple nevi flammei 12 trials
- Gastric antral vascular ectasia 3 trials
- Lymphangiectasis 3 trials Sub-types →
- Nevus anemicus 0 trials
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Vascular hemostatic disease 62 trials · 63 incl. sub-types
2 sub-types
- Cavernous hemangioma 1 trial Sub-types →
- Shwartzman phenomenon 0 trials
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Lymphatic malformation 17 trials · 55 incl. sub-types
28 sub-types
- Noonan syndrome 21 trials · 24 incl. sub-types Sub-types →
- Lymphatic malformation 5 8 trials
- Anhidrotic ectodermal dysplasia-immunodeficiency-osteopetrosis-lymphedema syndrome 4 trials
- Lymphatic malformation 12 2 trials
- MPI-congenital disorder of glycosylation 1 trial
- Deafness-lymphedema-leukemia syndrome 1 trial
- Dahlberg-Borer-Newcomer syndrome 0 trials
- Hennekam syndrome 0 trials Sub-types →
- Norman-Roberts syndrome 0 trials
- Campomelia, Cumming type 0 trials
- Congenital primary lymphedema of Gordon 0 trials
- Hypotrichosis-lymphedema-telangiectasia syndrome 0 trials
- Hypotrichosis-lymphedema-telangiectasia-renal defect syndrome 0 trials
- Lymphatic malformation 1 0 trials
- Lymphatic malformation 10 0 trials
- Lymphatic malformation 11 0 trials
- Lymphatic malformation 13 0 trials
- Lymphatic malformation 14 0 trials
- Lymphatic malformation 2 0 trials
- Lymphatic malformation 3 0 trials
- Lymphatic malformation 4 0 trials
- Lymphatic malformation 6 0 trials
- Lymphatic malformation 7 0 trials
- Lymphatic malformation 8 0 trials
- Lymphatic malformation 9 0 trials
- Lymphedema-distichiasis syndrome 0 trials
- Microcephaly with or without chorioretinopathy, lymphedema, or intellectual disability 0 trials
- Yellow nail syndrome 0 trials
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Capillary malformation 4 trials · 49 incl. sub-types
6 sub-types
- Hereditary hemorrhagic telangiectasia 34 trials Sub-types →
- Familial multiple nevi flammei 12 trials
- Capillary malformation-arteriovenous malformation syndrome 3 trials Sub-types →
- Angioma serpiginosum 0 trials Sub-types →
- Cutis marmorata telangiectatica congenita 0 trials
- Stork bite 0 trials
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Vascular malformation 32 trials · 34 incl. sub-types
6 sub-types
- Congenital vascular malformation 1 trial · 2 incl. sub-types Sub-types →
- EPHB4-associated vascular malformation spectrum 0 trials Sub-types →
- Cerebral proliferative angiopathy 0 trials
- Fibro-adipose vascular anomaly 0 trials
- Glomuvenous malformation 0 trials
- Splenic venous malformation 0 trials
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Patent ductus arteriosus 28 trials
4 sub-types
- Char syndrome 0 trials
- PDA1 0 trials
- Patent ductus arteriosus 2 0 trials
- Patent ductus arteriosus 3 0 trials
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Cerebral arteriopathy with subcortical infarcts and leukoencephalopathy 16 trials · 19 incl. sub-types
3 sub-types
- Cerebral arteriopathy, autosomal dominant, with subcortical infarcts and leukoencephalopathy, type 1 19 trials
- Cerebral arteriopathy, autosomal dominant, with subcortical infarcts and leukoencephalopathy, type 2 0 trials Sub-types →
- Cerebral arteriopathy, autosomal recessive, with subcortical infarcts and leukoencephalopathy 1 0 trials
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Lymphatic vessel neoplasm 0 trials · 15 incl. sub-types
1 sub-type
- Lymphangioma 5 trials · 15 incl. sub-types Sub-types →
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Familial thoracic aortic aneurysm and aortic dissection 11 trials · 12 incl. sub-types
9 sub-types
- Aortic aneurysm, familial thoracic 1 1 trial
- Aortic aneurysm, familial thoracic 9 1 trial
- Aortic aneurysm, familial thoracic 10 0 trials
- Aortic aneurysm, familial thoracic 12 0 trials
- Aortic aneurysm, familial thoracic 2 0 trials
- Aortic aneurysm, familial thoracic 4 0 trials
- Aortic aneurysm, familial thoracic 6 0 trials
- Aortic aneurysm, familial thoracic 7 0 trials
- Aortic aneurysm, familial thoracic 8 0 trials
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Thoracic outlet syndrome 11 trials
3 sub-types
- Arterial thoracic outlet syndrome 0 trials
- Neurogenic thoracic outlet syndrome 0 trials
- Venous thoracic outlet syndrome 0 trials
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Calciphylaxis 9 trials
2 sub-types
- Calciphylaxis cutis 0 trials
- Visceral calciphylaxis 0 trials
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Arterial calcification of infancy 7 trials
