Loeys-Dietz syndrome
MONDO:0018954Loeys-Dietz syndrome is a rare genetic connective tissue disorder characterized by a broad spectrum of craniofacial, vascular and skeletal manifestations with four genetic subtypes described forming a clinical continuum.
Also known as: Loeys-Dietz syndrome, aortic aneurysm syndrome due to TGF-beta receptors anomalies, aortic aneurysm syndrome, Loeys-Dietz type
6 clinical trials for this condition and its sub-types.
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Broader categories
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Custom stent grafts offer new hope for High-Risk aneurysm patients
Disease control Recruiting nowThis study is testing whether custom-made or physician-modified stent grafts can safely repair complex aortic aneurysms in people who cannot use standard devices or undergo open surgery. The grafts are tailored to each patient's anatomy, with small holes to keep blood flowing to …
Phase: NA • Sponsor: Andres Schanzer • Aim: Disease control
Last updated Jun 27, 2026 07:55 UTC
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New registry aims to unlock mysteries of Pregnancy-Related aortic tears
Knowledge-focused Recruiting nowThis study is a national registry in China that will track 500 women who experience an aortic dissection (a tear in the main artery) during pregnancy or within 12 weeks after giving birth. Researchers will collect information on treatments and outcomes for both mothers and babies…
Sponsor: DeltaHealth Hospital · Shanghai • Aim: Knowledge-focused
Last updated Jul 19, 2026 00:00 UTC
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Massive study aims to unlock secrets of food allergies
Knowledge-focused Recruiting nowThis study looks at the causes and effects of food allergies and related conditions like eczema and eosinophilic esophagitis. Researchers will collect blood, skin, and genetic samples from up to 1,800 people over many years. The goal is to find biomarkers and pathways that explai…
Sponsor: National Institute of Allergy and Infectious Diseases (NIAID) • Aim: Knowledge-focused
Last updated Jul 03, 2026 00:00 UTC
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Brazil launches massive heart gene hunt to unlock hereditary mysteries
Knowledge-focused Recruiting nowThis study is building a registry of 1,211 people in Brazil who have inherited heart conditions like cardiomyopathy, arrhythmias, and Marfan syndrome. Researchers will collect DNA samples and medical information to discover which genes are most commonly affected and how often the…
Sponsor: Hospital do Coracao • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:30 UTC