Brazil launches massive heart gene hunt to unlock hereditary mysteries

NCT ID NCT06546137

Recruiting now Knowledge-focused Sponsor: Hospital do Coracao Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is building a registry of 1,211 people in Brazil who have inherited heart conditions like cardiomyopathy, arrhythmias, and Marfan syndrome. Researchers will collect DNA samples and medical information to discover which genes are most commonly affected and how often these genetic changes occur in the Brazilian population. The goal is to improve diagnosis and care for these hereditary diseases.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for ARRHYTHMOGENIC RIGHT VENTRICULAR DYSPLASIA are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

arrhythmogenic right ventricular cardiomyopathy Brugada syndrome catecholaminergic polymorphic ventricular tachycardia Death, Sudden, Cardiac dilated cardiomyopathy Ehlers-Danlos Syndrome, Type IV Ehlers-Danlos syndrome, vascular type familial hypercholesterolemia Hyperlipoproteinemia Type II hypertrophic cardiomyopathy Loeys-Dietz syndrome long QT syndrome Marfan syndrome non-compaction cardiomyopathy Polymorphic Catecholaminergic Ventricular Tachycardia restrictive cardiomyopathy short QT syndrome sudden cardiac arrest

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ARRHYTHMOGENIC RIGHT VENTRICULAR DYSPLASIA BRUGADA SYNDROME CARDIOMYOPATHY RESTRICTIVE CARDIOMYOPATHY, DILATED CARDIOMYOPATHY, HYPERTROPHIC CATECHOLAMINERGIC POLYMORPHIC VENTRICULAR TACHYCARDIA EHLERS-DANLOS SYNDROME, VASCULAR TYPE FAMILIAL HYPERCHOLESTEROLEMIA LOEYS-DIETZ SYNDROME LONG QT SYNDROME MARFAN SYNDROME NON-COMPACTION CARDIOMYOPATHY SHORT QT SYNDROME SUDDEN CARDIAC DEATH

Contacts and locations

Locations

Centro Multidisciplinar de Ensino Especializado e Pesquisa Ltda
RECRUITING

Joinville, Santa Catarina, 89204-250, Brazil
Centro de Pesquisa Silvestre Santé
RECRUITING

Rio Branco, Acre, 69915-030, Brazil
Centro de Pesquisas Clínicas Dr. Marco Mota
RECRUITING

Maceió, Alagoas, 57051-160, Brazil
Health & Care
RECRUITING

Belém, Pará, 66093-055, Brazil
Hospital Ana Nery - HAN/SESAB
RECRUITING

Salvador, Estado de Bahia, 40320-010, Brazil
Hospital Evangélico de Vila Velha
RECRUITING

Vila Velha, Espírito Santo, 29118-060, Brazil
Hospital Felicio Rocho - HFR
RECRUITING

Belo Horizonte, Minas Gerais, 30110-934, Brazil
Hospital Universitário Clementino Fraga Filho - UFRJ
RECRUITING

Rio de Janeiro, Rio de Janeiro, 21941-913, Brazil
Hospital Universitário Onofre Lopes - UFRN
RECRUITING

Natal, Rio Grande do Norte, 59012-300, Brazil
Hospital Universitário Pedro Ernesto - UERJ
RECRUITING

Rio de Janeiro, Rio de Janeiro, 20551-030, Brazil
Hospital Universitário Professor Edgard Santos
RECRUITING

Salvador, Estado de Bahia, 40110-060, Brazil
Hospital Universitário São Francisco na Providência de Deus, USF-SP
RECRUITING

Bragança Paulista, São Paulo, 12916-542, Brazil
Hospital Universitário da Unifap
RECRUITING

Macapá, Amapá, 68903-419, Brazil
Hospital Universitário da Universidade Federal de São Carlos
RECRUITING

São Carlos, São Paulo, 13566-448, Brazil
Hospital das Clínicas da Universidade Federal de Goiás - HC-UFG
RECRUITING

Goiânia, Goiás, 74605-050, Brazil
Hospital das Clínicas de Porto Alegre - UFRGS
RECRUITING

Porto Alegre, Rio Grande do Sul, 90035-903, Brazil
Hospital de Messejana Dr. Carlos Alberto Studart Gomes
RECRUITING

Fortaleza, Ceará, 60840-285, Brazil
Hospital do Coracao
RECRUITING

São Paulo, São Paulo, 04004-030, Brazil
Instituto Nacional de Cardiologia
RECRUITING

Rio de Janeiro, Rio de Janeiro, 22240-006, Brazil
Instituto PENSI
RECRUITING

Consolação, São Paulo, 01228-200, Brazil
Instituto de Cardiologia - Fundação Universitária de Cardiologia de Porto Alegre - IC-FUC
RECRUITING

Porto Alegre, Rio Grande do Sul, 90040-370, Brazil
Instituto de Cardiologia e Transplantes do Distrito Federal
RECRUITING

Brasília, Federal District, 70675-731, Brazil
Instituto de Pesquisa e Ensino em Saúde - IPES
RECRUITING

Porto Velho, Rondônia, 76801-098, Brazil
Instituto de Puericultura e Pediatria Martagão Gesteira
RECRUITING

Rio de Janeiro, Rio de Janeiro, 21941-912, Brazil
Liga Mineira de Ressuscitação Cardiopulmonar
RECRUITING

Belo Horizonte, Minas Gerais, 30130-110, Brazil
Santa Casa de Misericórdia de Montes Claros
RECRUITING

Montes Claros, Minas Gerais, 39401-001, Brazil
Universidade Federal do Tocantins
RECRUITING

Palmas, Tocantins, 77001-090, Brazil

More trials for these conditions

Other studies related to the condition(s) this trial covers.