2 sub-types
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2 sub-types
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Loeys-Dietz syndrome 6 trials
6 sub-types
- Loeys-Dietz syndrome 1 0 trials
- Loeys-Dietz syndrome 2 0 trials
- Loeys-Dietz syndrome 4 0 trials
- Loeys-Dietz syndrome 6 0 trials
- Rienhoff syndrome 0 trials
- Aneurysm-osteoarthritis syndrome 0 trials
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Angioosteohypertrophic syndrome 6 trials
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Congenital portosystemic shunt 4 trials
1 sub-type
- Patent ductus venosus 0 trials
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Capillary disorder 0 trials · 4 incl. sub-types
4 sub-types
- Gastric antral vascular ectasia 3 trials
- Capillary leak syndrome 1 trial
- Breast angiomatosis 0 trials
- Capillary lymphangioma 0 trials
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Angiodysplasia 2 trials · 3 incl. sub-types
2 sub-types
- Angiodysplasia of intestine 1 trial
- Angiodysplasia of stomach 0 trials
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2 sub-types
- Moyamoya disease 5 0 trials
- Aortic aneurysm, familial thoracic 6 0 trials
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Superior vena cava syndrome 2 trials
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Arterial tortuosity syndrome 1 trial
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6 sub-types
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Bleeding disorder, vascular-type 0 trials
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Cholesterol embolism 0 trials
2 sub-types
- Atheroembolism of kidney 0 trials
- Blue toe syndrome 0 trials
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Congenital anomaly of hepatic vein 0 trials
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7 sub-types
- Absence of innominate vein 0 trials
- Agenesis of the superior vena cava 0 trials
- Left superior vena cava persisting to left-sided atrium 0 trials
- Persistent left superior vena cava connecting to the left-sided atrium 0 trials
- Primary superior vena cava aneurysm 0 trials
- Right superior vena cava connecting to left-sided atrium 0 trials
- Subaortic course of innominate vein 0 trials
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Congenital renal artery stenosis 0 trials
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Coronary sinus atresia 0 trials
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Coronary sinus stenosis 0 trials
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Fibrocartilaginous embolism 0 trials
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Internal carotid agenesis 0 trials
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Ischemic colitis 0 trials
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Neonatal Marfan syndrome 0 trials
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Pulmonary venoocclusive disease 0 trials
2 sub-types
- Pulmonary venoocclusive disease 1 0 trials
- Pulmonary venoocclusive disease 2 0 trials
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Segmental arterial mediolysis 0 trials
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Vascular disorder of penis 0 trials
Most studied deeper sub-types
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Breakthrough stent aims to fix Hard-to-Treat aortic aneurysms
Disease control Recruiting nowThis study tests a new device called the Zenith Fenestrated+ Endovascular Graft, used with special stents, to repair aortic aneurysms that involve arteries to the kidneys and other organs. About 105 people with large or fast-growing aneurysms will be enrolled. The goal is to see …
Sponsor: Cook Research Incorporated • Aim: Disease control
Last updated Sep 19, 2026 00:00 UTC
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Inhaled drug aims to ease dangerous lung blood pressure in scarred lungs
Disease control Recruiting nowResearchers are testing an inhaled drug called mosliciguat in people who have pulmonary hypertension caused by interstitial lung disease, a condition where lung scarring leads to high blood pressure in the lungs. The phase 3 trial enrolls about 376 participants who receive either…
Phase 3 • Sponsor: Pulmovant, Inc. • Aim: Disease control
Last updated Sep 13, 2026 00:00 UTC
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CT scans could make heart stent surgery safer and faster
