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New trial tests best timing for sepsis drug to save lives and kidneys

NCT ID NCT06464510

Recruiting now Disease control Sponsor: Hospital do Coracao Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether giving vasopressin early, along with norepinephrine, is better than waiting to use it as a rescue treatment for people with septic shock. About 2,800 critically ill adults will be randomly assigned to one of two strategies. The main goal is to see which approach reduces the chance of death or the need for kidney dialysis within 28 days.

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Conditions

The condition(s) this trial relates to.

Critical Illness diabetes insipidus toxic shock syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

SEPTIC SHOCK

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • BP-A Beneficiência Portuguesa de São Paulo

    NOT_YET_RECRUITING

    São Paulo, São Paulo, Brazil

    Contact Email: •••••@•••••

  • Hospital Alemão Oswaldo Cruz

    NOT_YET_RECRUITING

    São Paulo, São Paulo, Brazil

    Contact

  • Hospital Geral de Caxias do Sul

    RECRUITING

    Caxias do Sul, Rio Grande do Sul, Brazil

    Contact

  • Hospital Nereu Ramos

    RECRUITING

    Florianópolis, Santa Catarina, Brazil

    Contact Email: •••••@•••••

  • Hospital SEPACO

    NOT_YET_RECRUITING

    São Paulo, S, Brazil

    Contact

  • Hospital São Paulo - UNIFESP

    RECRUITING

    São Paulo, São Paulo, Brazil

    Contact Email: •••••@•••••

  • Hospital de Amor - Unidade Barretos (Fundação PIO XII)

    NOT_YET_RECRUITING

    Barretos, São Paulo, Brazil

    Contact

  • Hospital do Coracao

    RECRUITING

    São Paulo, São Paulo, 05435000, Brazil

    Contact

    Contact

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