Stem cells injected into hands aim to heal stubborn scleroderma ulcers

NCT ID NCT03211793

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This early-phase trial tests whether injecting stem cells (mesenchymal stromal cells) into the hand and forearm muscles can safely help heal painful finger ulcers in people with scleroderma. The study includes 20 participants whose ulcers have not improved with standard treatments. The main goal is to check for side effects, but researchers will also look for signs of better blood flow and ulcer healing.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

mesenchymal stromal cells (stem cells)

What this could lead to

If it works, this could offer a new way to heal stubborn finger ulcers in people with scleroderma, reducing pain and preventing tissue loss.

What could go wrong

This is a very early, small trial (20 people) focused on safety first. It may not show clear benefit, and there are risks like injection-site reactions or worsening ulcers.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

diffuse scleroderma digital ulcers systemic sclerosis vascular disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Universitair Medisch Centrum Utrecht

    RECRUITING

    Utrecht, 3584 CX, Netherlands

    Contact

    Contact

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