Disease control Recruiting nowThis study tests whether using a CT scan to guide heart stent placement is better than the current standard (IVUS ultrasound) for people with hardened, calcified coronary arteries. About 700 adults with evidence of reduced blood flow to the heart will be randomly assigned to one …
Sponsor: Fundación EPIC • Aim: Disease control
Last updated Sep 10, 2026 00:00 UTC
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New combo therapy for lung scarring and high blood pressure under study
Disease control Recruiting nowThis study tests a new inhaled drug, mosliciguat, added to an existing treatment (treprostinil) for people with high blood pressure in the lungs caused by lung scarring. The goal is to see if the combination is safe and tolerable. About 20 adults with this condition will particip…
Phase 2 • Sponsor: Pulmovant, Inc. • Aim: Disease control
Last updated Sep 04, 2026 00:00 UTC
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New drug aims to stop nosebleeds in rare blood vessel disorder
Disease control Recruiting nowThis study tests an experimental drug called ATV-1601 in people with moderate to severe HHT, a condition that causes frequent nosebleeds and anemia. The trial has two parts: first, participants receive either the drug or a placebo to check safety and effectiveness; then, all elig…
Phase 1/2 • Sponsor: Atavistik Bio, Inc • Aim: Disease control
Last updated Sep 03, 2026 00:00 UTC
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Dissolvable magnesium stent could revolutionize heart disease treatment
Disease control Recruiting nowThis study tests a new device called Freesolve, a temporary magnesium scaffold that props open blocked heart arteries and then dissolves over time. About 1,859 people with up to two new blockages will receive either this scaffold or a standard permanent stent. The goal is to see …
Sponsor: Teleflex • Aim: Disease control
Last updated Sep 02, 2026 00:00 UTC
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Gene therapy builds Cancer-Killing cells inside you – no lab needed
Disease control Recruiting nowThis early-stage trial tests a new gene therapy called KLN-1010 for people with multiple myeloma that has come back or stopped responding to treatment. Instead of removing cells and engineering them in a lab, this therapy works inside the body to create special immune cells that …
Phase 1 • Sponsor: Kelonia Therapeutics, Inc. • Aim: Disease control
Last updated Aug 30, 2026 00:00 UTC
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10-Year study tracks stent graft safety in 1,500 aortic patients
Disease control Recruiting nowThis study follows 1,500 people who received a GORE® TAG® stent graft to treat aortic conditions like aneurysms or dissections. Researchers will monitor device performance and patient outcomes for up to 10 years. The goal is to confirm that this minimally invasive procedure remai…
Sponsor: W.L.Gore & Associates • Aim: Disease control
Last updated Aug 21, 2026 00:00 UTC
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New device could ease lung pressure in heart failure patients
Disease control Recruiting nowThis study tests a device that uses radiofrequency energy to treat high blood pressure in the lungs (pulmonary hypertension) in people with heart failure. The goal is to see if it can reduce serious heart events like hospitalizations or death. About 750 adults with stable heart f…
Sponsor: Pulnovo Medical, Inc. • Aim: Disease control
Last updated Aug 20, 2026 00:00 UTC
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Can a stent heal leg ulcers that Won't close?
Disease control Recruiting nowThis study tests whether placing a stent in a blocked pelvic vein can help heal chronic leg ulcers in people with post-thrombotic syndrome, a complication of deep vein thrombosis. Twenty adults with non-healing venous ulcers will receive the stenting procedure plus standard ulcer…
Sponsor: Ain Shams University • Aim: Disease control
Last updated Aug 15, 2026 00:00 UTC
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New device zaps kidney nerves to lower blood pressure in Real-World study
Disease control Recruiting nowThis study is tracking 1,000 patients with high blood pressure who receive the Paradise Ultrasound Renal Denervation treatment. The procedure uses ultrasound energy to calm overactive nerves near the kidneys, which can help lower blood pressure. Researchers are monitoring blood p…
Sponsor: ReCor Medical, Inc. • Aim: Disease control
Last updated Aug 14, 2026 00:00 UTC
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Could a pill shield the brain and kidneys during heart surgery?
