Hospital Do Coracao

This study tests whether giving vasopressin early, along with norepinephrine, is better than waiting to use it as a rescue treatment for people with septic shock. About 2,800 critically ill adults will be randomly assigned to one of two strategies. The main goal is to see which a…

The EPOCA trial is testing whether a daily 'polypill' (combining blood pressure, cholesterol, and blood-thinning medications) plus the anti-inflammatory drug colchicine can reduce major heart and limb events in people with established heart disease. Over 7,700 participants aged 4…

This study is building a registry of 1,211 people in Brazil who have inherited heart conditions like cardiomyopathy, arrhythmias, and Marfan syndrome. Researchers will collect DNA samples and medical information to discover which genes are most commonly affected and how often the…