Disease control Recruiting nowThis trial tests whether vericiguat, a drug that relaxes blood vessels, can protect the body during heart surgery. About 170 adults scheduled for open-heart surgery will receive either vericiguat or a placebo starting two days before the operation. Researchers will measure blood …
Phase 4 • Sponsor: Vanderbilt University Medical Center • Aim: Disease control
Last updated Aug 08, 2026 00:03 UTC
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Can a tiny mesh device defuse brain aneurysms? a registry investigates
Disease control Recruiting nowThis study is a registry that will follow about 200 people with brain aneurysms who are treated with a flow diverter device (p64, p64 MW, or p48 MW). The goal is to see how safe and effective these devices are in real-world practice across France. Participants will be monitored f…
Sponsor: Phenox GmbH • Aim: Disease control
Last updated Aug 07, 2026 00:00 UTC
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New ultrasound treatment may help seniors control blood pressure
Disease control Recruiting nowThis study looks at how well a device that uses ultrasound to calm kidney nerves can lower blood pressure in people 65 and older whose blood pressure is not well controlled. Researchers will track 1,000 patients over time using electronic health records. The goal is to see if thi…
Sponsor: ReCor Medical, Inc. • Aim: Disease control
Last updated Jul 18, 2026 00:00 UTC
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Tiny implant aims to relieve chest pain when Heart's small vessels fail
Disease control Recruiting nowThis early study tests a device called the A-FLUX Reducer, which is implanted into a vein in the heart to help blood flow. It is for people with chest pain caused by problems in the heart's tiny blood vessels (microvascular dysfunction). The study will enroll 30 adults and focus …
Sponsor: VahatiCor, Inc. • Aim: Disease control
Last updated Jul 17, 2026 00:00 UTC
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Could a simple ear clip tame brain swelling after a stroke?
Disease control Recruiting nowThis study tests whether a non-invasive device that gently stimulates the vagus nerve through the ear can reduce inflammation and brain swelling after a hemorrhagic stroke (intracerebral hemorrhage). The trial enrolls adults with a specific type of brain bleed and compares the ac…
Sponsor: Washington University School of Medicine • Aim: Disease control
Last updated Jul 08, 2026 00:00 UTC
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New shortcut for blood pressure treatment?
Disease control Recruiting nowThis study tests a faster version of a procedure called renal denervation, which uses energy to calm overactive nerves in the kidneys to lower blood pressure. About 130 adults with uncontrolled high blood pressure will receive the quicker procedure. The goal is to see if it works…
Sponsor: Medtronic Vascular • Aim: Disease control
Last updated Jul 02, 2026 00:00 UTC
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New device zaps kidney and liver nerves to tame high blood pressure
Disease control Recruiting nowThis study tests a device that uses radiofrequency energy to disrupt nerve signals in the kidney and liver arteries, aiming to lower blood pressure in people with uncontrolled hypertension. About 175 adults aged 18-80 with high blood pressure despite medication will be enrolled. …
Sponsor: Medtronic Vascular • Aim: Disease control
Last updated Jun 27, 2026 14:02 UTC
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Aspirin after preeclampsia: a simple pill to protect new Moms' hearts?
Disease control Recruiting nowThis study tests whether taking low-dose aspirin for six months after childbirth can help blood vessels heal and lower blood pressure in women who had preeclampsia. About 60 new mothers will receive either aspirin or a placebo. The goal is to see if this simple treatment can redu…
Phase 4 • Sponsor: Malamo Countouris • Aim: Disease control
Last updated Jun 27, 2026 13:02 UTC
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Could a simple neck device help stroke patients survive?
Disease control Recruiting nowThis study is testing a non-invasive device that stimulates the vagus nerve (a major nerve in the neck) to see if it is safe and helpful for people who have had a severe bleeding stroke called aneurysmal subarachnoid hemorrhage. About 25 adults in the intensive care unit will rec…
Sponsor: Massachusetts General Hospital • Aim: Disease control
Last updated Jun 27, 2026 12:33 UTC
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New drug could extend window for treating deadly stroke
Disease control Recruiting nowThis trial is testing a drug called tenecteplase for people with a severe stroke caused by a blockage in the basilar artery at the back of the brain. About 688 participants will receive either tenecteplase or standard care within 24 hours of symptoms starting, followed by a clot-…
Phase 2/3 • Sponsor: University of Melbourne • Aim: Disease control
Last updated Jun 27, 2026 12:29 UTC
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Nerve-zapping procedure for high blood pressure put to the test in medicare patients
Disease control Recruiting nowThis study tracks 1,000 Medicare patients with uncontrolled high blood pressure to see if a procedure called renal denervation (using the Symplicity Spyral device) helps lower blood pressure and prevent heart attacks or strokes over two years. Researchers will compare patients wh…
Sponsor: Medtronic Vascular • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
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New hope for medium vessel stroke? trial tests direct Clot-Busting drug
Disease control Recruiting nowThis study is testing whether giving a clot-busting drug (tenecteplase) directly into the blocked brain artery can improve outcomes for people having a stroke caused by a medium-sized vessel blockage. About 282 participants will be randomly assigned to receive either the intra-ar…
Sponsor: The Second Hospital of Anhui Medical University • Aim: Disease control
Last updated Jun 27, 2026 12:08 UTC
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Wearable BP monitor takes on the cuff in hypertension showdown
Disease control Recruiting nowThis study compares a wearable blood pressure monitor (Aktiia G1) to a traditional arm cuff in adults with uncontrolled high blood pressure. Over 6 months, researchers will see which method leads to better blood pressure control. Participants must have a smartphone and attend two…
Sponsor: Aktiia SA • Aim: Disease control
Last updated Jun 27, 2026 12:06 UTC
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New leg artery scaffold could help thousands with blocked vessels
Disease control Recruiting nowThis study tests a new device called the efemoral vascular scaffold system (EVSS) in 100 people with blocked leg arteries that cause pain or trouble walking. The scaffold is placed inside the artery to hold it open and improve blood flow. Researchers will check if the device is s…
Sponsor: Efemoral Medical, Inc. • Aim: Disease control
Last updated Jun 27, 2026 12:00 UTC
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New Stent-Graft for aortic aneurysm tested in Real-World registry
Disease control Recruiting nowThis registry is tracking the use of the PERCUTEK Tycheseal stent-graft in up to 200 patients with abdominal aortic aneurysms. The goal is to see how well the device works in everyday practice, focusing on successful deployment, freedom from leaks or rupture, and overall safety. …
Sponsor: American Heart of Poland • Aim: Disease control
Last updated Jun 27, 2026 11:04 UTC
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Could viagra prevent strokes in heart pump patients?
Disease control Recruiting nowThis early-phase trial tests whether sildenafil (the drug in Viagra) can reduce blood vessel damage in people with advanced heart failure who have a mechanical heart pump (LVAD). LVADs help patients live longer, but they often cause blood vessel aging that leads to strokes or ble…
Early phase 1 • Sponsor: Montefiore Medical Center • Aim: Disease control
Last updated Jun 27, 2026 08:13 UTC
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Could one blood thinner be safer than two for older heart patients?
Disease control Recruiting nowThis study looks at whether taking just one blood thinner (single antiplatelet therapy) is safer and as effective as taking two (dual antiplatelet therapy) in older adults or those at high risk of bleeding who have had a balloon procedure to open blocked heart arteries. About 576…
Sponsor: Fondazione Ricerca e Innovazione Cardiovascolare ETS • Aim: Disease control
Last updated Jun 27, 2026 08:12 UTC
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Ear zap may cut ICU stays and costs for brain injury patients
Disease control Recruiting nowThis study tests a non-invasive device that gently stimulates a nerve in the ear to help patients with serious brain or spinal cord injuries recover in the intensive care unit. Researchers want to see if it reduces complications like infections, the need for a breathing tube, and…
Sponsor: Washington University School of Medicine • Aim: Disease control
Last updated Jun 27, 2026 07:55 UTC
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Stem cells injected into hands aim to heal stubborn scleroderma ulcers
Disease control Recruiting nowThis early-phase trial tests whether injecting stem cells (mesenchymal stromal cells) into the hand and forearm muscles can safely help heal painful finger ulcers in people with scleroderma. The study includes 20 participants whose ulcers have not improved with standard treatment…
Phase 1/2 • Sponsor: UMC Utrecht • Aim: Disease control
Last updated Jun 26, 2026 15:33 UTC
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Could a blood pressure cuff boost brain recovery after aneurysm surgery?
Disease control Recruiting nowThis study tests whether a non-invasive treatment called remote ischemic conditioning (RIC) can help people recover after surgery for a ruptured brain aneurysm. RIC involves using a blood pressure cuff on the leg to create brief, harmless blood flow interruptions, which may trigg…
Sponsor: Beijing Tiantan Hospital • Aim: Disease control
Last updated Jun 26, 2026 15:12 UTC
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Could your smartphone detect a heart attack? new study aims to find out.
Diagnosis Recruiting nowThis study is testing a new smartphone-connected 12-lead ECG device to see if it can accurately diagnose heart attacks (STEMI and NSTEMI) in people with chest pain. Researchers will compare the smartphone ECG readings to standard hospital ECGs in 1000 adults. The goal is to valid…
Sponsor: AliveCor • Aim: Diagnosis
Last updated Jun 27, 2026 12:06 UTC
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Ambulance EEG could cut stroke treatment delays by an hour
Diagnosis Recruiting nowThis study tests a portable EEG device called StrokePointer that ambulance crews can use to detect severe strokes caused by large vessel blockages. Currently, over half of these patients are taken to hospitals that cannot perform the needed clot-removal procedure, causing an aver…
Sponsor: Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) • Aim: Diagnosis
Last updated Jun 27, 2026 07:53 UTC
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Stitch showdown: which suture keeps groin wounds safer?
Symptom relief Recruiting nowThis study tests two different stitch materials (PDS and Vicryl) for closing groin incisions after planned vascular surgery. About 259 adults will be randomly assigned to one stitch type or the other. The goal is to see which material leads to fewer wound problems.
Sponsor: The Cleveland Clinic • Aim: Symptom relief
Last updated Jun 27, 2026 13:00 UTC
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Spinal zap may soothe diabetic leg pain and boost circulation
Symptom relief Recruiting nowThis study tests whether a spinal cord stimulator—a device that sends mild electrical pulses to the spine—can reduce pain and improve blood flow in the legs of people with type 2 diabetes who have nerve pain. Researchers will enroll 25 adults with painful diabetic neuropathy and …
Sponsor: University of Chicago • Aim: Symptom relief
Last updated Jun 27, 2026 09:02 UTC
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New antibody shot could trap nicotine in smokers
Symptom relief Recruiting nowThis early-stage study tests a new drug called ATI-1013 in 15 healthy smokers. The drug is an antibody designed to bind to nicotine in the body. The main goal is to check safety and see how long the drug stays in the system. Participants get one IV dose of the drug or a placebo a…
Phase 1 • Sponsor: Antidote Therapeutics, Inc • Aim: Symptom relief
Last updated Jun 27, 2026 07:54 UTC
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Massive study aims to unlock secrets of rare vascular diseases
Knowledge-focused Recruiting nowThis study is collecting medical data and biological samples from people with genetic conditions affecting the heart and blood vessels, their relatives, and healthy volunteers. The goal is to better understand these diseases, improve diagnosis, and lay the groundwork for future t…
Sponsor: National Heart, Lung, and Blood Institute (NHLBI) • Aim: Knowledge-focused
Last updated Sep 20, 2026 00:00 UTC
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Can your education and background protect your brain after a stroke?
Knowledge-focused Recruiting nowThis study looks at how social and lifestyle factors—like education, race, and income—affect a person's thinking and memory after a stroke. Researchers will interview 450 adults who had a stroke and review their brain scans and medical records. The goal is to understand why some …
Sponsor: National Institute of Neurological Disorders and Stroke (NINDS) • Aim: Knowledge-focused
Last updated Sep 19, 2026 00:00 UTC
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Massive heart surgery study aims to uncover hidden risks
Knowledge-focused Recruiting nowThis study is reviewing medical records from 5,000 heart and blood vessel surgery patients to find factors that influence recovery and survival. Researchers are looking at data from 2001 to 2013 to identify what leads to complications or death after surgery. The goal is to improv…
Sponsor: University of California, Davis • Aim: Knowledge-focused
Last updated Sep 16, 2026 00:00 UTC
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Can special heart checkups protect cancer patients from their own treatment?
Knowledge-focused Recruiting nowSome cancer drugs cause rare but serious heart and metabolic problems. This study follows 5,000 cancer patients across several French hospitals who receive a dedicated heart checkup and ongoing follow-up through cardio-oncology programs. Researchers track how many patients benefi…
Sponsor: Groupe Hospitalier Pitie-Salpetriere • Aim: Knowledge-focused
Last updated Sep 13, 2026 00:00 UTC
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Massive study aims to unravel mysteries of blood clots and vessel disease
Knowledge-focused Recruiting nowThis study aims to learn more about how diseases related to blood clots, the immune system, and blood vessels start and change over time. Researchers will enroll up to 1,000 people aged 5 and older, including those with these conditions, their healthy relatives, and healthy volun…
Sponsor: National Heart, Lung, and Blood Institute (NHLBI) • Aim: Knowledge-focused
Last updated Sep 12, 2026 00:00 UTC
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Major stroke study aims to unlock secrets of brain attacks
Knowledge-focused Recruiting nowThis study is for adults 18 and older who have had a stroke or a transient ischemic attack (TIA), often called a mini-stroke. The goal is to collect information from standard medical tests and some extra research tests, like blood draws and brain scans, to better understand how t…
Sponsor: National Institute of Neurological Disorders and Stroke (NINDS) • Aim: Knowledge-focused
Last updated Aug 29, 2026 00:00 UTC
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Liver cirrhosis patients get tested on common blood thinners
Knowledge-focused Recruiting nowThis early-stage study looks at how two common blood thinners, rivaroxaban and apixaban, behave in people with compensated liver cirrhosis. 24 participants receive a single dose of one drug, and researchers measure drug levels and blood clotting markers over 12 hours. The goal is…
Phase 1 • Sponsor: Insel Gruppe AG, University Hospital Bern • Aim: Knowledge-focused
Last updated Aug 21, 2026 00:00 UTC
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New device for leg clots tested in first human survey
Knowledge-focused Recruiting nowThis study surveys doctors who use the Liberant system to remove fresh blood clots from leg arteries and veins. About 50 patients aged 22 or older will be treated within 72 hours of their procedure. The goal is to confirm the device is safe and works as intended.
Sponsor: Medtronic Endovascular • Aim: Knowledge-focused
Last updated Aug 13, 2026 00:00 UTC
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Can 4D-MRI spot brain aneurysms before they rupture?
Knowledge-focused Recruiting nowThis study is testing whether a special MRI technique, called 4D Flow MRI, can better detect and predict the growth of unruptured brain aneurysms. Researchers will follow adults with these aneurysms, using the advanced imaging to measure changes in the aneurysm's shape over time.…
Sponsor: CHU de Reims • Aim: Knowledge-focused
Last updated Aug 09, 2026 00:00 UTC
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Sleep and seizures: new study probes why stroke triggers epilepsy in some patients
Knowledge-focused Recruiting nowThis observational study investigates why some people develop epilepsy after a stroke, while others do not. Researchers will compare first-time stroke patients with healthy volunteers using brain imaging (MRI), electrical brain recordings (EEG), and overnight sleep studies. The g…
Sponsor: Norwegian University of Science and Technology • Aim: Knowledge-focused
Last updated Jul 09, 2026 00:00 UTC
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3D ultrasound could help patients see and understand their vascular disease
Knowledge-focused Recruiting nowThis study is testing whether a new 3D ultrasound system can help people with blood vessel disease better understand their condition. Researchers will give 270 patients a 3D image of their blocked or narrowed vessels instead of the usual hand-drawn sketch. They want to see if thi…
Sponsor: Northwell Health • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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Video link in ambulance could speed up stroke care
Knowledge-focused Recruiting nowThis study tests whether a live video call between a neurologist and emergency medical technicians (EMTs) can improve the accuracy of stroke detection in the ambulance. About 512 adults with suspected stroke will take part. The goal is to see if video assistance helps diagnose st…
Sponsor: University of Southern Denmark • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:33 UTC
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New CT scans reveal Statins' secret effect on heart plaque
Knowledge-focused Recruiting nowThis study looks at how a short course of high-dose statins affects fatty buildup (plaque) in the heart arteries of people with mild heart disease. Researchers will use advanced CT scans to measure changes in plaque size and type over 3 months, and then check if those changes las…
Sponsor: Prof. Maurovich-Horvat Pál • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:33 UTC
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Tiny nerve zap could reveal secrets of blood pressure control
Knowledge-focused Recruiting nowThis study is testing a new way to understand how nerves in the kidney affect blood pressure. About 19 adults with high blood pressure will receive mild electrical stimulation to kidney nerves before and after a procedure that quiets those nerves. The goal is to learn how the bod…
Sponsor: Medtronic Vascular • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC
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Biobank study aims to uncover hidden changes in dialysis Patients' abdominal tissue
Knowledge-focused Recruiting nowThis study collects small tissue samples from the abdomen of children and adults undergoing peritoneal dialysis (a type of kidney treatment). The goal is to learn how the lining of the belly changes over time with dialysis. Researchers will also take samples from healthy people h…
Sponsor: Heidelberg University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:25 UTC
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Why do some moms develop high blood pressure years later? oxford study seeks answers
Knowledge-focused Recruiting nowThis study from the University of Oxford looks at why women who had high blood pressure during pregnancy are more likely to develop heart and blood vessel disease later in life. Researchers will follow 200 women who gave birth 10 to 25 years ago, using heart scans, exercise tests…
Sponsor: University of Oxford • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:24 UTC
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Could a deep clean for your gums also protect your heart?
Knowledge-focused Recruiting nowThis study looks at how standard gum disease treatments—deep cleaning with or without a special mouthwash—change proteins in your saliva and affect blood vessel health. Researchers will study 30 adults with gum disease to see if these treatments help or harm the good bacteria tha…
Sponsor: Mahdi Mutahar • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC
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New scan could spot hidden stroke risk in blocked arteries
Knowledge-focused Recruiting nowThis study is testing whether a new type of PET-MR scan can help predict stroke risk in people with significant narrowing of the carotid artery (the main artery in the neck) who have not yet had symptoms. Researchers will give participants an injection of a radioactive tracer and…
Sponsor: Washington University School of Medicine • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC
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Road map or ultrasound? small study tests safer leg artery punctures
Knowledge-focused Recruiting nowThis study compares two techniques for guiding a needle into a blocked leg artery from the opposite direction (retrograde). One uses a live X-ray map, the other uses ultrasound. Researchers want to see which is safer and more successful in 32 people with severe leg artery disease…
Sponsor: Sohag University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:08 UTC
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Beef on the menu: could a daily serving boost heart health in older adults?
Knowledge-focused Recruiting nowThis study looks at whether eating beef every day as part of a heart-healthy diet helps older adults (ages 55-70) absorb zinc better and improves how their blood vessels work. Researchers will measure zinc levels in cells and blood vessel function in 20 participants. The goal is …
Sponsor: University of California, Davis • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:03 UTC
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Wine's secret signals: study probes how a glass affects aging cells
Knowledge-focused Recruiting nowThis study looks at how moderate wine consumption changes tiny particles called extracellular vesicles, which help cells communicate. Eight healthy adults aged 35-65 will drink red wine, white wine, or water, and researchers will analyze their blood for changes in these particles…
Sponsor: University of Seville • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:13 UTC
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Scientists probe vessel proteins in preeclampsia
Knowledge-focused Recruiting nowThis study collects tissue samples from women with and without preeclampsia during C-sections to examine blood vessel function. Researchers focus on a protein called AT2R, which may play a role in the condition. The goal is to better understand how preeclampsia affects blood vess…
Sponsor: University of Wisconsin, Madison • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:12 UTC
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New study aims to solve the mystery of 'breakthrough' strokes in heart patients
Knowledge-focused Recruiting nowThis study will follow 500 people who have had a stroke and also have atrial fibrillation (an irregular heartbeat). Some were taking blood thinners when they had their stroke, others were not. Researchers want to understand why blood thinners fail in some patients, by looking at …
Sponsor: Insel Gruppe AG, University Hospital Bern • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:59 UTC
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Can exercise rewire your genes to fix blood vessels?
Knowledge-focused Recruiting nowThis study looks at how 12 weeks of aerobic exercise changes DNA methylation—a chemical tag on genes—in fat tissue of 80 people with obesity who are scheduled for bariatric surgery. Researchers want to see if these changes improve blood vessel function and reduce inflammation. Th…
Sponsor: University of Illinois at Chicago • Aim: Knowledge-focused
Last updated Jun 26, 2026 16:58 UTC